JP2020533301A5 - - Google Patents
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- Publication number
- JP2020533301A5 JP2020533301A5 JP2020513648A JP2020513648A JP2020533301A5 JP 2020533301 A5 JP2020533301 A5 JP 2020533301A5 JP 2020513648 A JP2020513648 A JP 2020513648A JP 2020513648 A JP2020513648 A JP 2020513648A JP 2020533301 A5 JP2020533301 A5 JP 2020533301A5
- Authority
- JP
- Japan
- Prior art keywords
- variant polypeptide
- composition
- mutated
- composition according
- agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023133442A JP2023157959A (ja) | 2017-09-06 | 2023-08-18 | インターロイキン－１８バリアントとその利用法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762554605P | 2017-09-06 | 2017-09-06 | |
| US62/554,605 | 2017-09-06 | ||
| US201862652279P | 2018-04-03 | 2018-04-03 | |
| US62/652,279 | 2018-04-03 | ||
| PCT/US2018/049648 WO2019051015A1 (en) | 2017-09-06 | 2018-09-06 | VARIANTS OF INTERLEUKIN-18 AND METHODS OF USE |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023133442A Division JP2023157959A (ja) | 2017-09-06 | 2023-08-18 | インターロイキン－１８バリアントとその利用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020533301A JP2020533301A (ja) | 2020-11-19 |
| JP2020533301A5 true JP2020533301A5 (enExample) | 2021-10-14 |
Family
ID=65517760
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513648A Pending JP2020533301A (ja) | 2017-09-06 | 2018-09-06 | インターロイキン−１８バリアントとその利用法 |
| JP2023133442A Pending JP2023157959A (ja) | 2017-09-06 | 2023-08-18 | インターロイキン－１８バリアントとその利用法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023133442A Pending JP2023157959A (ja) | 2017-09-06 | 2023-08-18 | インターロイキン－１８バリアントとその利用法 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US20190070262A1 (enExample) |
| EP (1) | EP3678681A4 (enExample) |
| JP (2) | JP2020533301A (enExample) |
| KR (1) | KR20200066623A (enExample) |
| CN (1) | CN111315395A (enExample) |
| AU (2) | AU2018330444B2 (enExample) |
| BR (1) | BR112020004389A2 (enExample) |
| CA (1) | CA3080492A1 (enExample) |
| IL (2) | IL272635B2 (enExample) |
| MX (1) | MX2020002542A (enExample) |
| SG (1) | SG11202001384TA (enExample) |
| WO (1) | WO2019051015A1 (enExample) |
| ZA (1) | ZA202307212B (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| EP4293039A4 (en) * | 2021-02-10 | 2025-07-16 | Univ Nagasaki | NEW VARIANT OF HUMAN INTERLEUKIN-18 AND ITS USE |
| US20230146665A1 (en) | 2021-07-27 | 2023-05-11 | Xencor, Inc. | Il-18-fc fusion proteins |
| JP2023024168A (ja) | 2021-08-06 | 2023-02-16 | 国立大学法人 長崎大学 | がんの治療剤 |
| AU2022414067A1 (en) | 2021-12-15 | 2024-05-23 | Genentech, Inc. | Stabilized il-18 polypeptides and uses thereof |
| WO2023118497A1 (en) * | 2021-12-22 | 2023-06-29 | Pieris Pharmaceuticals Gmbh | Novel il-18 variants |
| CN119053347A (zh) | 2022-02-23 | 2024-11-29 | 明峰治疗股份公司 | 免疫抗原特异性il-18免疫细胞因子及其用途 |
| CA3244052A1 (en) * | 2022-02-23 | 2023-08-31 | Bright Peak Therapeutics Ag | ACTIVABLE IL-18 POLYPEPTIDES |
| CA3244053A1 (en) * | 2022-02-23 | 2023-08-31 | Bright Peak Therapeutics Ag | Modified il-18 polypeptides |
| JP2025509832A (ja) | 2022-03-15 | 2025-04-11 | コンピュジェン リミテッド | Ｉｌ－１８ｂｐアンタゴニスト抗体、並びに癌の治療での単剤療法及び併用療法におけるそれらの使用 |
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| JP2025529313A (ja) * | 2022-09-06 | 2025-09-04 | ティージェイ バイオファーマ （シャンハイ） カンパニー， リミテッド | Ｉｌ－１８バリアントポリペプチド |
| EP4604988A1 (en) * | 2022-10-21 | 2025-08-27 | Diagonal Therapeutics Inc. | Heteromeric agonistic antibodies to il-18 receptor |
| WO2024102693A2 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Il-18-fc fusion proteins |
| CN118141897A (zh) | 2022-12-07 | 2024-06-07 | 广州威溶特医药科技有限公司 | Dr-18和溶瘤痘苗病毒在制备抗肿瘤药物中的应用 |
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| EP4646270A2 (en) * | 2023-01-06 | 2025-11-12 | Alector LLC | Anti-il18 binding protein antibodies and methods of use thereof |
| TW202430560A (zh) * | 2023-01-06 | 2024-08-01 | 美商拉森醫療公司 | 抗ｉｌ－１８ｂｐ抗體 |
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| WO2024251983A1 (en) * | 2023-06-09 | 2024-12-12 | Merck Patent Gmbh | Il-18 mimetics |
| TW202515608A (zh) | 2023-06-26 | 2025-04-16 | 以色列商坎布根有限公司 | Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途 |
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| WO2025041101A1 (en) | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Activatable il-18 immunocytokines and uses thereof |
| US20250188166A1 (en) | 2023-08-23 | 2025-06-12 | Bright Peak Therapeutics Ag | Il-18 polypeptides fused to immune cell antigen specific binding polypeptides and uses thereof |
| WO2025068413A1 (en) | 2023-09-28 | 2025-04-03 | Prokarium Limited | Interleukin 18 variants |
| WO2025085447A1 (en) | 2023-10-17 | 2025-04-24 | Xencor, Inc. | Pd-1 targeted il18-fc fusion proteins |
| CN120093897A (zh) * | 2023-12-04 | 2025-06-06 | 广州威溶特医药科技有限公司 | Dr-18和单纯疱疹病毒在制备抗肿瘤药物中的应用 |
| CN120189493A (zh) | 2023-12-22 | 2025-06-24 | 广州威溶特医药科技有限公司 | Dr-18和m1病毒在制备抗肿瘤药物中的应用 |
| US12134635B1 (en) | 2023-12-29 | 2024-11-05 | Sonnet BioTherapeutics, Inc. | Interleukin 18 (IL-18) variants and fusion proteins comprising same |
| WO2025151273A1 (en) * | 2024-01-08 | 2025-07-17 | Adimab, Llc | Il-18 polypeptides and uses thereof |
| WO2025242835A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of cancer |
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-
2018
- 2018-09-06 WO PCT/US2018/049648 patent/WO2019051015A1/en not_active Ceased
- 2018-09-06 US US16/123,063 patent/US20190070262A1/en not_active Abandoned
- 2018-09-06 IL IL272635A patent/IL272635B2/en unknown
- 2018-09-06 CN CN201880071694.4A patent/CN111315395A/zh active Pending
- 2018-09-06 EP EP18853870.6A patent/EP3678681A4/en active Pending
- 2018-09-06 JP JP2020513648A patent/JP2020533301A/ja active Pending
- 2018-09-06 BR BR112020004389-3A patent/BR112020004389A2/pt unknown
- 2018-09-06 KR KR1020207009724A patent/KR20200066623A/ko not_active Ceased
- 2018-09-06 SG SG11202001384TA patent/SG11202001384TA/en unknown
- 2018-09-06 MX MX2020002542A patent/MX2020002542A/es unknown
- 2018-09-06 AU AU2018330444A patent/AU2018330444B2/en active Active
- 2018-09-06 IL IL305370A patent/IL305370A/en unknown
- 2018-09-06 CA CA3080492A patent/CA3080492A1/en active Pending
-
2022
- 2022-11-15 US US18/055,581 patent/US12343379B2/en active Active
-
2023
- 2023-01-20 US US18/157,385 patent/US20230321192A1/en active Pending
- 2023-03-08 US US18/180,389 patent/US12403180B2/en active Active
- 2023-07-19 ZA ZA2023/07212A patent/ZA202307212B/en unknown
- 2023-08-18 JP JP2023133442A patent/JP2023157959A/ja active Pending
- 2023-11-15 AU AU2023266285A patent/AU2023266285A1/en not_active Abandoned
-
2024
- 2024-04-04 US US18/626,930 patent/US20240325494A1/en active Pending
- 2024-11-08 US US18/941,441 patent/US20250057918A1/en active Pending
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