|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
JPS5896026A
(ja)
|
1981-10-30 |
1983-06-07 |
Nippon Chemiphar Co Ltd |
新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤
|
|
US4609546A
(en)
|
1982-06-24 |
1986-09-02 |
Japan Chemical Research Co., Ltd. |
Long-acting composition
|
|
US4681581A
(en)
|
1983-12-05 |
1987-07-21 |
Coates Fredrica V |
Adjustable size diaper and folding method therefor
|
|
US4766106A
(en)
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
|
US4735210A
(en)
|
1985-07-05 |
1988-04-05 |
Immunomedics, Inc. |
Lymphographic and organ imaging method and kit
|
|
US5776093A
(en)
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
US5101827A
(en)
|
1985-07-05 |
1992-04-07 |
Immunomedics, Inc. |
Lymphographic and organ imaging method and kit
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5750172A
(en)
|
1987-06-23 |
1998-05-12 |
Pharming B.V. |
Transgenic non human mammal milk
|
|
US5648471A
(en)
|
1987-12-03 |
1997-07-15 |
Centocor, Inc. |
One vial method for labeling antibodies with Technetium-99m
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
JP3070763B2
(ja)
|
1989-08-09 |
2000-07-31 |
ロメッド インコーポレイティド |
テクネチウムまたはレニウムでの抗体または他のタンパク質の直接放射能標識
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
US5101990A
(en)
|
1990-03-23 |
1992-04-07 |
Continental Pet Technologies, Inc. |
Stretch blow molded oblong or oval container
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
WO1992003918A1
(en)
|
1990-08-29 |
1992-03-19 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
WO1992022645A1
(en)
|
1991-06-14 |
1992-12-23 |
Genpharm International, Inc. |
Transgenic immunodeficient non-human animals
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
EP0593592B1
(en)
|
1991-07-08 |
1998-03-25 |
The University Of Massachusetts At Amherst |
Thermotropic liquid crystal segmented block copolymer
|
|
EP0746609A4
(en)
|
1991-12-17 |
1997-12-17 |
Genpharm Int |
NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES
|
|
DK0804070T3
(da)
|
1993-03-09 |
2000-08-07 |
Genzyme Corp |
Fremgangsmåde til isolering af proteiner fra mælk
|
|
EP0754225A4
(en)
|
1993-04-26 |
2001-01-31 |
Genpharm Int |
HETEROLOGIC ANTIBODY-PRODUCING TRANSGENIC NON-HUMAN ANIMALS
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US6077835A
(en)
|
1994-03-23 |
2000-06-20 |
Case Western Reserve University |
Delivery of compacted nucleic acid to cells
|
|
KR970029803A
(ko)
|
1995-11-03 |
1997-06-26 |
김광호 |
반도체 메모리장치의 프리차지 회로
|
|
CA2361421A1
(en)
|
1999-02-03 |
2000-08-10 |
Biosante Pharmaceuticals, Inc. |
Therapeutic calcium phosphate particles and methods of manufacture and use
|
|
US6281005B1
(en)
|
1999-05-14 |
2001-08-28 |
Copernicus Therapeutics, Inc. |
Automated nucleic acid compaction device
|
|
JP2003516718A
(ja)
|
1999-07-29 |
2003-05-20 |
メダレックス インク |
ＨＥＲ２／ｎｅｕに対するヒトモノクローナル抗体
|
|
MXPA02001911A
(es)
|
1999-08-24 |
2003-07-21 |
Medarex Inc |
Anticuerpos ctla-4 humanos y sus usos.
|
|
ES2405944T3
(es)
|
2000-11-30 |
2013-06-04 |
Medarex, Inc. |
Ácidos nucleicos que codifican las secuencias de inmunoglobulina humana reorganizadas a partir de ratones transcromoscómicos transgénicos
zadas
|
|
EP1539233B1
(en)
|
2001-07-12 |
2011-04-27 |
FOOTE, Jefferson |
Super humanized antibodies
|
|
US8066997B2
(en)
|
2002-12-20 |
2011-11-29 |
Anders Nykjaer |
Modulation of activity of neurotrophins
|
|
EP1973576B1
(en)
|
2005-11-28 |
2019-05-15 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
|
WO2008076262A2
(en)
|
2006-12-15 |
2008-06-26 |
Merck & Co., Inc. |
Receptor for amyloid beta and uses thereof
|
|
PL3225251T3
(pl)
|
2006-12-21 |
2020-06-29 |
H. Lundbeck A/S |
Modulacja aktywności proneurotrofin
|
|
EP2185692A4
(en)
|
2007-08-10 |
2012-05-02 |
Medarex Inc |
HCO32 AND HCO27 AND RELATED EXAMPLES
|
|
US20100324127A1
(en)
*
|
2008-01-16 |
2010-12-23 |
Kay Denis G |
Treating neurodegenerative diseases with progranulin
|
|
EP2274327B1
(en)
|
2008-04-27 |
2019-03-27 |
H. Lundbeck A/S |
Crystal structure of human sortilin and uses thereof for identifying ligands to sortilin
|
|
WO2009154995A2
(en)
*
|
2008-05-27 |
2009-12-23 |
Kyowa Hakko Kirin Co., Ltd. |
Interleukin 10 receptor (il-10r) antibodies and methods of use
|
|
US20120039865A1
(en)
|
2008-08-19 |
2012-02-16 |
Yale University |
Identification of sortilin as a neuronal receptor for the frontotemporal dementia protein, progranulin
|
|
US8703125B2
(en)
|
2008-12-19 |
2014-04-22 |
H. Lundbeck A/S |
Modulation of the Vps10p-domain receptor family for the treatment of mental and behavioural disorders
|
|
US9822366B2
(en)
|
2012-11-02 |
2017-11-21 |
The Brigham And Women's Hospital, Inc. |
Sortilin 1 is a novel inducer of vascular calcification
|
|
WO2015143300A1
(en)
*
|
2014-03-21 |
2015-09-24 |
The Board Of Regents Of The University Of Texas System |
Isoxazole treatments for frontotemporal dementia
|
|
US10428158B2
(en)
*
|
2014-03-27 |
2019-10-01 |
Dyax Corp. |
Compositions and methods for treatment of diabetic macular edema
|
|
PT3280441T
(pt)
*
|
2015-04-07 |
2021-11-30 |
Alector Llc |
Anticorpos anti-sortilina e métodos para a sua utilização
|
|
GB201512215D0
(en)
|
2015-07-13 |
2015-08-19 |
Lundbeck & Co As H |
Agents,uses and methods
|
|
PE20191741A1
(es)
*
|
2017-04-05 |
2019-12-12 |
Symphogen As |
Terapias combinadas dirigidas a pd-1, tim-3, y lag-3
|
|
SI3618928T1
(sl)
*
|
2018-07-13 |
2023-04-28 |
Alector Llc |
Protitelesa proti sortilinu in postopki za uporabo le-teh
|
|
CN113151432A
(zh)
*
|
2020-04-14 |
2021-07-23 |
郁金泰 |
神经退行性疾病检测和治疗的新靶标
|
