JP2020535599A - 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 - Google Patents

同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 Download PDF

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JP2020535599A
JP2020535599A JP2020517087A JP2020517087A JP2020535599A JP 2020535599 A JP2020535599 A JP 2020535599A JP 2020517087 A JP2020517087 A JP 2020517087A JP 2020517087 A JP2020517087 A JP 2020517087A JP 2020535599 A JP2020535599 A JP 2020535599A
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Prior art keywords
ion
intensity
mrm
precursor
mass
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Japanese (ja)
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JP2020535599A5 (enExample
Inventor
ブランク， イブ ル
ブランク， イブ ル
Original Assignee
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド
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Publication of JP2020535599A publication Critical patent/JP2020535599A/ja
Publication of JP2020535599A5 publication Critical patent/JP2020535599A5/ja
Priority to JP2024062123A priority Critical patent/JP2024083502A/ja
Withdrawn legal-status Critical Current

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
    • H01J49/4215—Quadrupole mass filters

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2020517087A 2017-09-29 2018-09-25 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 Withdrawn JP2020535599A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024062123A JP2024083502A (ja) 2017-09-29 2024-04-08 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762565140P 2017-09-29 2017-09-29
US62/565,140 2017-09-29
PCT/IB2018/057395 WO2019064173A1 (en) 2017-09-29 2018-09-25 EVALUATION OF PIC MRM PURITY WITH SELECTIVE MS / MS OF ISOTOPES

Related Child Applications (1)

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JP2024062123A Division JP2024083502A (ja) 2017-09-29 2024-04-08 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定

Publications (2)

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JP2020535599A true JP2020535599A (ja) 2020-12-03
JP2020535599A5 JP2020535599A5 (enExample) 2021-11-11

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JP2020517087A Withdrawn JP2020535599A (ja) 2017-09-29 2018-09-25 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定
JP2024062123A Pending JP2024083502A (ja) 2017-09-29 2024-04-08 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定

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JP2024062123A Pending JP2024083502A (ja) 2017-09-29 2024-04-08 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定

Country Status (5)

Country Link
US (1) US11024494B2 (enExample)
EP (1) EP3688788B1 (enExample)
JP (2) JP2020535599A (enExample)
CN (1) CN111095477B (enExample)
WO (1) WO2019064173A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3916754A1 (en) * 2020-05-28 2021-12-01 Thermo Fisher Scientific (Bremen) GmbH Methods and apparatus for determining interference in ms scan data, filtering ions and performing mass spectrometry analysis on a sample
US20230393107A1 (en) * 2020-10-30 2023-12-07 Dh Technologies Development Pte. Ltd. Compound Identification by Mass Spectrometry
US20240355605A1 (en) * 2021-09-03 2024-10-24 Dh Technologies Development Pte. Ltd. Prediction of precursor charge state in dm-swath analysis
US20240420939A1 (en) * 2021-11-01 2024-12-19 Dh Technologies Development Pte. Ltd. Ultra high throughput screening combined with definitive testing in a single sample preparation step

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006284305A (ja) * 2005-03-31 2006-10-19 Nec Corp 分析方法および分析システム
JP2007263641A (ja) * 2006-03-28 2007-10-11 Shimadzu Corp 構造解析システム
JP2014517477A (ja) * 2011-06-03 2014-07-17 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド Ｓｒｍアッセイにおけるバックグラウンド干渉の決定のためのｔｏｆ−ｍｓｍｓデータの可変ｘｉｃ幅の使用
US20160314951A1 (en) * 2015-04-24 2016-10-27 Thermo Fisher Scientific (Bremen) Gmbh Method of Producing a Mass Spectrum

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US8067728B2 (en) * 2008-02-22 2011-11-29 Dh Technologies Development Pte. Ltd. Method of improving signal-to-noise for quantitation by mass spectrometry
US8335655B2 (en) * 2008-05-30 2012-12-18 Dh Technologies Development Pte. Ltd. Intelligent saturation control for compound specific optimization of MRM
WO2012035412A2 (en) * 2010-09-15 2012-03-22 Dh Technologies Development Pte. Ltd. Data independent acquisition of production spectra and reference spectra library matching
CA2862834C (en) * 2012-01-10 2020-06-16 David B. Krizman Srm/mrm assay for the insulin receptor protein
GB2525709B (en) * 2014-02-04 2018-07-11 Micromass Ltd Optimized multiple reaction monitoring or single ion recording method
WO2015189605A1 (en) 2014-06-11 2015-12-17 Micromass Uk Limited Ion profiling with a scanning quadrupole mass filter
WO2016125059A1 (en) * 2015-02-05 2016-08-11 Dh Technologies Development Pte. Ltd. Interference detection and peak of interest deconvolution

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006284305A (ja) * 2005-03-31 2006-10-19 Nec Corp 分析方法および分析システム
JP2007263641A (ja) * 2006-03-28 2007-10-11 Shimadzu Corp 構造解析システム
JP2014517477A (ja) * 2011-06-03 2014-07-17 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド Ｓｒｍアッセイにおけるバックグラウンド干渉の決定のためのｔｏｆ−ｍｓｍｓデータの可変ｘｉｃ幅の使用
US20160314951A1 (en) * 2015-04-24 2016-10-27 Thermo Fisher Scientific (Bremen) Gmbh Method of Producing a Mass Spectrum

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SUSAN E ABBATIELLO ET AL.: ""Automated Detection of Inaccurate and Imprecise Transitions in Peptide Quantification by Multiple", CLINICAL CHEMISTRY, vol. 56, no. 2, JPN7023001510, 2010, pages 291 - 305, XP055389557, ISSN: 0005040795, DOI: 10.1373/clinchem.2009.138420 *
Y． BAO ET AL.: ""Detection and correction of interference in SRM analysis"", METHODS, vol. 61, no. 3, JPN6023015621, 2013, pages 299 - 303, ISSN: 0005040796 *

Also Published As

Publication number Publication date
EP3688788B1 (en) 2024-02-21
US20200279725A1 (en) 2020-09-03
US11024494B2 (en) 2021-06-01
JP2024083502A (ja) 2024-06-21
EP3688788A1 (en) 2020-08-05
WO2019064173A1 (en) 2019-04-04
CN111095477B (zh) 2023-12-22
EP3688788A4 (en) 2021-08-18
CN111095477A (zh) 2020-05-01

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