JP2020533968A5 - - Google Patents
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- Publication number
- JP2020533968A5 JP2020533968A5 JP2020511199A JP2020511199A JP2020533968A5 JP 2020533968 A5 JP2020533968 A5 JP 2020533968A5 JP 2020511199 A JP2020511199 A JP 2020511199A JP 2020511199 A JP2020511199 A JP 2020511199A JP 2020533968 A5 JP2020533968 A5 JP 2020533968A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acids
- sequence
- sequences
- seq
- raavrec2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762550458P | 2017-08-25 | 2017-08-25 | |
| US62/550,458 | 2017-08-25 | ||
| PCT/US2018/047466 WO2019040586A1 (en) | 2017-08-25 | 2018-08-22 | RECOMBINANT ADENO-ASSOCIATE VECTORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020533968A JP2020533968A (ja) | 2020-11-26 |
| JP2020533968A5 true JP2020533968A5 (enExample) | 2021-09-30 |
Family
ID=65439655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511199A Pending JP2020533968A (ja) | 2017-08-25 | 2018-08-22 | 組換えアデノ随伴ベクター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190085358A1 (enExample) |
| EP (1) | EP3655041A4 (enExample) |
| JP (1) | JP2020533968A (enExample) |
| KR (1) | KR20200042935A (enExample) |
| CN (1) | CN111163811A (enExample) |
| AU (1) | AU2018320849A1 (enExample) |
| CA (1) | CA3073937A1 (enExample) |
| IL (1) | IL272655A (enExample) |
| MX (1) | MX2020002148A (enExample) |
| WO (1) | WO2019040586A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2594616A (en) | 2018-11-21 | 2021-11-03 | Certego Therapeutics Inc | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| US20230118087A1 (en) * | 2019-09-03 | 2023-04-20 | Krystal Biotech, Inc. | Compositions and methods for the treatment of congenital ichthyoses |
| IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
| JP2023540756A (ja) * | 2020-09-04 | 2023-09-26 | オハイオ・ステイト・イノベーション・ファウンデーション | 向上した形質導入効率及び脳内における広範な分布を有する組換えアデノ随伴ウイルスベクターの新規の操作されたキャプシド血清型 |
| WO2023044306A1 (en) * | 2021-09-14 | 2023-03-23 | California Institute Of Technology | Aav capsid variants |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69939169D1 (de) * | 1998-05-28 | 2008-09-04 | Us Gov Health & Human Serv | Aav5 vektoren und deren verwendung |
| CA2376400A1 (en) * | 1999-06-08 | 2000-12-14 | University Of Iowa Research Foundation | Compounds and methods to enhance raav transduction |
| US7169594B2 (en) * | 2002-08-12 | 2007-01-30 | Regents Of The University Of Michigan | Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway |
| US7427396B2 (en) * | 2004-06-03 | 2008-09-23 | Genzyme Corporation | AAV vectors for gene delivery to the lung |
| US7838657B2 (en) * | 2004-12-03 | 2010-11-23 | University Of Massachusetts | Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences |
| US8999678B2 (en) * | 2005-04-07 | 2015-04-07 | The Trustees Of The University Of Pennsylvania | Method of increasing the function of an AAV vector |
| US9415121B2 (en) * | 2008-12-19 | 2016-08-16 | Nationwide Children's Hospital | Delivery of MECP2 polynucleotide using recombinant AAV9 |
| EP2692868A1 (en) * | 2012-08-02 | 2014-02-05 | Universitat Autònoma De Barcelona | Adeno-associated viral (AAV) vectors useful for transducing adipose tissue |
| US10821154B2 (en) * | 2013-05-01 | 2020-11-03 | Genzyme Corporation | Compositions and methods for treating spinal muscular atrophy |
| CA3209883A1 (en) * | 2013-07-22 | 2015-01-29 | The Children's Hospital Of Philadelphia | Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| US20150313903A1 (en) * | 2014-05-05 | 2015-11-05 | Ovid Therapeutics Inc. | Methods of treating cognitive impairment associated with neurodegenerative disorders |
| BR112016028023A2 (pt) * | 2014-05-30 | 2017-08-22 | Univ Leland Stanford Junior | Composições e métodos de administração de tratamentos para infecções virais latentes |
| WO2015191508A1 (en) * | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| EP3795580A1 (en) * | 2014-10-03 | 2021-03-24 | University of Massachusetts | High efficiency library-identified aav vectors |
| DK3387137T3 (da) * | 2015-12-11 | 2021-05-03 | California Inst Of Techn | Målretningspeptider til styring af adeno-associerede virusser (aav`er) |
| WO2017106354A1 (en) * | 2015-12-14 | 2017-06-22 | The Trustees Of The University Of Pennsylvania | Adeno-associated viral vectors useful in treatment of spinal muscular atropy |
| CN116333057A (zh) * | 2016-05-13 | 2023-06-27 | 4D分子治疗有限公司 | 腺相关病毒变体衣壳和其使用方法 |
| AU2018221738B2 (en) * | 2017-02-15 | 2024-06-27 | The University Of North Carolina At Chapel Hill | Methods and compositions for gene transfer across the vasculature |
| CN110621318A (zh) * | 2017-03-15 | 2019-12-27 | 奥维德医疗公司 | 排他地由设计者药物激活的设计者受体在治疗癫痫发作紊乱中的用途 |
| EP3710010A4 (en) * | 2017-12-20 | 2021-09-22 | Ovid Therapeutics Inc. | USE OF HM4DI IN TREATMENT OF SEQUENCE DISEASES |
| WO2019241624A1 (en) * | 2018-06-14 | 2019-12-19 | Ovid Therapeutics Inc. | Use of mir-92a or mir-145 in the treatment of angelman syndrome |
| CN113966399A (zh) * | 2018-09-26 | 2022-01-21 | 加州理工学院 | 用于靶向基因疗法的腺相关病毒组合物 |
| US10557149B1 (en) * | 2019-07-15 | 2020-02-11 | Vigene Biosciences, Inc. | Recombinantly-modified adeno-associated virus helper vectors and their use to improve the packaging efficiency of recombinantly-modified adeno-associated virus |
| KR20220098384A (ko) * | 2019-11-19 | 2022-07-12 | 아스클레피오스 바이오파마슈티컬, 인크. | 폼페병 및 리소좀 장애를 치료하기 위한 간-특이적 프로모터를 포함하는 치료적 아데노-관련 바이러스 |
| IL293431A (en) * | 2019-12-05 | 2022-07-01 | Univ Texas | Transgene cassettes designed to express human mecp2 gene |
| CA3116391A1 (en) * | 2020-09-14 | 2022-03-14 | President And Fellows Of Harvard College | Recombinant adeno associated virus encoding clarin-1 and uses thereof |
| US20240309055A1 (en) * | 2021-02-03 | 2024-09-19 | The University Of North Carolina At Chapel Hill | Protein m analogs and fusion proteins and their use for inhibiting antibody function |
| WO2022235702A1 (en) * | 2021-05-04 | 2022-11-10 | California Institute Of Technology | Recombinant aavs for delivery to central nervous system and brain vasculature |
| CN114259502A (zh) * | 2021-12-24 | 2022-04-01 | 南京鼓楼医院 | 一种基于脂肪组织的中枢靶向递送siRNA的方法及应用 |
| CN116350801A (zh) * | 2022-11-22 | 2023-06-30 | 四川至善唯新生物科技有限公司 | 一种重组腺相关病毒载体的药物组合物及其用途 |
-
2018
- 2018-08-22 WO PCT/US2018/047466 patent/WO2019040586A1/en not_active Ceased
- 2018-08-22 US US16/108,393 patent/US20190085358A1/en not_active Abandoned
- 2018-08-22 JP JP2020511199A patent/JP2020533968A/ja active Pending
- 2018-08-22 CN CN201880064381.6A patent/CN111163811A/zh active Pending
- 2018-08-22 AU AU2018320849A patent/AU2018320849A1/en not_active Abandoned
- 2018-08-22 KR KR1020207008689A patent/KR20200042935A/ko not_active Withdrawn
- 2018-08-22 EP EP18849356.3A patent/EP3655041A4/en not_active Withdrawn
- 2018-08-22 CA CA3073937A patent/CA3073937A1/en active Pending
- 2018-08-22 MX MX2020002148A patent/MX2020002148A/es unknown
-
2020
- 2020-02-13 IL IL272655A patent/IL272655A/en unknown
-
2021
- 2021-08-12 US US17/400,768 patent/US20210371880A1/en not_active Abandoned
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