JP2020528888A5 - - Google Patents

Info

Publication number

JP2020528888A5

JP2020528888A5 JP2020502672A JP2020502672A JP2020528888A5 JP 2020528888 A5 JP2020528888 A5 JP 2020528888A5 JP 2020502672 A JP2020502672 A JP 2020502672A JP 2020502672 A JP2020502672 A JP 2020502672A JP 2020528888 A5 JP2020528888 A5 JP 2020528888A5

Authority

JP

Japan

Prior art keywords

composition

iron

salt

iii

use according

Prior art date

2018-07-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 239000000203 mixture Substances 0.000 claims 26
• 229930006000 Sucrose Natural products 0.000 claims 9
• 239000005720 sucrose Substances 0.000 claims 9
• 235000010445 lecithin Nutrition 0.000 claims 8
• 239000000787 lecithin Substances 0.000 claims 8
• -1 sucrose fatty acid ester Chemical class 0.000 claims 8
• VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims 6
• XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 6
• IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 5
• 229920000881 Modified starch Polymers 0.000 claims 5
• 235000014113 dietary fatty acids Nutrition 0.000 claims 5
• 239000000194 fatty acid Substances 0.000 claims 5
• 229930195729 fatty acid Natural products 0.000 claims 5
• 229940067606 lecithin Drugs 0.000 claims 5
• 150000003839 salts Chemical class 0.000 claims 5
• 239000001959 sucrose esters of fatty acids Substances 0.000 claims 5
• TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims 4
• 239000000654 additive Substances 0.000 claims 4
• 159000000003 magnesium salts Chemical class 0.000 claims 4
• 208000005475 Vascular calcification Diseases 0.000 claims 3
• 229910052742 iron Inorganic materials 0.000 claims 3
• 239000001095 magnesium carbonate Substances 0.000 claims 3
• 229910000021 magnesium carbonate Inorganic materials 0.000 claims 3
• 229930003231 vitamin Natural products 0.000 claims 3
• 229940088594 vitamin Drugs 0.000 claims 3
• 239000011782 vitamin Substances 0.000 claims 3
• 235000013343 vitamin Nutrition 0.000 claims 3
• PFRQBZFETXBLTP-RCIYGOBDSA-N 2-[(2e,6e,10e,14e,18e)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3-methyl-1,4-dihydronaphthalene-1,4-dione Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)=C(C)C(=O)C2=C1 PFRQBZFETXBLTP-RCIYGOBDSA-N 0.000 claims 2
• 230000000996 additive effect Effects 0.000 claims 2
• 206010002906 aortic stenosis Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 208000035475 disorder Diseases 0.000 claims 2
• 235000013305 food Nutrition 0.000 claims 2
• ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims 2
• 229910001629 magnesium chloride Inorganic materials 0.000 claims 2
• 239000000395 magnesium oxide Substances 0.000 claims 2
• CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims 2
• AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical group [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 claims 2
• 230000000069 prophylactic effect Effects 0.000 claims 2
• 238000002560 therapeutic procedure Methods 0.000 claims 2
• 206010065558 Aortic arteriosclerosis Diseases 0.000 claims 1
• 206010007559 Cardiac failure congestive Diseases 0.000 claims 1
• 206010007572 Cardiac hypertrophy Diseases 0.000 claims 1
• 208000006029 Cardiomegaly Diseases 0.000 claims 1
• 206010019280 Heart failures Diseases 0.000 claims 1
• 206010020772 Hypertension Diseases 0.000 claims 1
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
• 229930003448 Vitamin K Natural products 0.000 claims 1
• 201000001962 aortic atherosclerosis Diseases 0.000 claims 1
• 208000020832 chronic kidney disease Diseases 0.000 claims 1
• 206010012601 diabetes mellitus Diseases 0.000 claims 1
• CADNYOZXMIKYPR-UHFFFAOYSA-B ferric pyrophosphate Chemical compound [Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O CADNYOZXMIKYPR-UHFFFAOYSA-B 0.000 claims 1
• 208000031225 myocardial ischemia Diseases 0.000 claims 1
• 230000003647 oxidation Effects 0.000 claims 1
• 238000007254 oxidation reaction Methods 0.000 claims 1
• SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 claims 1
• 239000000126 substance Substances 0.000 claims 1
• 235000019168 vitamin K Nutrition 0.000 claims 1
• 239000011712 vitamin K Substances 0.000 claims 1
• 150000003721 vitamin K derivatives Chemical group 0.000 claims 1
• 150000003722 vitamin derivatives Chemical class 0.000 claims 1
• 229940046010 vitamin k Drugs 0.000 claims 1