JP2020512373A5 - - Google Patents
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- Publication number
- JP2020512373A5 JP2020512373A5 JP2019553478A JP2019553478A JP2020512373A5 JP 2020512373 A5 JP2020512373 A5 JP 2020512373A5 JP 2019553478 A JP2019553478 A JP 2019553478A JP 2019553478 A JP2019553478 A JP 2019553478A JP 2020512373 A5 JP2020512373 A5 JP 2020512373A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- amine
- phenyl
- compound
- benzodiazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCCC(C*=CC)C(C)(C(C)C)NC Chemical compound CCCC(C*=CC)C(C)(C(C)C)NC 0.000 description 2
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022082769A JP7589191B2 (ja) | 2017-03-31 | 2022-05-20 | 新規の阻害剤 |
| JP2024107135A JP2024153639A (ja) | 2017-03-31 | 2024-07-03 | 新規の阻害剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1705263.0 | 2017-03-31 | ||
| GBGB1705263.0A GB201705263D0 (en) | 2017-03-31 | 2017-03-31 | Novel inhibitors |
| PCT/EP2018/058391 WO2018178384A1 (en) | 2017-03-31 | 2018-04-03 | Novel inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022082769A Division JP7589191B2 (ja) | 2017-03-31 | 2022-05-20 | 新規の阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020512373A JP2020512373A (ja) | 2020-04-23 |
| JP2020512373A5 true JP2020512373A5 (https=) | 2021-05-20 |
| JP7674811B2 JP7674811B2 (ja) | 2025-05-12 |
Family
ID=58682483
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019553478A Active JP7674811B2 (ja) | 2017-03-31 | 2018-04-03 | 新規の阻害剤 |
| JP2022082769A Active JP7589191B2 (ja) | 2017-03-31 | 2022-05-20 | 新規の阻害剤 |
| JP2024107135A Pending JP2024153639A (ja) | 2017-03-31 | 2024-07-03 | 新規の阻害剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022082769A Active JP7589191B2 (ja) | 2017-03-31 | 2022-05-20 | 新規の阻害剤 |
| JP2024107135A Pending JP2024153639A (ja) | 2017-03-31 | 2024-07-03 | 新規の阻害剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11339152B2 (https=) |
| EP (1) | EP3601269A1 (https=) |
| JP (3) | JP7674811B2 (https=) |
| KR (2) | KR20250002689A (https=) |
| CN (2) | CN110719910B (https=) |
| AU (2) | AU2018246382C1 (https=) |
| CA (2) | CA3221839A1 (https=) |
| EA (1) | EA201992120A1 (https=) |
| GB (1) | GB201705263D0 (https=) |
| IL (3) | IL297534A (https=) |
| MX (2) | MX2019011544A (https=) |
| WO (1) | WO2018178384A1 (https=) |
| ZA (1) | ZA201905811B (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2536650A (en) | 2015-03-24 | 2016-09-28 | Augmedics Ltd | Method and system for combining video-based and optic-based augmented reality in a near eye display |
| US12521201B2 (en) | 2017-12-07 | 2026-01-13 | Augmedics Ltd. | Spinous process clamp |
| US12458411B2 (en) | 2017-12-07 | 2025-11-04 | Augmedics Ltd. | Spinous process clamp |
| EP3787543A4 (en) | 2018-05-02 | 2022-01-19 | Augmedics Ltd. | REGISTRATION OF A FIDUCIAL MARKER FOR AN AUGMENTED REALITY SYSTEM |
| CR20210163A (es) * | 2018-10-05 | 2021-06-24 | Pfizer | Inhibidores de pde4 que contienen boro |
| US11766296B2 (en) | 2018-11-26 | 2023-09-26 | Augmedics Ltd. | Tracking system for image-guided surgery |
| WO2020142764A1 (en) * | 2019-01-06 | 2020-07-09 | Psomagen Inc. | Htra inhibitors and caga inhibitors and use thereof |
| US11980506B2 (en) | 2019-07-29 | 2024-05-14 | Augmedics Ltd. | Fiducial marker |
| US12178666B2 (en) | 2019-07-29 | 2024-12-31 | Augmedics Ltd. | Fiducial marker |
| US11382712B2 (en) | 2019-12-22 | 2022-07-12 | Augmedics Ltd. | Mirroring in image guided surgery |
| AU2021208943B2 (en) | 2020-01-17 | 2023-10-05 | Daegu-Gyeongbuk Medical Innovation Foundation | Novel compound, preparation method thereof, and use thereof |
| KR102433502B1 (ko) * | 2020-01-17 | 2022-08-18 | 재단법인 대구경북첨단의료산업진흥재단 | 신규 화합물, 이의 제조방법 및 이의 용도 |
| US11389252B2 (en) | 2020-06-15 | 2022-07-19 | Augmedics Ltd. | Rotating marker for image guided surgery |
| US12502163B2 (en) | 2020-09-09 | 2025-12-23 | Augmedics Ltd. | Universal tool adapter for image-guided surgery |
| US12239385B2 (en) | 2020-09-09 | 2025-03-04 | Augmedics Ltd. | Universal tool adapter |
| WO2022086920A1 (en) * | 2020-10-20 | 2022-04-28 | Blacksmith Medicines, Inc. | Glutaminyl-peptide cyclotransferase like (qpctl) protein inhibitors and uses thereof |
| AR124297A1 (es) * | 2020-12-10 | 2023-03-15 | Bayer Ag | Ácidos pirazol piperidin carboxílicos sustituidos |
| US11896445B2 (en) | 2021-07-07 | 2024-02-13 | Augmedics Ltd. | Iliac pin and adapter |
| US12150821B2 (en) | 2021-07-29 | 2024-11-26 | Augmedics Ltd. | Rotating marker and adapter for image-guided surgery |
| US12475662B2 (en) | 2021-08-18 | 2025-11-18 | Augmedics Ltd. | Stereoscopic display and digital loupe for augmented-reality near-eye display |
| CN117567435A (zh) * | 2022-01-30 | 2024-02-20 | 上海市第十人民医院 | 谷氨酰胺环化酶抑制剂及其应用 |
| WO2023205173A1 (en) * | 2022-04-20 | 2023-10-26 | Blacksmith Medicines, Inc. | Substituted piperidines and substituted tetrahydropyridines as immune-modulating compounds |
| WO2023203521A1 (en) | 2022-04-21 | 2023-10-26 | Augmedics Ltd. | Systems and methods for medical image visualization |
| CN114560817B (zh) * | 2022-04-25 | 2022-10-25 | 北京大学第三医院（北京大学第三临床医学院） | 一种用于抑制纤维化的小分子药物及其应用 |
| AR130003A1 (es) | 2022-08-03 | 2024-10-23 | Boehringer Ingelheim Int | Derivados de piperidinilpiridinilcarbonitrilo como inhibidores de glutaminil-péptido ciclotransferasa y proteína tipo glutaminil-péptido ciclotransferasa |
| JP2025531829A (ja) | 2022-09-13 | 2025-09-25 | オーグメディックス リミテッド | 画像誘導医療介入のための拡張現実アイウェア |
| CN120379972A (zh) * | 2022-12-20 | 2025-07-25 | 深圳湾实验室 | 一种靶向usp1的小分子抑制剂及其应用 |
| KR20250121039A (ko) | 2022-12-22 | 2025-08-11 | 베링거 인겔하임 인터내셔날 게엠베하 | 글루타미닐-펩타이드 사이클로트랜스퍼라제 및 글루타미닐-펩타이드 사이클로트랜스퍼라제 유사 단백질의 억제제로서 페닐피페리딘 유도체 |
| CR20250377A (es) | 2023-03-13 | 2025-11-19 | Boehringer Ingelheim Int | Derivados de fenilpiperidina como inhibidores de la glutaminil-péptido ciclotransferasa y proteína similar a glutaminil-péptido ciclotransferasa |
| IL326207A (en) | 2023-08-04 | 2026-03-01 | Boehringer Ingelheim Int | History of piperidinylpyridinylcarbonitrile as inhibitors of glutaminyl-peptide cyclotransferase and glutaminyl-peptide cyclotransferase-like protein |
| US20250059166A1 (en) | 2023-08-04 | 2025-02-20 | Boehringer Ingelheim International Gmbh | Piperidinylpyridinylcarbonitrile derivatives as inhibitors of glutaminyl-peptide cyclotransferase and glutaminyl-peptide cyclotransferase like protein |
| IL326386A (en) | 2023-08-14 | 2026-04-01 | Boehringer Ingelheim Int | History of piperidinylpyridinylcarbonitrile as inhibitors of glutaminyl-peptide cyclotransferase and glutaminyl-peptide cyclotransferase-like protein |
| CN117538462B (zh) * | 2024-01-10 | 2024-03-26 | 地奥集团成都药业股份有限公司 | 一种氨氯地平贝那普利胶囊有关物质的检测方法 |
| WO2025240620A1 (en) * | 2024-05-14 | 2025-11-20 | Pronovo Therapeutics Inc. | Selective dual agonists of muscarinic 1 and 4 receptors and therapeutic uses thereof |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0640599T3 (da) * | 1993-08-26 | 1998-09-28 | Ono Pharmaceutical Co | 4-Aminopyrimidin-derivater |
| US6262059B1 (en) | 1995-06-07 | 2001-07-17 | Cell Pathways, Inc. | Method of treating a patient having precancerous lesions with quinazoline derivatives |
| US7064215B2 (en) * | 2001-07-03 | 2006-06-20 | Chiron Corporation | Indazole benzimidazole compounds |
| US7642278B2 (en) * | 2001-07-03 | 2010-01-05 | Novartis Vaccines And Diagnostics, Inc. | Indazole benzimidazole compounds |
| US8673924B2 (en) * | 2002-09-04 | 2014-03-18 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
| WO2005004818A2 (en) * | 2003-07-09 | 2005-01-20 | Imclone Systems Incorporated | Heterocyclic compounds and their use as anticancer agents |
| EP1781659B1 (en) * | 2003-07-16 | 2008-11-05 | Janssen Pharmaceutica N.V. | Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors |
| AU2005205201B2 (en) * | 2004-01-12 | 2011-05-12 | Merck Serono Sa | Thiazole derivatives and use thereof |
| EP1718306A2 (en) * | 2004-02-20 | 2006-11-08 | Chiron Corporation | Modulation of inflammatory and metastatic processes |
| MX2007000631A (es) * | 2004-07-16 | 2007-03-30 | Sunesis Pharmaceuticals Inc | Tienopirimidinas utiles como inhibidores de aurora cinasa. |
| JP2008508358A (ja) * | 2004-08-02 | 2008-03-21 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | アリール−アミノ置換ピロロピリミジンマルチキナーゼ阻害化合物 |
| GB0520958D0 (en) * | 2005-10-14 | 2005-11-23 | Cyclacel Ltd | Compound |
| WO2007067537A1 (en) * | 2005-12-07 | 2007-06-14 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine kinase inhibiting compounds |
| JO2660B1 (en) * | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| AR060358A1 (es) * | 2006-04-06 | 2008-06-11 | Novartis Vaccines & Diagnostic | Quinazolinas para la inhibicion de pdk 1 |
| US7893058B2 (en) * | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| CN101511800B (zh) * | 2006-07-14 | 2013-02-27 | 坎莫森特里克斯公司 | 三唑基苯基苯磺酰胺 |
| JP2010514693A (ja) * | 2006-12-22 | 2010-05-06 | ノバルティス アーゲー | Ｐｄｋ１阻害のためのキナゾリン |
| CN101568529A (zh) * | 2006-12-22 | 2009-10-28 | 诺瓦提斯公司 | 作为cdk抑制剂、用于治疗癌症、炎症和病毒感染的杂芳基-杂芳基化合物 |
| WO2008128986A1 (en) * | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Urea derivatives as glutaminyl cyclase inhibitors |
| WO2008128984A1 (en) * | 2007-04-20 | 2008-10-30 | Probiodrug Ag | Aminopyrimidine derivatives as glutaminyl cyclase inhibitors |
| JP5611826B2 (ja) * | 2007-09-04 | 2014-10-22 | ザ スクリプス リサーチ インスティテュート | タンパク質キナーゼ阻害剤としての置換されたピリミジニル−アミン |
| EP2326627A1 (en) * | 2008-08-20 | 2011-06-01 | Schering Corporation | Substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
| CN102186475B (zh) * | 2008-09-04 | 2016-08-03 | 前体生物药物股份公司 | 新抑制剂 |
| JP5934645B2 (ja) * | 2009-09-11 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体 |
| JP6026284B2 (ja) * | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| NZ602312A (en) * | 2010-03-10 | 2014-02-28 | Probiodrug Ag | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
| WO2011131748A2 (en) * | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| JP2014500254A (ja) * | 2010-11-09 | 2014-01-09 | セルゾーム リミティッド | Ｔｙｋ２阻害剤としてのピリジン化合物およびそのアザ類似体 |
| NO2638031T3 (https=) * | 2010-11-10 | 2018-03-10 | ||
| US8785459B2 (en) | 2011-12-27 | 2014-07-22 | Development Center For Biotechnology | Quinazoline compounds as kinase inhibitors |
| EP2844652B1 (en) * | 2012-05-03 | 2019-03-13 | Genentech, Inc. | Pyrazole aminopyrimidine derivatives as lrrk2 modulators |
| WO2014081718A1 (en) * | 2012-11-20 | 2014-05-30 | Genentech, Inc. | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants |
| MX367855B (es) * | 2013-03-15 | 2019-09-09 | Probiodrug Ag | Inhibidores novedosos. |
| MA40957A (fr) * | 2014-10-09 | 2017-09-19 | Biomarin Pharm Inc | Inhibiteurs de biosynthèse d'héparane sulfate pour traiter des maladies |
| CA2979302A1 (en) * | 2015-05-13 | 2016-11-17 | Selvita S.A. | Substituted quinoxaline derivatives |
| EP3334733A1 (en) * | 2015-08-10 | 2018-06-20 | Pfizer Inc | 3-indol substituted derivatives, pharmaceutical compositions and methods for use |
| SG11201804901WA (en) * | 2015-12-22 | 2018-07-30 | SHY Therapeutics LLC | Compounds for the treatment of cancer and inflammatory disease |
| US10034861B2 (en) * | 2016-07-04 | 2018-07-31 | H. Lundbeck A/S | 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors |
-
2017
- 2017-03-31 GB GBGB1705263.0A patent/GB201705263D0/en not_active Ceased
-
2018
- 2018-04-03 CA CA3221839A patent/CA3221839A1/en active Pending
- 2018-04-03 IL IL297534A patent/IL297534A/en unknown
- 2018-04-03 CN CN201880035826.8A patent/CN110719910B/zh active Active
- 2018-04-03 IL IL269196A patent/IL269196B2/en unknown
- 2018-04-03 EP EP18718725.7A patent/EP3601269A1/en active Pending
- 2018-04-03 US US16/497,040 patent/US11339152B2/en active Active
- 2018-04-03 AU AU2018246382A patent/AU2018246382C1/en active Active
- 2018-04-03 CA CA3057783A patent/CA3057783A1/en active Pending
- 2018-04-03 WO PCT/EP2018/058391 patent/WO2018178384A1/en not_active Ceased
- 2018-04-03 KR KR1020247039667A patent/KR20250002689A/ko active Pending
- 2018-04-03 MX MX2019011544A patent/MX2019011544A/es unknown
- 2018-04-03 KR KR1020197028930A patent/KR102737532B1/ko active Active
- 2018-04-03 JP JP2019553478A patent/JP7674811B2/ja active Active
- 2018-04-03 CN CN202310828597.8A patent/CN117024352A/zh active Pending
- 2018-04-03 EA EA201992120A patent/EA201992120A1/ru unknown
-
2019
- 2019-09-03 ZA ZA2019/05811A patent/ZA201905811B/en unknown
- 2019-09-26 MX MX2022007317A patent/MX2022007317A/es unknown
-
2022
- 2022-05-05 US US17/737,602 patent/US12384772B2/en active Active
- 2022-05-20 JP JP2022082769A patent/JP7589191B2/ja active Active
- 2022-10-05 AU AU2022246405A patent/AU2022246405B2/en active Active
-
2023
- 2023-10-22 IL IL307911A patent/IL307911B1/en unknown
-
2024
- 2024-07-03 JP JP2024107135A patent/JP2024153639A/ja active Pending
-
2025
- 2025-07-07 US US19/261,178 patent/US20260001873A1/en active Pending
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