JP2020529862A5 - - Google Patents

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Publication number
JP2020529862A5
JP2020529862A5 JP2020520425A JP2020520425A JP2020529862A5 JP 2020529862 A5 JP2020529862 A5 JP 2020529862A5 JP 2020520425 A JP2020520425 A JP 2020520425A JP 2020520425 A JP2020520425 A JP 2020520425A JP 2020529862 A5 JP2020529862 A5 JP 2020529862A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
percentage homology
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020520425A
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English (en)
Japanese (ja)
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JP2020529862A (ja
JP7601635B2 (ja
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Priority claimed from PCT/US2018/039147 external-priority patent/WO2019005635A2/en
Publication of JP2020529862A publication Critical patent/JP2020529862A/ja
Publication of JP2020529862A5 publication Critical patent/JP2020529862A5/ja
Priority to JP2023061568A priority Critical patent/JP7490109B2/ja
Application granted granted Critical
Publication of JP7601635B2 publication Critical patent/JP7601635B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020520425A 2017-06-25 2018-06-22 抗pd-1抗体とその作製及び使用方法 Active JP7601635B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023061568A JP7490109B2 (ja) 2017-06-25 2023-04-05 抗pd-1抗体とその作製及び使用方法

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201762524557P 2017-06-25 2017-06-25
US201762524553P 2017-06-25 2017-06-25
US201762524554P 2017-06-25 2017-06-25
US201762524558P 2017-06-25 2017-06-25
US62/524,553 2017-06-25
US62/524,554 2017-06-25
US62/524,557 2017-06-25
US62/524,558 2017-06-25
US201762545603P 2017-08-15 2017-08-15
US62/545,603 2017-08-15
PCT/US2018/039147 WO2019005635A2 (en) 2017-06-25 2018-06-22 ANTI-PD-1 ANTIBODIES AND METHODS OF PREPARATION AND USE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023061568A Division JP7490109B2 (ja) 2017-06-25 2023-04-05 抗pd-1抗体とその作製及び使用方法

Publications (3)

Publication Number Publication Date
JP2020529862A JP2020529862A (ja) 2020-10-15
JP2020529862A5 true JP2020529862A5 (enExample) 2022-01-17
JP7601635B2 JP7601635B2 (ja) 2024-12-17

Family

ID=64742653

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020520425A Active JP7601635B2 (ja) 2017-06-25 2018-06-22 抗pd-1抗体とその作製及び使用方法
JP2023061568A Active JP7490109B2 (ja) 2017-06-25 2023-04-05 抗pd-1抗体とその作製及び使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023061568A Active JP7490109B2 (ja) 2017-06-25 2023-04-05 抗pd-1抗体とその作製及び使用方法

Country Status (5)

Country Link
US (1) US11466084B2 (enExample)
EP (1) EP3645740A4 (enExample)
JP (2) JP7601635B2 (enExample)
CN (1) CN110799537B (enExample)
WO (1) WO2019005635A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6881658B2 (ja) 2019-07-05 2021-06-02 小野薬品工業株式会社 Pd−1/cd3二重特異性タンパク質による血液がん治療
US20220332825A1 (en) 2019-08-08 2022-10-20 Ono Pharmaceutical Co., Ltd. Bispecific protein
MX2023002279A (es) * 2020-08-27 2023-03-10 Shanghai Junshi Biosciences Co Ltd Uso de un anticuerpo anti-pd-1 en el tratamiento del carcinoma nasofaringeo.
TW202241957A (zh) * 2021-02-10 2022-11-01 大陸商上海濟煜醫藥科技有限公司 抗pd-1抗體及其用途
CN116687933B (zh) * 2022-02-28 2025-10-31 中国科学院上海药物研究所 甲氨蝶呤及其药物组合物在肿瘤免疫治疗中的用途
CN120813375A (zh) 2023-01-30 2025-10-17 凯玛布有限公司 抗体
CN119775428B (zh) * 2024-12-12 2025-08-05 广东沃博生物医药科技有限公司 一种免疫细胞的制备方法及其在治疗疾病中的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
CN101899114A (zh) * 2002-12-23 2010-12-01 惠氏公司 抗pd-1抗体及其用途
DK2439273T3 (da) * 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
BR122017025062B8 (pt) * 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
TW201134488A (en) * 2010-03-11 2011-10-16 Ucb Pharma Sa PD-1 antibodies
AU2014309199B2 (en) * 2013-08-20 2018-04-19 Merck Sharp & Dohme Llc Treating cancer with a combination of a PD-1 antagonist and dinaciclib
TWI681969B (zh) * 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
PE20170255A1 (es) * 2014-01-24 2017-03-22 Dana Farber Cancer Inst Inc Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas
BR112017001385B1 (pt) * 2014-07-22 2023-12-05 Cb Therapeutics, Inc. Anticorpo isolado ou fragmento do mesmo que liga a pd-1, uso deste, composição, polinucleotídeo isolado e vetor de expressão
HUE068868T2 (hu) * 2015-07-30 2025-02-28 Macrogenics Inc PD-1-hez kötõdõ molekulák és alkalmazásukra szolgáló eljárások
ES2924402T3 (es) * 2015-10-02 2022-10-06 Symphogen As Anticuerpos anti-PD-1 y composiciones

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