JP2020511473A5 - - Google Patents

Download PDF

Info

Publication number
JP2020511473A5
JP2020511473A5 JP2019551284A JP2019551284A JP2020511473A5 JP 2020511473 A5 JP2020511473 A5 JP 2020511473A5 JP 2019551284 A JP2019551284 A JP 2019551284A JP 2019551284 A JP2019551284 A JP 2019551284A JP 2020511473 A5 JP2020511473 A5 JP 2020511473A5
Authority
JP
Japan
Prior art keywords
epilepsy
composition according
seizures
syndrome
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019551284A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020511473A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/022573 external-priority patent/WO2018170223A1/en
Publication of JP2020511473A publication Critical patent/JP2020511473A/ja
Publication of JP2020511473A5 publication Critical patent/JP2020511473A5/ja
Pending legal-status Critical Current

Links

JP2019551284A 2017-03-15 2018-03-15 発作性疾患の治療におけるデザイナー化合物によりのみ活性化するデザイナー受容体の使用 Pending JP2020511473A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762471635P 2017-03-15 2017-03-15
US62/471,635 2017-03-15
US201762608207P 2017-12-20 2017-12-20
US62/608,207 2017-12-20
US201862635871P 2018-02-27 2018-02-27
US62/635,871 2018-02-27
PCT/US2018/022573 WO2018170223A1 (en) 2017-03-15 2018-03-15 Use of designer receptors exclusively activated by designer drugs in the treatment of seizure disorders

Publications (2)

Publication Number Publication Date
JP2020511473A JP2020511473A (ja) 2020-04-16
JP2020511473A5 true JP2020511473A5 (https=) 2021-04-22

Family

ID=63523332

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019551284A Pending JP2020511473A (ja) 2017-03-15 2018-03-15 発作性疾患の治療におけるデザイナー化合物によりのみ活性化するデザイナー受容体の使用

Country Status (11)

Country Link
US (1) US20190060400A1 (https=)
EP (1) EP3595669A4 (https=)
JP (1) JP2020511473A (https=)
KR (1) KR20190124309A (https=)
CN (1) CN110621318A (https=)
AU (1) AU2018234644A1 (https=)
BR (1) BR112019019078A2 (https=)
CA (1) CA3056410A1 (https=)
IL (1) IL269310A (https=)
MX (1) MX2019010982A (https=)
WO (1) WO2018170223A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020002148A (es) * 2017-08-25 2020-07-20 Ovid Therapeutics Inc Vectores adenoasociados recombinantes.
CA3084985A1 (en) 2017-12-06 2019-06-13 Ovid Therapeutics Inc. Use of mir101 or mir128 in the treatment of seizure disorders
WO2019113538A2 (en) * 2017-12-07 2019-06-13 California Institute Of Technology Methods and systems for noninvasive control of brain cells and related vectors and compositions
CN111867595A (zh) * 2017-12-20 2020-10-30 奥维德医疗公司 hM4Di在治疗癫痫发作紊乱中的用途
US11123332B2 (en) 2018-11-21 2021-09-21 Certego Therapeutics Inc. Gaboxadol for reducing risk of suicide and rapid relief of depression
MX2022009982A (es) * 2020-02-14 2022-09-12 Ultragenyx Pharmaceutical Inc Terapia genica para el tratamiento de transtorno por deficiencia de cdkl5.
MX2022014599A (es) 2020-05-20 2022-12-16 Certego Therapeutics Inc Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos.
KR102878106B1 (ko) * 2021-12-24 2025-10-28 서울대학교산학협력단 신경수초 가소성 증진 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003221733A1 (en) * 2002-04-17 2003-11-03 University Of Florida Research Foundation, Inc. Improved raav vectors
GB201404470D0 (en) * 2014-03-13 2014-04-30 Ucl Business Plc Therapeutic methods and materials

Similar Documents

Publication Publication Date Title
JP2020511473A5 (https=)
US20230263910A1 (en) Aav vectors targeted to the central nervous system
US12076351B2 (en) AAV vectors targeted to oligodendrocytes
JP2019089787A5 (https=)
CN106488984B (zh) 一种治疗周围神经病变以及运动神经元疾病的方法
IL273261B1 (en) Adeno-associated virus variant capsids and methods of use thereof
JP2017533715A5 (https=)
Reid et al. miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity
JP2019519218A5 (https=)
JP2019513393A5 (https=)
CN107893078B (zh) 靶向突触结合蛋白-11的siRNA、表达载体和病毒颗粒及其制药应用
TW201629225A (zh) 第九因子基因療法
US20220380807A1 (en) Method for reducing the expression of nkcc1 in a subject
JP2017506230A5 (https=)
EP4045653A1 (en) Gene therapy for alzheimer's disease
JP2021505619A5 (https=)
CN112029773B (zh) 编码bdnf的核酸及其应用
US20230313223A1 (en) Methods for modulating level of expression from gene therapy expression cassette
CN114126667A (zh) 使用糖苷水解酶的基因疗法载体向视网膜细胞的改进递送
JP2018509912A5 (https=)
EP4689120A2 (en) Compositions and methods for treating cag repeat diseases
Cagin Targeting age-related neurodegenerative diseases by AAV-Mediated gene therapy
Arora et al. Gene therapies for neurodegenerative disease: current knowledge and challenges
WO2022226294A1 (en) Chimeric aav5 capsids
WO2025164317A1 (ja) 改良型ミクログリア標的aavベクター