JP2020525012A5 - - Google Patents
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- JP2020525012A5 JP2020525012A5 JP2019571258A JP2019571258A JP2020525012A5 JP 2020525012 A5 JP2020525012 A5 JP 2020525012A5 JP 2019571258 A JP2019571258 A JP 2019571258A JP 2019571258 A JP2019571258 A JP 2019571258A JP 2020525012 A5 JP2020525012 A5 JP 2020525012A5
- Authority
- JP
- Japan
- Prior art keywords
- ecolin
- phage
- genes
- genome
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023093143A JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762523202P | 2017-06-21 | 2017-06-21 | |
| US201762523225P | 2017-06-21 | 2017-06-21 | |
| US62/523,225 | 2017-06-21 | ||
| US62/523,202 | 2017-06-21 | ||
| US201762552785P | 2017-08-31 | 2017-08-31 | |
| US201762552829P | 2017-08-31 | 2017-08-31 | |
| US62/552,829 | 2017-08-31 | ||
| US62/552,785 | 2017-08-31 | ||
| US201862614213P | 2018-01-05 | 2018-01-05 | |
| US62/614,213 | 2018-01-05 | ||
| US201862624299P | 2018-01-31 | 2018-01-31 | |
| US62/624,299 | 2018-01-31 | ||
| PCT/US2018/038840 WO2018237198A1 (en) | 2017-06-21 | 2018-06-21 | Bacteria for the treatment of disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093143A Division JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020525012A JP2020525012A (ja) | 2020-08-27 |
| JP2020525012A5 true JP2020525012A5 (enExample) | 2021-07-26 |
| JP7358245B2 JP7358245B2 (ja) | 2023-10-10 |
Family
ID=62909623
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571258A Active JP7358245B2 (ja) | 2017-06-21 | 2018-06-21 | 障害の処置のための細菌 |
| JP2023093143A Active JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A Pending JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023093143A Active JP7639056B2 (ja) | 2017-06-21 | 2023-06-06 | 障害の処置のための細菌 |
| JP2025025000A Pending JP2025087727A (ja) | 2017-06-21 | 2025-02-19 | 障害の処置のための細菌 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11879123B2 (enExample) |
| EP (1) | EP3642221A1 (enExample) |
| JP (3) | JP7358245B2 (enExample) |
| CN (1) | CN111655841A (enExample) |
| AU (2) | AU2018290278B2 (enExample) |
| CA (1) | CA3066085A1 (enExample) |
| IL (1) | IL271085B2 (enExample) |
| WO (1) | WO2018237198A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| EP3682008A4 (en) | 2017-09-14 | 2020-12-09 | University of Massachusetts | GENETICALLY MODIFIED MICRO-ORGANISMS AND THEIR METHODS OF USE |
| CN108048342B (zh) * | 2017-10-26 | 2021-06-04 | 中国农业大学 | 一种耐压益生菌及其食品和制备方法 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| KR20220003030A (ko) | 2019-04-29 | 2022-01-07 | 신로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 살아 있는 세포 계수 기술에 의한 유전적으로 조작된 미생물의 계수 |
| EP3962506A4 (en) * | 2019-05-03 | 2022-07-13 | University Of Massachusetts | GENETICALLY MODIFIED MICROORGANISMS AND METHODS OF USE |
| CN114008070A (zh) * | 2019-06-21 | 2022-02-01 | 因思科瑞普特公司 | 导致大肠杆菌赖氨酸产量增加的全基因组合理设计的突变 |
| CN110592057B (zh) * | 2019-09-27 | 2022-01-28 | 昆明理工大学 | 嵌合裂解酶ILTphg和编码此酶的多核苷酸 |
| WO2021127648A1 (en) * | 2019-12-19 | 2021-06-24 | Auburn University | Microbial ester production |
| US20230092431A1 (en) * | 2020-01-14 | 2023-03-23 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| CN111235169A (zh) * | 2020-02-03 | 2020-06-05 | 昆明理工大学 | 一种GTP环化水解酶I基因folE及应用 |
| WO2021173808A1 (en) * | 2020-02-25 | 2021-09-02 | Synlogic Operating Company, Inc. | Recombinant bacteria engineered to treat diseases associated with uric acid and methods of use thereof |
| BR112022018571A2 (pt) | 2020-03-20 | 2022-11-01 | Synlogic Operating Co Inc | Microrganismos manipulados para reduzir a hiperfenilalaninemia |
| US20220031771A1 (en) * | 2020-07-31 | 2022-02-03 | Iowa State University Research Foundation, Inc. | Microencapsulated and chromosome integrated compositions for l-dopa microbiome therapy |
| CN111876400B (zh) * | 2020-08-06 | 2022-05-24 | 昆明理工大学 | 一种常温裂解酶Sly和编码此酶的多核苷酸 |
| AU2021393455A1 (en) | 2020-12-02 | 2023-06-29 | Synlogic Operating Company, Inc. | Engineered microorganisms |
| CN116847860A (zh) * | 2020-12-31 | 2023-10-03 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
| CN112662607A (zh) * | 2021-01-07 | 2021-04-16 | 上海陶宇晟生物技术有限责任公司 | 具备表面展示苯丙氨酸解氨酶的工程益生菌 |
| WO2022204406A1 (en) * | 2021-03-24 | 2022-09-29 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders in which oxalate is detrimental |
| CN113789276B (zh) * | 2021-09-15 | 2023-05-12 | 千宠堂(福建)生物科技有限公司 | 一株产β-烟酰胺单核苷酸的植物乳杆菌及其应用 |
| WO2023044479A1 (en) | 2021-09-17 | 2023-03-23 | Synlogic Operating Company, Inc. | Methods for reducing hyperphenylalaninemia |
| CN116555063B (zh) * | 2022-01-27 | 2025-08-08 | 中国海洋大学 | 动物双歧杆菌f1-7在降解苯丙氨酸中的应用 |
| CN116179452A (zh) * | 2022-07-11 | 2023-05-30 | 山东第一医科大学(山东省医学科学院) | 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用 |
| JP2025534764A (ja) | 2022-10-17 | 2025-10-17 | シンロジック オペレーティング カンパニー インコーポレイテッド | 高フェニルアラニン血症を軽減するためのフェニルアラニンアンモニアリアーゼ、フェニルアラニントランスポーターおよびｌ－アミノ酸デアミナーゼを発現する組み換え細菌 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| CN1154845A (zh) | 1996-09-09 | 1997-07-23 | 首都医学院附属北京红十字朝阳医院 | 能表达活性苯丙氨酸脱氨酶的基因工程菌口服制剂 |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6203797B1 (en) | 1998-01-06 | 2001-03-20 | Stephen C. Perry | Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome |
| EP1034787A1 (en) | 1999-03-11 | 2000-09-13 | Société des Produits Nestlé S.A. | Lactobacillus strains preventing diarrhea caused by pathogenic bacteria |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| US7731976B2 (en) | 2003-08-29 | 2010-06-08 | Cobb And Company, Llp | Treatment of irritable bowel syndrome using probiotic composition |
| JP4452914B2 (ja) | 2003-09-08 | 2010-04-21 | 味の素株式会社 | 新規トランスポータタンパク質 |
| CN101068919B (zh) * | 2004-11-30 | 2011-08-10 | Aeras全球Tb疫苗基金会 | 适用于产生和制备重组双链rna核壳的细菌包装菌株及其用途 |
| TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
| US9084434B2 (en) | 2006-09-27 | 2015-07-21 | Little Calumet Holdings Llc | Probiotic oral dosage forms |
| US20100297249A1 (en) | 2007-07-05 | 2010-11-25 | North-West University | Enhancement of the efficacy of therapeutic proteins |
| CN101586111B (zh) | 2008-05-22 | 2012-03-07 | 北京三元基因工程有限公司 | 一种活性乳酸乳球菌制品的制备方法 |
| EP2344626B1 (en) | 2008-09-29 | 2017-03-29 | Intrexon Actobiotics NV | Reduced colonization of microbes at the mucosa |
| WO2011080505A2 (en) * | 2009-12-28 | 2011-07-07 | Bigdna Ltd | Method of growing phage for commercial use |
| WO2011106874A1 (en) | 2010-03-02 | 2011-09-09 | Functional Technologies Corp. | Functional enhancement of microorganisms to minimize production of acrylamide |
| US8129170B1 (en) | 2010-12-06 | 2012-03-06 | E.I. Du Pont De Nemours And Company | Recombinant bacteria having the ability to metabolize sucrose |
| US9409950B2 (en) | 2010-12-23 | 2016-08-09 | Biogen Ma Inc. | Linker peptides and polypeptides comprising same |
| US9017961B2 (en) | 2012-03-05 | 2015-04-28 | E.I. Du Pont De Nemours And Company | Recombinant bacteria comprising novel sucrose transporters |
| CN104487581B (zh) | 2012-06-22 | 2021-05-28 | 菲特吉恩公司 | 用于苯乙烯合成的酶和方法 |
| CA2880620A1 (en) | 2012-07-27 | 2014-01-30 | University Of North Texas | Genetically modified probiotic for the treatment of phenylketonuria (pku) disease |
| US20150246085A1 (en) | 2012-11-01 | 2015-09-03 | The Sydney Children's Hospital Network (Randwick & Westmead) | Genetically-Modified Probiotic for Treatment of Phenylketonuria |
| WO2014138324A1 (en) | 2013-03-07 | 2014-09-12 | The General Hospital Corporation | Compositions and methods for bacterial delivery of polypeptides |
| BR112017011923A2 (pt) | 2014-12-05 | 2018-02-27 | Synlogic Inc | bactéria modificada para tratar doenças associadas com hiperamonemia |
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| JP7095993B2 (ja) | 2015-03-02 | 2022-07-05 | シンロジック オペレーティング カンパニー インコーポレイテッド | 消化管炎症低下および／または消化管粘膜バリア強化の利益を享受する疾患処置のために操作された細菌 |
| EP3294757B1 (en) | 2015-05-13 | 2023-12-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| EP3307870B1 (en) | 2015-06-10 | 2023-08-02 | Synlogic Operating Company, Inc. | Bacteria engineered to treat disorders involving the catabolism of a branched chain amino acid |
| WO2016210373A2 (en) | 2015-06-24 | 2016-12-29 | Synlogic, Inc. | Recombinant bacteria engineered for biosafety, pharmaceutical compositions, and methods of use thereof |
| EP3377518B1 (en) | 2015-11-16 | 2022-04-13 | Synlogic Operating Company, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| US11723932B2 (en) | 2016-01-11 | 2023-08-15 | Synlogic Operating Company, Inc. | Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells |
-
2018
- 2018-06-21 AU AU2018290278A patent/AU2018290278B2/en active Active
- 2018-06-21 IL IL271085A patent/IL271085B2/en unknown
- 2018-06-21 JP JP2019571258A patent/JP7358245B2/ja active Active
- 2018-06-21 CA CA3066085A patent/CA3066085A1/en active Pending
- 2018-06-21 US US16/621,792 patent/US11879123B2/en active Active
- 2018-06-21 WO PCT/US2018/038840 patent/WO2018237198A1/en not_active Ceased
- 2018-06-21 EP EP18740709.3A patent/EP3642221A1/en active Pending
- 2018-06-21 CN CN201880055641.3A patent/CN111655841A/zh active Pending
-
2023
- 2023-03-01 AU AU2023201271A patent/AU2023201271A1/en active Pending
- 2023-06-06 JP JP2023093143A patent/JP7639056B2/ja active Active
- 2023-11-17 US US18/512,389 patent/US20240368531A1/en active Pending
-
2025
- 2025-02-19 JP JP2025025000A patent/JP2025087727A/ja active Pending
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