JP2020535203A5 - - Google Patents
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- Publication number
- JP2020535203A5 JP2020535203A5 JP2020518033A JP2020518033A JP2020535203A5 JP 2020535203 A5 JP2020535203 A5 JP 2020535203A5 JP 2020518033 A JP2020518033 A JP 2020518033A JP 2020518033 A JP2020518033 A JP 2020518033A JP 2020535203 A5 JP2020535203 A5 JP 2020535203A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- nucleotide sequence
- sequence encoding
- fragment
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000002773 nucleotide Substances 0.000 claims 23
- 125000003729 nucleotide group Chemical group 0.000 claims 23
- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 239000012634 fragment Substances 0.000 claims 19
- 108090000623 proteins and genes Proteins 0.000 claims 19
- 102100025215 CCN family member 5 Human genes 0.000 claims 13
- 101000934220 Homo sapiens CCN family member 5 Proteins 0.000 claims 13
- 102000004169 proteins and genes Human genes 0.000 claims 12
- 206010003119 arrhythmia Diseases 0.000 claims 6
- 230000006793 arrhythmia Effects 0.000 claims 6
- 239000013604 expression vector Substances 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 5
- 239000004480 active ingredient Substances 0.000 claims 3
- 241001672814 Porcine teschovirus 1 Species 0.000 claims 2
- 241000700618 Vaccinia virus Species 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 241000701161 unidentified adenovirus Species 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000007469 Actins Human genes 0.000 claims 1
- 108010085238 Actins Proteins 0.000 claims 1
- 206010003130 Arrhythmia supraventricular Diseases 0.000 claims 1
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 1
- 101000746373 Homo sapiens Granulocyte-macrophage colony-stimulating factor Proteins 0.000 claims 1
- 101100232904 Homo sapiens IL2 gene Proteins 0.000 claims 1
- 101100232919 Homo sapiens IL4 gene Proteins 0.000 claims 1
- 101100321817 Human parvovirus B19 (strain HV) 7.5K gene Proteins 0.000 claims 1
- 101150103227 IFN gene Proteins 0.000 claims 1
- 241000713666 Lentivirus Species 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 206010047281 Ventricular arrhythmia Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000013601 cosmid vector Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 206010039083 rhinitis Diseases 0.000 claims 1
- 241001529453 unidentified herpesvirus Species 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170127550 | 2017-09-29 | ||
| KR10-2017-0127550 | 2017-09-29 | ||
| PCT/KR2018/011529 WO2019066556A1 (ko) | 2017-09-29 | 2018-09-28 | 심장 부정맥의 예방 또는 치료용 약학적 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020535203A JP2020535203A (ja) | 2020-12-03 |
| JP2020535203A5 true JP2020535203A5 (enExample) | 2021-11-04 |
| JP7178118B2 JP7178118B2 (ja) | 2022-11-25 |
Family
ID=65902177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020518033A Active JP7178118B2 (ja) | 2017-09-29 | 2018-09-28 | 不整脈を予防または治療するための医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11761019B2 (enExample) |
| EP (1) | EP3689363A4 (enExample) |
| JP (1) | JP7178118B2 (enExample) |
| KR (2) | KR20190038425A (enExample) |
| CN (1) | CN111542334B (enExample) |
| WO (1) | WO2019066556A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7240749B2 (ja) * | 2017-09-29 | 2023-03-16 | ベスファジェン・インコーポレイテッド | 心不全の予防または治療のための医薬組成物 |
| KR20240173703A (ko) * | 2023-06-05 | 2024-12-13 | (주)벳바젠 | 포스포람반의 단백질 포스파타아제 1-매개 탈인산화 억제용 데코이 펩타이드를 암호화하는 뉴클레오타이드 및 ccn5 단백질 또는 이의 단편을 암호화하는 뉴클레오타이드를 포함하는 유전자 컨스트럭트 및 이의 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US20090239940A1 (en) | 1997-07-22 | 2009-09-24 | Del Monte Federica | Treating heart failure and ventricular arrhythmias |
| EP1382347A1 (en) * | 2002-07-17 | 2004-01-21 | UNIVERSITE PARIS 7 - Denis DIDEROT | Use of CCN protein family members for the treatment of disorder associated to an altered calcium and/or sodium flux |
| US20040106954A1 (en) * | 2002-11-15 | 2004-06-03 | Whitehurst Todd K. | Treatment of congestive heart failure |
| WO2006007444A2 (en) | 2004-06-16 | 2006-01-19 | The Trustees Of Columbia University In The City Of New York | CaMKII/CALCIUM CHANNEL BINDING-RELATED COMPOSITIONS AND METHODS |
| KR101187814B1 (ko) * | 2010-03-22 | 2012-10-08 | 광주과학기술원 | 심부전 예방 또는 치료용 약제학적 조성물 및 심부전 예방 또는 치료제의 스크리닝 방법 |
| EP3004343B1 (en) * | 2013-06-07 | 2018-10-10 | The Regents of The University of California | Cycle adenosine monophosphate-incompetent adenylyl cyclase and compositions and methods for treating heart failure and increasing cardiac function |
| CN108778311A (zh) * | 2015-11-13 | 2018-11-09 | 贝特基因 | 用于治疗心脏纤维化的药物组合物 |
-
2018
- 2018-09-28 WO PCT/KR2018/011529 patent/WO2019066556A1/ko not_active Ceased
- 2018-09-28 KR KR1020180115954A patent/KR20190038425A/ko not_active Ceased
- 2018-09-28 EP EP18861445.7A patent/EP3689363A4/en active Pending
- 2018-09-28 US US16/651,889 patent/US11761019B2/en active Active
- 2018-09-28 CN CN201880077650.2A patent/CN111542334B/zh active Active
- 2018-09-28 JP JP2020518033A patent/JP7178118B2/ja active Active
-
2019
- 2019-07-16 KR KR1020190085741A patent/KR20190087376A/ko not_active Ceased
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