JP2021505619A5 - - Google Patents
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- Publication number
- JP2021505619A5 JP2021505619A5 JP2020531161A JP2020531161A JP2021505619A5 JP 2021505619 A5 JP2021505619 A5 JP 2021505619A5 JP 2020531161 A JP2020531161 A JP 2020531161A JP 2020531161 A JP2020531161 A JP 2020531161A JP 2021505619 A5 JP2021505619 A5 JP 2021505619A5
- Authority
- JP
- Japan
- Prior art keywords
- epilepsy
- composition according
- premir101
- vector
- microrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762595255P | 2017-12-06 | 2017-12-06 | |
| US62/595,255 | 2017-12-06 | ||
| PCT/US2018/064158 WO2019113266A1 (en) | 2017-12-06 | 2018-12-06 | Use of mir101 or mir128 in the treatment of seizure disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021505619A JP2021505619A (ja) | 2021-02-18 |
| JP2021505619A5 true JP2021505619A5 (https=) | 2022-01-11 |
Family
ID=66658874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531161A Pending JP2021505619A (ja) | 2017-12-06 | 2018-12-06 | 発作障害の治療におけるmir101またはmir128の使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10870855B2 (https=) |
| EP (1) | EP3703820A4 (https=) |
| JP (1) | JP2021505619A (https=) |
| KR (1) | KR20200119782A (https=) |
| CN (1) | CN111417397A (https=) |
| AU (1) | AU2018378622A1 (https=) |
| CA (1) | CA3084985A1 (https=) |
| IL (1) | IL274838A (https=) |
| MX (2) | MX388998B (https=) |
| WO (1) | WO2019113266A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3084985A1 (en) | 2017-12-06 | 2019-06-13 | Ovid Therapeutics Inc. | Use of mir101 or mir128 in the treatment of seizure disorders |
| BR112022002794A2 (pt) * | 2019-08-15 | 2022-08-09 | Childrens Hospital Philadelphia | Terapia combinada de transgene e mirna derivado de íntron para tratamento de sca1 |
| WO2025164317A1 (ja) * | 2024-01-31 | 2025-08-07 | 国立大学法人群馬大学 | 改良型ミクログリア標的aavベクター |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3499437A (en) | 1967-03-10 | 1970-03-10 | Ultrasonic Systems | Method and apparatus for treatment of organic structures and systems thereof with ultrasonic energy |
| US4303636A (en) | 1974-08-20 | 1981-12-01 | Gordon Robert T | Cancer treatment |
| US4315514A (en) | 1980-05-08 | 1982-02-16 | William Drewes | Method and apparatus for selective cell destruction |
| US4923437A (en) | 1986-07-18 | 1990-05-08 | Gordon Robert T | Process for applying a localized magnetic or electric field |
| US5059415A (en) | 1989-02-21 | 1991-10-22 | The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon Health | Method for diagnostically imaging lesions in the brain inside a blood-brain barrier |
| US5112596A (en) | 1990-04-23 | 1992-05-12 | Alkermes, Inc. | Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability |
| US5438989A (en) | 1990-08-10 | 1995-08-08 | Hochman; Darryl | Solid tumor, cortical function, and nerve tissue imaging methods and device |
| US5465718A (en) | 1990-08-10 | 1995-11-14 | Hochman; Daryl | Solid tumor, cortical function, and nerve tissue imaging methods and device |
| DE4227800C2 (de) | 1991-08-21 | 1996-12-19 | Toshiba Kawasaki Kk | Thrombuslösende Behandlungsvorrichtung |
| US5291890A (en) | 1991-08-29 | 1994-03-08 | General Electric Company | Magnetic resonance surgery using heat waves produced with focussed ultrasound |
| US5524620A (en) | 1991-11-12 | 1996-06-11 | November Technologies Ltd. | Ablation of blood thrombi by means of acoustic energy |
| JP3325300B2 (ja) | 1992-02-28 | 2002-09-17 | 株式会社東芝 | 超音波治療装置 |
| US5368032A (en) | 1993-11-09 | 1994-11-29 | General Electric Company | Manually positioned focussed energy system guided by medical imaging |
| US5526814A (en) | 1993-11-09 | 1996-06-18 | General Electric Company | Automatically positioned focussed energy system guided by medical imaging |
| US5443068A (en) | 1994-09-26 | 1995-08-22 | General Electric Company | Mechanical positioner for magnetic resonance guided ultrasound therapy |
| US5752515A (en) | 1996-08-21 | 1998-05-19 | Brigham & Women's Hospital | Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier |
| EP1937151A4 (en) | 2005-09-19 | 2011-07-06 | Univ Columbia | Systems and methods for opening of the blood-brain barrier of a subject using ultrasound |
| EP2068925A4 (en) * | 2007-05-07 | 2011-08-31 | Medimmune Llc | ANTI-ICOS ANTIBODIES AND THEIR USE FOR THE TREATMENT OF CANCER, TRANSPLANTATIONS AND AUTOIMMUNE DISEASES |
| US9163261B2 (en) * | 2010-02-22 | 2015-10-20 | Koteswara Rao KOLLIPARA | Adeno-associated virus 2/8—micro RNA-101 therapy for liver cancer |
| GB201103062D0 (en) * | 2011-02-22 | 2011-04-06 | Isis Innovation | Method |
| GB201223244D0 (en) * | 2012-12-21 | 2013-02-06 | Ucb Pharma Gmbh | Micrornas as therapeutics and biomarkers for epilepsy |
| CN107207597A (zh) * | 2014-11-06 | 2017-09-26 | 儿研所儿童医学中心 | 用于癌症和自身免疫疾病的免疫疗法 |
| TN2017000354A1 (en) * | 2015-02-10 | 2019-01-16 | Genzyme Corp | VARIANT RNAi |
| WO2017024111A1 (en) * | 2015-08-04 | 2017-02-09 | The University Of Chicago | Inhibitors of cacna1a/alpha1a subunit internal ribosomal entry site (ires) and methods of treating spinocerebellar ataxia type 6 |
| EP3413925A1 (en) * | 2016-02-12 | 2018-12-19 | Combigene AB | Vector |
| CA3056410A1 (en) * | 2017-03-15 | 2018-09-20 | Ovid Therapeutics, Inc. | Use of designer receptors exclusively activated by designer drugs in the treatment of seizure disorders |
| CA3084985A1 (en) | 2017-12-06 | 2019-06-13 | Ovid Therapeutics Inc. | Use of mir101 or mir128 in the treatment of seizure disorders |
-
2018
- 2018-12-06 CA CA3084985A patent/CA3084985A1/en active Pending
- 2018-12-06 WO PCT/US2018/064158 patent/WO2019113266A1/en not_active Ceased
- 2018-12-06 US US16/211,309 patent/US10870855B2/en active Active
- 2018-12-06 JP JP2020531161A patent/JP2021505619A/ja active Pending
- 2018-12-06 KR KR1020207019430A patent/KR20200119782A/ko not_active Withdrawn
- 2018-12-06 EP EP18886725.3A patent/EP3703820A4/en not_active Withdrawn
- 2018-12-06 AU AU2018378622A patent/AU2018378622A1/en not_active Abandoned
- 2018-12-06 MX MX2020005952A patent/MX388998B/es unknown
- 2018-12-06 CN CN201880076488.2A patent/CN111417397A/zh active Pending
-
2020
- 2020-05-21 IL IL274838A patent/IL274838A/en unknown
- 2020-07-13 MX MX2021011598A patent/MX2021011598A/es unknown
- 2020-11-17 US US16/950,395 patent/US11761006B2/en active Active
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