JP2020534313A5 - - Google Patents

Download PDF

Info

Publication number
JP2020534313A5
JP2020534313A5 JP2020516552A JP2020516552A JP2020534313A5 JP 2020534313 A5 JP2020534313 A5 JP 2020534313A5 JP 2020516552 A JP2020516552 A JP 2020516552A JP 2020516552 A JP2020516552 A JP 2020516552A JP 2020534313 A5 JP2020534313 A5 JP 2020534313A5
Authority
JP
Japan
Prior art keywords
cells
cell composition
composition according
isolated cell
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020516552A
Other languages
English (en)
Japanese (ja)
Other versions
JP7475684B2 (ja
JP2020534313A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/051971 external-priority patent/WO2019060558A1/en
Publication of JP2020534313A publication Critical patent/JP2020534313A/ja
Publication of JP2020534313A5 publication Critical patent/JP2020534313A5/ja
Application granted granted Critical
Publication of JP7475684B2 publication Critical patent/JP7475684B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020516552A 2017-09-20 2018-09-20 養子療法のための抗原特異的t細胞を含む細胞組成物 Active JP7475684B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762561044P 2017-09-20 2017-09-20
US62/561,044 2017-09-20
US201862656679P 2018-04-12 2018-04-12
US62/656,679 2018-04-12
PCT/US2018/051971 WO2019060558A1 (en) 2017-09-20 2018-09-20 CELLULAR COMPOSITIONS COMPRISING ANTIGEN-SPECIFIC T CELLS FOR ADOPTIVE THERAPY

Publications (3)

Publication Number Publication Date
JP2020534313A JP2020534313A (ja) 2020-11-26
JP2020534313A5 true JP2020534313A5 (https=) 2021-10-14
JP7475684B2 JP7475684B2 (ja) 2024-04-30

Family

ID=65810886

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020516552A Active JP7475684B2 (ja) 2017-09-20 2018-09-20 養子療法のための抗原特異的t細胞を含む細胞組成物

Country Status (13)

Country Link
US (2) US20190119639A1 (https=)
EP (1) EP3684402A4 (https=)
JP (1) JP7475684B2 (https=)
KR (1) KR102850471B1 (https=)
CN (1) CN111629748A (https=)
AU (1) AU2018337960B2 (https=)
BR (1) BR112020005552A2 (https=)
CA (1) CA3076490A1 (https=)
IL (1) IL273452B2 (https=)
MX (1) MX2020003129A (https=)
RU (1) RU2020113627A (https=)
SG (1) SG11202002523YA (https=)
WO (1) WO2019060558A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006065495A2 (en) 2004-11-24 2006-06-22 Fred Hutchinson Cancer Research Center Methods of using il-21 for adoptive immunotherapy and identification of tumor antigens
CA3081840A1 (en) 2017-11-08 2019-05-16 Neon Therapeutics, Inc. T cell manufacturing compositions and methods
CA3122131A1 (en) * 2018-09-21 2020-03-26 Zonghai Li Method for gene editing of cell on the basis of crispr/cas system
AU2019375997A1 (en) * 2018-11-08 2021-06-03 Neximmune, Inc. T cell compositions with improved phenotypic properties
TWI777160B (zh) * 2019-05-08 2022-09-11 美商百歐恩泰美國公司 T細胞製備組合物及方法
US12365871B2 (en) 2020-04-28 2025-07-22 Lyell Immunopharma, Inc. Methods for culturing cells
EP4334361A1 (en) 2021-05-05 2024-03-13 Immatics Biotechnologies GmbH Antigen binding proteins specifically binding prame
US20240368545A1 (en) * 2021-05-07 2024-11-07 Yasuhito TOKUMOTO Manufacturing method of memory t cells
CN113945715B (zh) * 2021-08-30 2023-04-21 四川大学华西医院 供者特异性IL-21和IFN-γ的检测方法及应用
WO2023159088A1 (en) * 2022-02-15 2023-08-24 Marker Therapeutics, Inc. Compositions and methods for antigen-specific t cell expansion

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268411B1 (en) 1997-09-11 2001-07-31 The Johns Hopkins University Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
US20050169898A1 (en) * 1997-04-15 2005-08-04 Jianlin Gong Cell fusions and methods of making and using the same
US8748405B2 (en) * 2007-01-26 2014-06-10 City Of Hope Methods and compositions for the treatment of cancer or other diseases
AU2012305931B2 (en) 2011-09-08 2017-09-07 Yeda Research And Development Co. Ltd Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment
US10316289B2 (en) 2012-09-06 2019-06-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of producing T memory stem cell populations
KR102453188B1 (ko) 2013-06-24 2022-10-07 넥스이뮨, 인크. 면역요법을 위한 조성물 및 방법
CN107002038B (zh) * 2014-09-17 2021-10-15 约翰·霍普金斯大学 用于识别、富集和/或扩增抗原特异性t细胞的试剂和方法
EP3034092A1 (en) 2014-12-17 2016-06-22 Université de Lausanne Adoptive immunotherapy for treating cancer
SG11201705064XA (en) 2014-12-24 2017-07-28 Neximmune Inc Nanoparticle compositions and methods for immunotherapy
CN106714836A (zh) * 2015-06-05 2017-05-24 H·李·莫菲特癌症中心研究有限公司 Gm‑csf/cd40l疫苗和检查点抑制剂联合治疗
US9790467B2 (en) * 2015-09-22 2017-10-17 Qt Holdings Corp Methods and compositions for activation or expansion of T lymphocytes
MX2018005618A (es) * 2015-11-05 2018-08-01 Juno Therapeutics Inc Receptores quimericos que contienen dominios inductores de traf y composiciones y metodos relacionados.
SG11201804648RA (en) * 2015-12-04 2018-06-28 Univ Texas Slc45a2 peptides for immunotherapy
TW201621210A (zh) * 2016-02-26 2016-06-16 液光固態照明股份有限公司 發光二極體光源及燈具
RU2021107053A (ru) * 2016-03-16 2021-08-24 Нексиммьюн, Инк. Получение антигенспецифических t-клеток

Similar Documents

Publication Publication Date Title
JP2020534313A5 (https=)
Butler et al. Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell
RU2020113627A (ru) Композиции клеток, содержащие антигенспецифические т-клетки, для адоптивной терапии
Hwang et al. Cognate memory CD4+ T cells generated with dendritic cell priming influence the expansion, trafficking, and differentiation of secondary CD8+ T cells and enhance tumor control
Baxevanis et al. Tumor-specific CD4+ T lymphocytes from cancer patients are required for optimal induction of cytotoxic T cells against the autologous tumor
AU2015311761B2 (en) Activation of marrow infiltrating lymphocytes in hypoxic alternating with normoxic conditions
Kalinski et al. Dendritic cell-based therapeutic cancer vaccines: what we have and what we need
US11027001B2 (en) Therapeutic cancer vaccines derived from a novel dendritic cell line
JP6522671B2 (ja) 自己癌抗原特異的cd8+t細胞の分離及び増殖方法
Ye et al. Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes
Lee et al. Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia
Ferlazzo et al. Dendritic cells generated from CD34+ progenitor cells with flt3 ligand, c-kit ligand, GM-CSF, IL-4, and TNF-α are functional antigen-presenting cells resembling mature monocyte-derived dendritic cells
US20160208216A1 (en) Methods of cell culture for adoptive cell therapy
Khan et al. Expanded human blood-derived γδT cells display potent antigen-presentation functions
CN120536375A (zh) 用于治疗b细胞恶性肿瘤和其它癌症的自体t细胞的生产方法及其组合物
Willemen et al. Engineering monocyte-derived dendritic cells to secrete interferon-α enhances their ability to promote adaptive and innate anti-tumor immune effector functions
CN102618498A (zh) Hla-a0201限制性抗原特异性ctl制备方法
Salgaller et al. Generation of specific anti-melanoma reactivity by stimulation of human tumor-infiltrating lymphocytes with MAGE-1 synthetic peptide
KR20210095157A (ko) 개선된 표현형 속성을 갖는 t 세포 조성물
Wu et al. CD19 chimeric antigen receptor–redirected T cells combined with epidermal growth factor receptor pathway substrate 8 peptide–derived dendritic cell vaccine in leukemia
Kayser et al. Rapid generation of NY-ESO-1-specific CD4+ THELPER1 cells for adoptive T-cell therapy
Zhang et al. Generation of mouse pluripotent stem cell–derived proliferating myeloid cells as an unlimited source of functional antigen-presenting cells
CN117580946A (zh) 用于产生抗原特异性t细胞的方法
Chevaleyre et al. The tumor antigen cyclin B1 hosts multiple CD4 T cell epitopes differently recognized by pre-existing naive and memory cells in both healthy and cancer donors
WO2019217512A1 (en) Compositions and methods for culturing and expanding cells