CN111655841A - 用于治疗紊乱的细菌 - Google Patents

用于治疗紊乱的细菌 Download PDF

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Publication number
CN111655841A
CN111655841A CN201880055641.3A CN201880055641A CN111655841A CN 111655841 A CN111655841 A CN 111655841A CN 201880055641 A CN201880055641 A CN 201880055641A CN 111655841 A CN111655841 A CN 111655841A
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ecolin
bacterium
phage
genes
bacteriophage
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Chinese (zh)
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迪安·法尔勃
亚当·B·费希尔
文森特·M·伊莎贝拉
乔纳森·W·科图拉
大卫·卢布科维茨
保罗·F·米勒
伊夫·米列特
莎拉·伊丽莎白·罗伊
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Synchronic Operation Co
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Synchronic Operation Co
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    • C12N1/20—Bacteria; Culture media therefor
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A—HUMAN NECESSITIES
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N2795/00—Bacteriophages
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    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201880055641.3A 2017-06-21 2018-06-21 用于治疗紊乱的细菌 Pending CN111655841A (zh)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201762523202P 2017-06-21 2017-06-21
US201762523225P 2017-06-21 2017-06-21
US62/523,225 2017-06-21
US62/523,202 2017-06-21
US201762552785P 2017-08-31 2017-08-31
US201762552829P 2017-08-31 2017-08-31
US62/552,829 2017-08-31
US62/552,785 2017-08-31
US201862614213P 2018-01-05 2018-01-05
US62/614,213 2018-01-05
US201862624299P 2018-01-31 2018-01-31
US62/624,299 2018-01-31
PCT/US2018/038840 WO2018237198A1 (en) 2017-06-21 2018-06-21 Bacteria for the treatment of disorders

Publications (1)

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CN111655841A true CN111655841A (zh) 2020-09-11

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US (2) US11879123B2 (enExample)
EP (1) EP3642221A1 (enExample)
JP (3) JP7358245B2 (enExample)
CN (1) CN111655841A (enExample)
AU (2) AU2018290278B2 (enExample)
CA (1) CA3066085A1 (enExample)
IL (1) IL271085B2 (enExample)
WO (1) WO2018237198A1 (enExample)

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CN110592057A (zh) * 2019-09-27 2019-12-20 昆明理工大学 嵌合裂解酶ILTphg和编码此酶的多核苷酸
CN111235169A (zh) * 2020-02-03 2020-06-05 昆明理工大学 一种GTP环化水解酶I基因folE及应用
CN111876400A (zh) * 2020-08-06 2020-11-03 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN112662607A (zh) * 2021-01-07 2021-04-16 上海陶宇晟生物技术有限责任公司 具备表面展示苯丙氨酸解氨酶的工程益生菌
CN116179452A (zh) * 2022-07-11 2023-05-30 山东第一医科大学(山东省医学科学院) 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用
CN116555063A (zh) * 2022-01-27 2023-08-08 中国海洋大学 动物双歧杆菌f1-7在降解苯丙氨酸中的应用

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CN108048342B (zh) * 2017-10-26 2021-06-04 中国农业大学 一种耐压益生菌及其食品和制备方法
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KR20220003030A (ko) 2019-04-29 2022-01-07 신로직 오퍼레이팅 컴퍼니, 인코포레이티드 살아 있는 세포 계수 기술에 의한 유전적으로 조작된 미생물의 계수
EP3962506A4 (en) * 2019-05-03 2022-07-13 University Of Massachusetts GENETICALLY MODIFIED MICROORGANISMS AND METHODS OF USE
CN114008070A (zh) * 2019-06-21 2022-02-01 因思科瑞普特公司 导致大肠杆菌赖氨酸产量增加的全基因组合理设计的突变
WO2021127648A1 (en) * 2019-12-19 2021-06-24 Auburn University Microbial ester production
US20230092431A1 (en) * 2020-01-14 2023-03-23 Synlogic Operating Company, Inc. Bacteria engineered to treat disorders in which oxalate is detrimental
WO2021173808A1 (en) * 2020-02-25 2021-09-02 Synlogic Operating Company, Inc. Recombinant bacteria engineered to treat diseases associated with uric acid and methods of use thereof
BR112022018571A2 (pt) 2020-03-20 2022-11-01 Synlogic Operating Co Inc Microrganismos manipulados para reduzir a hiperfenilalaninemia
US20220031771A1 (en) * 2020-07-31 2022-02-03 Iowa State University Research Foundation, Inc. Microencapsulated and chromosome integrated compositions for l-dopa microbiome therapy
AU2021393455A1 (en) 2020-12-02 2023-06-29 Synlogic Operating Company, Inc. Engineered microorganisms
CN116847860A (zh) * 2020-12-31 2023-10-03 同生运营公司 经工程化以减轻高苯丙氨酸血症的微生物
WO2022204406A1 (en) * 2021-03-24 2022-09-29 Synlogic Operating Company, Inc. Bacteria engineered to treat disorders in which oxalate is detrimental
CN113789276B (zh) * 2021-09-15 2023-05-12 千宠堂(福建)生物科技有限公司 一株产β-烟酰胺单核苷酸的植物乳杆菌及其应用
WO2023044479A1 (en) 2021-09-17 2023-03-23 Synlogic Operating Company, Inc. Methods for reducing hyperphenylalaninemia
JP2025534764A (ja) 2022-10-17 2025-10-17 シンロジック オペレーティング カンパニー インコーポレイテッド 高フェニルアラニン血症を軽減するためのフェニルアラニンアンモニアリアーゼ、フェニルアラニントランスポーターおよびｌ－アミノ酸デアミナーゼを発現する組み換え細菌

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110592057A (zh) * 2019-09-27 2019-12-20 昆明理工大学 嵌合裂解酶ILTphg和编码此酶的多核苷酸
CN110592057B (zh) * 2019-09-27 2022-01-28 昆明理工大学 嵌合裂解酶ILTphg和编码此酶的多核苷酸
CN111235169A (zh) * 2020-02-03 2020-06-05 昆明理工大学 一种GTP环化水解酶I基因folE及应用
CN111876400A (zh) * 2020-08-06 2020-11-03 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN111876400B (zh) * 2020-08-06 2022-05-24 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN112662607A (zh) * 2021-01-07 2021-04-16 上海陶宇晟生物技术有限责任公司 具备表面展示苯丙氨酸解氨酶的工程益生菌
WO2022148362A1 (zh) * 2021-01-07 2022-07-14 上海陶宇晟生物技术有限责任公司 具备表面展示苯丙氨酸解氨酶的工程益生菌
CN116555063A (zh) * 2022-01-27 2023-08-08 中国海洋大学 动物双歧杆菌f1-7在降解苯丙氨酸中的应用
CN116555063B (zh) * 2022-01-27 2025-08-08 中国海洋大学 动物双歧杆菌f1-7在降解苯丙氨酸中的应用
CN116179452A (zh) * 2022-07-11 2023-05-30 山东第一医科大学(山东省医学科学院) 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用

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