KR20190124309A - 발작 장애들의 치료에 있어 디자이너 약물들에 의하여 배타적으로 활성화되는 디자이너 수용체들의 용도 - Google Patents

발작 장애들의 치료에 있어 디자이너 약물들에 의하여 배타적으로 활성화되는 디자이너 수용체들의 용도 Download PDF

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KR20190124309A
KR20190124309A KR1020197030149A KR20197030149A KR20190124309A KR 20190124309 A KR20190124309 A KR 20190124309A KR 1020197030149 A KR1020197030149 A KR 1020197030149A KR 20197030149 A KR20197030149 A KR 20197030149A KR 20190124309 A KR20190124309 A KR 20190124309A
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seizures
epilepsy
day
patient
vector
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매튜 듀링
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오비드 테라퓨틱스 인크.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1787Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0085Brain, e.g. brain implants; Spinal cord
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
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    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2820/00Vectors comprising a special origin of replication system
    • C12N2820/10Vectors comprising a special origin of replication system multiple origins of replication
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/50Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
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  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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KR1020197030149A 2017-03-15 2018-03-15 발작 장애들의 치료에 있어 디자이너 약물들에 의하여 배타적으로 활성화되는 디자이너 수용체들의 용도 Withdrawn KR20190124309A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762471635P 2017-03-15 2017-03-15
US62/471,635 2017-03-15
US201762608207P 2017-12-20 2017-12-20
US62/608,207 2017-12-20
US201862635871P 2018-02-27 2018-02-27
US62/635,871 2018-02-27
PCT/US2018/022573 WO2018170223A1 (en) 2017-03-15 2018-03-15 Use of designer receptors exclusively activated by designer drugs in the treatment of seizure disorders

Publications (1)

Publication Number Publication Date
KR20190124309A true KR20190124309A (ko) 2019-11-04

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KR1020197030149A Withdrawn KR20190124309A (ko) 2017-03-15 2018-03-15 발작 장애들의 치료에 있어 디자이너 약물들에 의하여 배타적으로 활성화되는 디자이너 수용체들의 용도

Country Status (11)

Country Link
US (1) US20190060400A1 (https=)
EP (1) EP3595669A4 (https=)
JP (1) JP2020511473A (https=)
KR (1) KR20190124309A (https=)
CN (1) CN110621318A (https=)
AU (1) AU2018234644A1 (https=)
BR (1) BR112019019078A2 (https=)
CA (1) CA3056410A1 (https=)
IL (1) IL269310A (https=)
MX (1) MX2019010982A (https=)
WO (1) WO2018170223A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230097463A (ko) * 2021-12-24 2023-07-03 서울대학교산학협력단 신경수초 가소성 증진 방법

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020002148A (es) * 2017-08-25 2020-07-20 Ovid Therapeutics Inc Vectores adenoasociados recombinantes.
CA3084985A1 (en) 2017-12-06 2019-06-13 Ovid Therapeutics Inc. Use of mir101 or mir128 in the treatment of seizure disorders
WO2019113538A2 (en) * 2017-12-07 2019-06-13 California Institute Of Technology Methods and systems for noninvasive control of brain cells and related vectors and compositions
CN111867595A (zh) * 2017-12-20 2020-10-30 奥维德医疗公司 hM4Di在治疗癫痫发作紊乱中的用途
US11123332B2 (en) 2018-11-21 2021-09-21 Certego Therapeutics Inc. Gaboxadol for reducing risk of suicide and rapid relief of depression
MX2022009982A (es) * 2020-02-14 2022-09-12 Ultragenyx Pharmaceutical Inc Terapia genica para el tratamiento de transtorno por deficiencia de cdkl5.
MX2022014599A (es) 2020-05-20 2022-12-16 Certego Therapeutics Inc Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003221733A1 (en) * 2002-04-17 2003-11-03 University Of Florida Research Foundation, Inc. Improved raav vectors
GB201404470D0 (en) * 2014-03-13 2014-04-30 Ucl Business Plc Therapeutic methods and materials

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230097463A (ko) * 2021-12-24 2023-07-03 서울대학교산학협력단 신경수초 가소성 증진 방법

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Publication number Publication date
EP3595669A4 (en) 2021-03-03
WO2018170223A1 (en) 2018-09-20
US20190060400A1 (en) 2019-02-28
BR112019019078A2 (pt) 2020-04-22
EP3595669A1 (en) 2020-01-22
IL269310A (en) 2019-11-28
AU2018234644A1 (en) 2019-10-03
CA3056410A1 (en) 2018-09-20
JP2020511473A (ja) 2020-04-16
CN110621318A (zh) 2019-12-27
MX2019010982A (es) 2020-02-10

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