JP2021505619A5 - - Google Patents

Download PDF

Info

Publication number
JP2021505619A5
JP2021505619A5 JP2020531161A JP2020531161A JP2021505619A5 JP 2021505619 A5 JP2021505619 A5 JP 2021505619A5 JP 2020531161 A JP2020531161 A JP 2020531161A JP 2020531161 A JP2020531161 A JP 2020531161A JP 2021505619 A5 JP2021505619 A5 JP 2021505619A5
Authority
JP
Japan
Prior art keywords
epilepsy
composition according
premir101
vector
microrna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020531161A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021505619A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/064158 external-priority patent/WO2019113266A1/en
Publication of JP2021505619A publication Critical patent/JP2021505619A/ja
Publication of JP2021505619A5 publication Critical patent/JP2021505619A5/ja
Pending legal-status Critical Current

Links

JP2020531161A 2017-12-06 2018-12-06 発作障害の治療におけるmir101またはmir128の使用 Pending JP2021505619A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762595255P 2017-12-06 2017-12-06
US62/595,255 2017-12-06
PCT/US2018/064158 WO2019113266A1 (en) 2017-12-06 2018-12-06 Use of mir101 or mir128 in the treatment of seizure disorders

Publications (2)

Publication Number Publication Date
JP2021505619A JP2021505619A (ja) 2021-02-18
JP2021505619A5 true JP2021505619A5 (https=) 2022-01-11

Family

ID=66658874

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020531161A Pending JP2021505619A (ja) 2017-12-06 2018-12-06 発作障害の治療におけるmir101またはmir128の使用

Country Status (10)

Country Link
US (2) US10870855B2 (https=)
EP (1) EP3703820A4 (https=)
JP (1) JP2021505619A (https=)
KR (1) KR20200119782A (https=)
CN (1) CN111417397A (https=)
AU (1) AU2018378622A1 (https=)
CA (1) CA3084985A1 (https=)
IL (1) IL274838A (https=)
MX (2) MX388998B (https=)
WO (1) WO2019113266A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3084985A1 (en) 2017-12-06 2019-06-13 Ovid Therapeutics Inc. Use of mir101 or mir128 in the treatment of seizure disorders
BR112022002794A2 (pt) * 2019-08-15 2022-08-09 Childrens Hospital Philadelphia Terapia combinada de transgene e mirna derivado de íntron para tratamento de sca1
WO2025164317A1 (ja) * 2024-01-31 2025-08-07 国立大学法人群馬大学 改良型ミクログリア標的aavベクター

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499437A (en) 1967-03-10 1970-03-10 Ultrasonic Systems Method and apparatus for treatment of organic structures and systems thereof with ultrasonic energy
US4303636A (en) 1974-08-20 1981-12-01 Gordon Robert T Cancer treatment
US4315514A (en) 1980-05-08 1982-02-16 William Drewes Method and apparatus for selective cell destruction
US4923437A (en) 1986-07-18 1990-05-08 Gordon Robert T Process for applying a localized magnetic or electric field
US5059415A (en) 1989-02-21 1991-10-22 The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon Health Method for diagnostically imaging lesions in the brain inside a blood-brain barrier
US5112596A (en) 1990-04-23 1992-05-12 Alkermes, Inc. Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
US5438989A (en) 1990-08-10 1995-08-08 Hochman; Darryl Solid tumor, cortical function, and nerve tissue imaging methods and device
US5465718A (en) 1990-08-10 1995-11-14 Hochman; Daryl Solid tumor, cortical function, and nerve tissue imaging methods and device
DE4227800C2 (de) 1991-08-21 1996-12-19 Toshiba Kawasaki Kk Thrombuslösende Behandlungsvorrichtung
US5291890A (en) 1991-08-29 1994-03-08 General Electric Company Magnetic resonance surgery using heat waves produced with focussed ultrasound
US5524620A (en) 1991-11-12 1996-06-11 November Technologies Ltd. Ablation of blood thrombi by means of acoustic energy
JP3325300B2 (ja) 1992-02-28 2002-09-17 株式会社東芝 超音波治療装置
US5368032A (en) 1993-11-09 1994-11-29 General Electric Company Manually positioned focussed energy system guided by medical imaging
US5526814A (en) 1993-11-09 1996-06-18 General Electric Company Automatically positioned focussed energy system guided by medical imaging
US5443068A (en) 1994-09-26 1995-08-22 General Electric Company Mechanical positioner for magnetic resonance guided ultrasound therapy
US5752515A (en) 1996-08-21 1998-05-19 Brigham & Women's Hospital Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier
EP1937151A4 (en) 2005-09-19 2011-07-06 Univ Columbia Systems and methods for opening of the blood-brain barrier of a subject using ultrasound
EP2068925A4 (en) * 2007-05-07 2011-08-31 Medimmune Llc ANTI-ICOS ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER, TRANSPLANTATIONS AND AUTOIMMUNE DISEASES
US9163261B2 (en) * 2010-02-22 2015-10-20 Koteswara Rao KOLLIPARA Adeno-associated virus 2/8—micro RNA-101 therapy for liver cancer
GB201103062D0 (en) * 2011-02-22 2011-04-06 Isis Innovation Method
GB201223244D0 (en) * 2012-12-21 2013-02-06 Ucb Pharma Gmbh Micrornas as therapeutics and biomarkers for epilepsy
CN107207597A (zh) * 2014-11-06 2017-09-26 儿研所儿童医学中心 用于癌症和自身免疫疾病的免疫疗法
TN2017000354A1 (en) * 2015-02-10 2019-01-16 Genzyme Corp VARIANT RNAi
WO2017024111A1 (en) * 2015-08-04 2017-02-09 The University Of Chicago Inhibitors of cacna1a/alpha1a subunit internal ribosomal entry site (ires) and methods of treating spinocerebellar ataxia type 6
EP3413925A1 (en) * 2016-02-12 2018-12-19 Combigene AB Vector
CA3056410A1 (en) * 2017-03-15 2018-09-20 Ovid Therapeutics, Inc. Use of designer receptors exclusively activated by designer drugs in the treatment of seizure disorders
CA3084985A1 (en) 2017-12-06 2019-06-13 Ovid Therapeutics Inc. Use of mir101 or mir128 in the treatment of seizure disorders

Similar Documents

Publication Publication Date Title
US20220331409A1 (en) Factor ix gene therapy
JP2021106619A5 (https=)
JP2020511473A5 (https=)
JP2021505619A5 (https=)
JP2025179046A5 (https=)
JP2020527333A5 (https=)
JP2024095717A5 (https=)
KR102380265B1 (ko) 변종 aav 및 조성물, 세포, 기관 및 조직으로의 유전자 전이를 위한 방법 및 용도
RU2020109343A (ru) Полинуклеотиды aadc для лечения болезни паркинсона
JP2021502060A5 (https=)
JP2018148927A5 (https=)
JP2020522269A5 (https=)
JP2022500066A5 (https=)
JP2021500049A (ja) 神経変性疾患の遺伝子治療
RU2018129159A (ru) Рекомбинантные aav векторы, экспрессирующие остеопротективные гены, включая has2 и лубрицин, пригодные при лечении остеоартрита и сходных заболеваний суставов у млекопитающих
US20220380807A1 (en) Method for reducing the expression of nkcc1 in a subject
JP2021527087A5 (https=)
US20220378945A1 (en) Gene therapy targeting cochlear cells
JPWO2020069461A5 (https=)
JP2022527597A (ja) 筋肉発現のためのハイブリッドプロモーター
JP2021510301A5 (https=)
AU2020367437B2 (en) Gene therapy for Alzheimer's disease
JP2021531044A5 (https=)
CN112029773B (zh) 编码bdnf的核酸及其应用
WO2021231575A1 (en) Immunosuppressive agents and viral delivery re-dosing methods for gene therapy