JP2020533604A5 - - Google Patents
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- JP2020533604A5 JP2020533604A5 JP2020515677A JP2020515677A JP2020533604A5 JP 2020533604 A5 JP2020533604 A5 JP 2020533604A5 JP 2020515677 A JP2020515677 A JP 2020515677A JP 2020515677 A JP2020515677 A JP 2020515677A JP 2020533604 A5 JP2020533604 A5 JP 2020533604A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- fragments
- level
- proadm
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023006500A JP7544879B2 (ja) | 2017-09-13 | 2023-01-19 | 重篤患者用の療法モニタリングマーカーとしてのｐｒｏ－ａｄｍ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17190912.0 | 2017-09-13 | ||
| EP17190912 | 2017-09-13 | ||
| PCT/EP2018/074722 WO2019053115A1 (en) | 2017-09-13 | 2018-09-13 | USE OF PROADM AS A THERAPEUTIC SURVEILLANCE MARKER FOR CRITICALLY PHASE PATIENTS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023006500A Division JP7544879B2 (ja) | 2017-09-13 | 2023-01-19 | 重篤患者用の療法モニタリングマーカーとしてのｐｒｏ－ａｄｍ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020533604A JP2020533604A (ja) | 2020-11-19 |
| JP2020533604A5 true JP2020533604A5 (https=) | 2021-03-25 |
| JP7329503B2 JP7329503B2 (ja) | 2023-08-18 |
Family
ID=59887050
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515677A Active JP7329503B2 (ja) | 2017-09-13 | 2018-09-13 | 重篤患者用の療法モニタリングマーカーとしてのｐｒｏ－ａｄｍ |
| JP2020515760A Active JP7366007B2 (ja) | 2017-09-13 | 2018-09-13 | プロアドレノメジュリンに基づく輸液療法のガイダンスのための方法 |
| JP2023006500A Active JP7544879B2 (ja) | 2017-09-13 | 2023-01-19 | 重篤患者用の療法モニタリングマーカーとしてのｐｒｏ－ａｄｍ |
| JP2023175415A Abandoned JP2023181226A (ja) | 2017-09-13 | 2023-10-10 | プロアドレノメジュリンに基づく輸液療法のガイダンスのための方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515760A Active JP7366007B2 (ja) | 2017-09-13 | 2018-09-13 | プロアドレノメジュリンに基づく輸液療法のガイダンスのための方法 |
| JP2023006500A Active JP7544879B2 (ja) | 2017-09-13 | 2023-01-19 | 重篤患者用の療法モニタリングマーカーとしてのｐｒｏ－ａｄｍ |
| JP2023175415A Abandoned JP2023181226A (ja) | 2017-09-13 | 2023-10-10 | プロアドレノメジュリンに基づく輸液療法のガイダンスのための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20200300864A1 (https=) |
| EP (2) | EP3682245A1 (https=) |
| JP (4) | JP7329503B2 (https=) |
| CN (2) | CN111065927B (https=) |
| BR (1) | BR112020004138A2 (https=) |
| CA (1) | CA3075440A1 (https=) |
| WO (2) | WO2019053116A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026013199A1 (en) | 2024-07-12 | 2026-01-15 | Cezanne S.A.S. | Clinical immunoassay with early signal measurement |
| CN118976116B (zh) * | 2024-10-22 | 2025-01-24 | 四川大学华西医院 | 琥珀酰明胶在制备腹膜透析液中的用途以及一种含琥珀酰明胶、枸橼酸钠的腹膜透析液 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2570703B1 (fr) | 1984-09-26 | 1988-07-08 | Commissariat Energie Atomique | Complexes macropolycycliques de terres rares et application a titre de marqueurs fluorescents |
| US4882733A (en) | 1987-03-13 | 1989-11-21 | Ford Aerospace Corporation | Method and apparatus for combining encoding and modulation |
| FR2664699B1 (fr) | 1990-07-13 | 1995-08-18 | Cis Bio Int | Procede d'amplification du signal d'emission d'un compose luminescent. |
| DE69602756T2 (de) | 1995-08-18 | 2000-02-10 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville | Funktionelle rolle von adrenomedullin(am) und dem gen-verwandten produkt(pamp) in der menschlichen pathologie und physiologie |
| KR100425525B1 (ko) | 2000-11-21 | 2004-03-30 | 재단법인서울대학교산학협력재단 | 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트 |
| US6864237B2 (en) * | 2002-05-17 | 2005-03-08 | Ping Wang | Treatment of shock using adrenomedullin and adrenomedullin binding protein-1 |
| DE10316583A1 (de) | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| CN101208602A (zh) * | 2005-04-15 | 2008-06-25 | 贝克顿迪金森公司 | 脓毒症的诊断 |
| DE102006034142A1 (de) * | 2006-07-24 | 2008-01-31 | B.R.A.H.M.S. Aktiengesellschaft | Verfahren zur Steuerung der Therapie von Patienten mit Herzinsuffizienz anhand der vitro Bestimmung von Schwellenwerten von vasoaktiven Peptiden |
| US9012151B2 (en) * | 2006-11-09 | 2015-04-21 | B.R.A.H.M.S. Gmbh | Methods of diagnosis and risk stratification of adverse events in post myocardial infarction patients using pro-adrenomedullin |
| DE102006060112A1 (de) | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| US8298774B2 (en) | 2007-03-12 | 2012-10-30 | Biomedica Medizinprodukte Gmbh & Co Kg | Diagnosis of septic complications |
| PL2185937T5 (pl) | 2007-09-07 | 2014-12-31 | Univ Zuerich | Sposób wykrywania posocznicy u ludzi |
| ES2486268T3 (es) | 2007-11-16 | 2014-08-18 | Biocartis Nv | Biomarcadores y procedimientos de diagnóstico, predicción y/o pronóstico de septicemia y usos de los mismos |
| JP5989965B2 (ja) * | 2008-01-08 | 2016-09-07 | メルク シャープ エンド ドーム リミテッド | ２−｛４−［（３ｓ）−ピペリジン−３−イル］フェニル｝−２ｈ−インダゾール−７−カルボキサミドの薬学的に許容される塩 |
| EP2131200A1 (en) * | 2008-06-04 | 2009-12-09 | BRAHMS Aktiengesellschaft | A marker for graft failure and mortality |
| US9229013B2 (en) | 2009-05-05 | 2016-01-05 | B.R.A.H.M.S Gmbh | Vasoactive hormone-based stratification of patients suffering from diseases related to endothelial function/dysfunction |
| JP5702371B2 (ja) * | 2009-05-27 | 2015-04-15 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｍｕｃ１のアンタゴニストを使用した、炎症の阻害 |
| EP2438447B1 (en) | 2009-06-05 | 2015-02-18 | B.R.A.H.M.S GmbH | Detection of bacterial infections in subjects suffering from dyspnea. |
| US8383332B2 (en) | 2009-10-13 | 2013-02-26 | B.R.A.H.M.S. Gmbh | Procalcitonin for the diagnosis of bacterial infections and guidance of antibiotic treatment in patients with acute stroke or transient ischemic attack |
| EP2545379B1 (en) | 2010-03-08 | 2015-09-30 | B.R.A.H.M.S GmbH | Procalcitonin for the diagnosis of bacterial infections and guidance of antibiotic treatment in patients with non-specific complaints |
| WO2012059477A1 (en) | 2010-11-01 | 2012-05-10 | B.R.A.H.M.S Gmbh | Prognosis and risk assessment of patients with non-specific complaints |
| SG11201402362VA (en) * | 2011-11-16 | 2014-06-27 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for reducing the risk of mortality in a patient having a chronic or acute disease or acute condition |
| CA2856150A1 (en) * | 2011-11-16 | 2013-05-23 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for regulating the fluid balance in a patient having a chronic or acute disease |
| US11067586B2 (en) * | 2011-11-16 | 2021-07-20 | Sphingotec Gmbh | Adrenomedullin assays and methods for determining mature adrenomedullin |
| DK2780717T3 (en) * | 2011-11-16 | 2017-02-13 | Sphingotec Gmbh | ADRENOMEDULLINASSAYS AND METHODS FOR DETERMINING MODERN ADRENOMEDULLIN |
| US10935548B2 (en) | 2011-12-08 | 2021-03-02 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and renal failure using insulin-like growth factor-binding protein 7 and metalloproteinase inhibitor 2 |
| EP2637023A1 (en) * | 2012-03-08 | 2013-09-11 | B.R.A.H.M.S GmbH | Prediction of outcome in patients with chronic obstructive pulmonary disease |
| EP2976646B1 (en) * | 2013-03-20 | 2020-08-19 | sphingotec GmbH | Adrenomedullin to guide therapy of blood pressure decline |
| US9597730B2 (en) * | 2013-04-19 | 2017-03-21 | United Technologies Corporation | Build plate and apparatus for additive manufacturing |
| US20180348235A1 (en) | 2015-11-27 | 2018-12-06 | B.R.A.H.M.S Gmbh | MR-proADM as marker for the extracellular volume status of a subject |
| EP4231018A3 (en) | 2016-07-08 | 2023-11-15 | SphingoTec GmbH | Adrenomedullin for assessing congestion in a subject with acute heart failure |
| CA3033094A1 (en) | 2016-08-09 | 2018-02-15 | B.R.A.H.M.S Gmbh | Histones and/or proadm as markers indicating an adverse event |
-
2018
- 2018-09-13 WO PCT/EP2018/074723 patent/WO2019053116A1/en not_active Ceased
- 2018-09-13 BR BR112020004138-6A patent/BR112020004138A2/pt unknown
- 2018-09-13 WO PCT/EP2018/074722 patent/WO2019053115A1/en not_active Ceased
- 2018-09-13 JP JP2020515677A patent/JP7329503B2/ja active Active
- 2018-09-13 JP JP2020515760A patent/JP7366007B2/ja active Active
- 2018-09-13 EP EP18765656.6A patent/EP3682245A1/en active Pending
- 2018-09-13 US US16/646,637 patent/US20200300864A1/en active Pending
- 2018-09-13 CN CN201880059136.6A patent/CN111065927B/zh active Active
- 2018-09-13 US US16/646,639 patent/US12517138B2/en active Active
- 2018-09-13 EP EP18765657.4A patent/EP3682246A1/en active Pending
- 2018-09-13 CA CA3075440A patent/CA3075440A1/en active Pending
- 2018-09-13 CN CN201880059366.2A patent/CN111094986B/zh active Active
-
2023
- 2023-01-19 JP JP2023006500A patent/JP7544879B2/ja active Active
- 2023-10-10 JP JP2023175415A patent/JP2023181226A/ja not_active Abandoned
-
2025
- 2025-01-17 US US19/027,967 patent/US20250189539A1/en active Pending
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