ITUA20161992A1 - Sumo e suoi utilizzi - Google Patents

Sumo e suoi utilizzi

Info

Publication number
ITUA20161992A1
ITUA20161992A1 ITUA2016A001992A ITUA20161992A ITUA20161992A1 IT UA20161992 A1 ITUA20161992 A1 IT UA20161992A1 IT UA2016A001992 A ITUA2016A001992 A IT UA2016A001992A IT UA20161992 A ITUA20161992 A IT UA20161992A IT UA20161992 A1 ITUA20161992 A1 IT UA20161992A1
Authority
IT
Italy
Prior art keywords
sumo
Prior art date
Application number
ITUA2016A001992A
Other languages
English (en)
Inventor
Luca Colnaghi
Luana Fioriti
Amir Levine
Original Assignee
Plico Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plico Biotech Inc filed Critical Plico Biotech Inc
Priority to ITUA2016A001992A priority Critical patent/ITUA20161992A1/it
Priority to EP17714902.8A priority patent/EP3432909A1/en
Priority to CA3018295A priority patent/CA3018295A1/en
Priority to US16/087,548 priority patent/US20210198327A1/en
Priority to PCT/IB2017/051667 priority patent/WO2017163203A1/en
Publication of ITUA20161992A1 publication Critical patent/ITUA20161992A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1741Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals alpha-Glycoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/473Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used alpha-Glycoproteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ITUA2016A001992A 2016-03-24 2016-03-24 Sumo e suoi utilizzi ITUA20161992A1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITUA2016A001992A ITUA20161992A1 (it) 2016-03-24 2016-03-24 Sumo e suoi utilizzi
EP17714902.8A EP3432909A1 (en) 2016-03-24 2017-03-22 SUMO and uses thereof
CA3018295A CA3018295A1 (en) 2016-03-24 2017-03-22 Sumo and uses thereof
US16/087,548 US20210198327A1 (en) 2016-03-24 2017-03-22 Sumo and uses thereof
PCT/IB2017/051667 WO2017163203A1 (en) 2016-03-24 2017-03-22 SUMO and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A001992A ITUA20161992A1 (it) 2016-03-24 2016-03-24 Sumo e suoi utilizzi

Publications (1)

Publication Number Publication Date
ITUA20161992A1 true ITUA20161992A1 (it) 2017-09-24

Family

ID=56235885

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A001992A ITUA20161992A1 (it) 2016-03-24 2016-03-24 Sumo e suoi utilizzi

Country Status (5)

Country Link
US (1) US20210198327A1 (it)
EP (1) EP3432909A1 (it)
CA (1) CA3018295A1 (it)
IT (1) ITUA20161992A1 (it)
WO (1) WO2017163203A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700106405A1 (it) * 2017-09-22 2019-03-22 Plico Biotech Inc Formulazione per la somministrazione di SUMO2
WO2020192754A1 (en) * 2019-03-28 2020-10-01 The Chinese University Of Hong Kong Sumo peptides for treating neurodegenerative diseases

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235733A1 (en) * 2003-02-27 2004-11-25 Steffan Joan S. Methods and reagents for reducing polyglutamine toxicity
WO2007047950A2 (en) * 2005-10-21 2007-04-26 Caritas St. Elizabeth Medical Center Of Boston, Inc. Use of sumoylation inhibitors for the treatment of neurodegenerative disease
EP2100961A1 (en) * 2008-03-04 2009-09-16 Icon Genetics GmbH Method of protease production in plants
KR20140015997A (ko) * 2012-07-27 2014-02-07 한화케미칼 주식회사 Sumo 단백질과 sim의 결합을 이용한 신규한 이중특이성 결합 복합체 및 그의 용도
WO2014036268A2 (en) * 2012-08-29 2014-03-06 Mount Sinai School Of Medicine Indole derivatives as sumo activators

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040235733A1 (en) * 2003-02-27 2004-11-25 Steffan Joan S. Methods and reagents for reducing polyglutamine toxicity
WO2007047950A2 (en) * 2005-10-21 2007-04-26 Caritas St. Elizabeth Medical Center Of Boston, Inc. Use of sumoylation inhibitors for the treatment of neurodegenerative disease
EP2100961A1 (en) * 2008-03-04 2009-09-16 Icon Genetics GmbH Method of protease production in plants
KR20140015997A (ko) * 2012-07-27 2014-02-07 한화케미칼 주식회사 Sumo 단백질과 sim의 결합을 이용한 신규한 이중특이성 결합 복합체 및 그의 용도
WO2014036268A2 (en) * 2012-08-29 2014-03-06 Mount Sinai School Of Medicine Indole derivatives as sumo activators

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BETTINA DRISALDI ET AL: "SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3", CELL REPORTS, vol. 11, no. 11, 1 June 2015 (2015-06-01), US, pages 1694 - 1702, XP055321338, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2015.04.061 *
CUOMO ORNELLA ET AL: "Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning", STROKE; A JOURNAL OF CEREBRAL CIRCULATION NOV 2004, AMERICAN HEART ASSOCIATION, DALLAS, TX, vol. 47, no. 4, 1 April 2016 (2016-04-01), pages 1085 - 1093, XP009192528, ISSN: 1524-4628 *
KRUMOVA PETRANKA ET AL: "Sumoylation inhibits alpha-synuclein aggregation and toxicity", THE JOURNAL OF CELL BIOLOGY : JCB, THE ROCKEFELLER UNIVERSITY PRESS, US, vol. 194, no. 1, 1 July 2011 (2011-07-01), pages 49 - 60, XP009192529, ISSN: 0021-9525 *
LEE LINDA ET AL: "SUMO and Alzheimer's Dis", NEUROMOLECULAR MEDICINE, HUMANA PRESS, US, vol. 15, no. 4, 25 August 2013 (2013-08-25), pages 720 - 736, XP035359268, ISSN: 1535-1084, [retrieved on 20130825], DOI: 10.1007/S12017-013-8257-7 *

Also Published As

Publication number Publication date
EP3432909A1 (en) 2019-01-30
CA3018295A1 (en) 2017-09-28
WO2017163203A1 (en) 2017-09-28
US20210198327A1 (en) 2021-07-01

Similar Documents

Publication Publication Date Title
FIC20230014I1 (fi) Foslevodopa ja foskarbidopa
DK3448386T3 (da) Isoquinolin-3-ylcarboxamider og fremstilling og anvendelse deraf
DK3627029T3 (da) Manipulationssikret låg
DK3212255T3 (da) Selvorienterende sprøjte og sprøjtegrænseflade
DK3227342T3 (da) Proteinøs heterodimer og anvendelse deraf
DK3152607T3 (da) En antiresonant hulkernefiber
DK3210977T3 (da) Hidtil ukendt aminoalkylbenzothiazepinderivat og anvendelse deraf
MA40933A (fr) Difluorométhyl-aminopyridines et difluorométhyl-aminopyrimidines
BR112016016289A2 (pt) heteroaris e usos dos mesmos
DK3015526T3 (da) Hydrofluorolefinbaseret sammensætning og anvendelse deraf
DK3335532T3 (da) Tandharve
DK3161139T3 (da) Tlr-4-specifikke aptamerer og anvendelser heraf
DK3209773T3 (da) Prolintolerante tripeptidylpeptidaser og anvendelser deraf
DK3128005T3 (da) Sirp-alfa-variantkonstruktioner og anvendelser deraf
MA49905A (fr) Polyesteramines et polyesterquats
DK3672948T3 (da) Pyridinamin-pyridon- og pyrimidinamin-pyridonforbindelser
DE112017006386A5 (de) Schraubarbeitszylinder
DE112017000734A5 (de) Glycolsensor
DK3365321T3 (da) Solabegron-zwitterion og anvendelser deraf
DK3321279T3 (da) Exenatidmodificeringsmiddel og anvendelse deraf
DK3337506T3 (da) Kombinationer og anvendelser deraf
BR112017018932A2 (pt) etv2 e usos do mesmo
DK3189050T3 (da) Antivirale midler og anvendelser deraf
DK3323708T3 (da) Bovfender
DK3263133T3 (da) Pyridinonforbindelse og anvendelse deraf