JP2020510014A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020510014A5 JP2020510014A5 JP2019548431A JP2019548431A JP2020510014A5 JP 2020510014 A5 JP2020510014 A5 JP 2020510014A5 JP 2019548431 A JP2019548431 A JP 2019548431A JP 2019548431 A JP2019548431 A JP 2019548431A JP 2020510014 A5 JP2020510014 A5 JP 2020510014A5
- Authority
- JP
- Japan
- Prior art keywords
- dialysate
- spiked
- pharmaceutical composition
- nitrite
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 claims description 104
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 claims description 94
- 229940005654 nitrite ion Drugs 0.000 claims description 91
- 238000000502 dialysis Methods 0.000 claims description 57
- 235000010288 sodium nitrite Nutrition 0.000 claims description 52
- 239000007864 aqueous solution Substances 0.000 claims description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 18
- 239000012141 concentrate Substances 0.000 claims description 16
- 239000012528 membrane Substances 0.000 claims description 13
- 239000002253 acid Substances 0.000 claims description 12
- 210000004369 blood Anatomy 0.000 claims description 12
- 239000008280 blood Substances 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 11
- 239000000243 solution Substances 0.000 claims description 11
- -1 nitrite ions Chemical class 0.000 claims description 9
- 208000009304 Acute Kidney Injury Diseases 0.000 claims description 7
- 208000033626 Renal failure acute Diseases 0.000 claims description 7
- 201000011040 acute kidney failure Diseases 0.000 claims description 7
- 208000012998 acute renal failure Diseases 0.000 claims description 7
- 208000020832 chronic kidney disease Diseases 0.000 claims description 7
- 208000022831 chronic renal failure syndrome Diseases 0.000 claims description 7
- 206010002383 Angina Pectoris Diseases 0.000 claims description 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims description 2
- 206010059109 Cerebral vasoconstriction Diseases 0.000 claims description 2
- 206010020772 Hypertension Diseases 0.000 claims description 2
- 208000018262 Peripheral vascular disease Diseases 0.000 claims description 2
- 208000001286 intracranial vasospasm Diseases 0.000 claims description 2
- 208000028867 ischemia Diseases 0.000 claims description 2
- 230000000302 ischemic effect Effects 0.000 claims description 2
- 208000030175 lameness Diseases 0.000 claims description 2
- 208000010125 myocardial infarction Diseases 0.000 claims description 2
- 208000002815 pulmonary hypertension Diseases 0.000 claims description 2
- 206010038464 renal hypertension Diseases 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 35
- 230000002265 prevention Effects 0.000 claims 5
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
- 206010049993 Cardiac death Diseases 0.000 claims 1
- 206010011906 Death Diseases 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 238000001631 haemodialysis Methods 0.000 claims 1
- 230000000322 hemodialysis Effects 0.000 claims 1
- 150000002826 nitrites Chemical class 0.000 claims 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 description 120
- 206010049418 Sudden Cardiac Death Diseases 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 230000000925 erythroid effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023114331A JP7551858B2 (ja) | 2017-03-08 | 2023-07-12 | 亜硝酸ナトリウムの透析中の使用 |
| JP2024152352A JP7765687B2 (ja) | 2017-03-08 | 2024-09-04 | 亜硝酸ナトリウムの透析中の使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762468857P | 2017-03-08 | 2017-03-08 | |
| US62/468,857 | 2017-03-08 | ||
| PCT/US2018/021053 WO2018165098A1 (en) | 2017-03-08 | 2018-03-06 | Intradialytic use of sodium nitrite |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114331A Division JP7551858B2 (ja) | 2017-03-08 | 2023-07-12 | 亜硝酸ナトリウムの透析中の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510014A JP2020510014A (ja) | 2020-04-02 |
| JP2020510014A5 true JP2020510014A5 (https=) | 2021-04-22 |
| JP7314050B2 JP7314050B2 (ja) | 2023-07-25 |
Family
ID=63445965
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548431A Active JP7314050B2 (ja) | 2017-03-08 | 2018-03-06 | 亜硝酸ナトリウムの透析中の使用 |
| JP2023114331A Active JP7551858B2 (ja) | 2017-03-08 | 2023-07-12 | 亜硝酸ナトリウムの透析中の使用 |
| JP2024152352A Active JP7765687B2 (ja) | 2017-03-08 | 2024-09-04 | 亜硝酸ナトリウムの透析中の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023114331A Active JP7551858B2 (ja) | 2017-03-08 | 2023-07-12 | 亜硝酸ナトリウムの透析中の使用 |
| JP2024152352A Active JP7765687B2 (ja) | 2017-03-08 | 2024-09-04 | 亜硝酸ナトリウムの透析中の使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US10328099B2 (https=) |
| EP (2) | EP4406595A3 (https=) |
| JP (3) | JP7314050B2 (https=) |
| KR (4) | KR20250017763A (https=) |
| AR (1) | AR111166A1 (https=) |
| AU (2) | AU2018231016B2 (https=) |
| BR (1) | BR112019018861A2 (https=) |
| CA (1) | CA3055105A1 (https=) |
| ES (1) | ES2986444T3 (https=) |
| IL (4) | IL312092B2 (https=) |
| NZ (4) | NZ797744A (https=) |
| PH (1) | PH12019501950A1 (https=) |
| TW (3) | TWI835595B (https=) |
| WO (1) | WO2018165098A1 (https=) |
| ZA (3) | ZA201905679B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019018861A2 (pt) * | 2017-03-08 | 2023-10-10 | Hope Medical Entpr Inc Dba Hope Pharmaceuticals | Uso de nitrito de sódio, método para manter os níveis fisiológicos de nitrito, prevenir enfarte do miocárdio, prevenir morte súbita cardíaca, prevenir acidente vascular cerebral, doenças cardiovasculares, pressão alta, solução aquosa |
| IL268883B (en) | 2017-03-08 | 2022-09-01 | Hope Medical Entpr Inc Dba Hope Pharmaceuticals | Intradialytic use of sodium thiosulfate |
| EP4005611B1 (en) * | 2019-07-22 | 2025-11-26 | School Juridical Person The Kitasato Institute | Dialysis device |
| US20230149732A1 (en) * | 2021-11-17 | 2023-05-18 | Wake Forest University Health Sciences | Combined nitrite and light treatment to prevent device thrombosis |
| CN120456938A (zh) | 2022-12-16 | 2025-08-08 | 费森尤斯医疗保健控股公司 | 用于在透析中使用一氧化氮的系统和方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0218900B1 (en) | 1985-09-10 | 1992-01-22 | Research Corporation Technologies, Inc. | Osmotic agents for peritoneal dialysis |
| US6380163B1 (en) | 1992-12-22 | 2002-04-30 | Baxter International Inc. | Peritoneal dialysis solutions with polypeptides |
| FI98538C (fi) | 1993-10-20 | 1997-07-10 | Enso Gutzeit Oy | Menetelmä natriumhydroksidin valmistamiseksi valkolipeästä |
| US6306836B1 (en) | 1994-01-21 | 2001-10-23 | Baxter International Inc. | Peritoneal dialysis solutions containing maltodextrins and amino acids |
| US6436969B1 (en) | 1995-09-12 | 2002-08-20 | Kansas University Medical Center Research Institute Inc. | Dialysis solutions and methods |
| JP4882054B2 (ja) | 2000-09-13 | 2012-02-22 | 独立行政法人科学技術振興機構 | 腹膜透析液およびその調製法 |
| JP5564158B2 (ja) * | 2003-07-09 | 2014-07-30 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 亜硝酸塩によって特定の心臓血管状態を処置する方法 |
| US7362274B1 (en) * | 2004-07-09 | 2008-04-22 | Huan-Cheng Lien | Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna |
| US20070154570A1 (en) * | 2004-09-29 | 2007-07-05 | Miller Christopher C | Use of nitric oxide in the treatment and disinfection of biofilms |
| US7547637B2 (en) * | 2005-06-21 | 2009-06-16 | Intel Corporation | Methods for patterning a semiconductor film |
| US20090304600A1 (en) | 2008-06-09 | 2009-12-10 | Anupkumar Shetty | Intradialytic administration of sodium thiosulfate |
| US8568793B2 (en) | 2009-02-11 | 2013-10-29 | Hope Medical Enterprises, Inc. | Sodium nitrite-containing pharmaceutical compositions |
| AU2010270605B2 (en) | 2009-07-08 | 2014-07-31 | Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals | Sodium thiosulfate-containing pharmaceutical compositions |
| CA2844759A1 (en) * | 2011-08-11 | 2013-02-14 | Nathan S. Bryan | Method of measuring and monitoring in vivo nitrite levels |
| WO2013112582A1 (en) | 2012-01-23 | 2013-08-01 | Santalis Pharmaceuticals Inc. | Sandalwood oil and its uses related to clostridium infections |
| JP5486069B1 (ja) | 2012-11-05 | 2014-05-07 | 旭 酒井 | 透析装置 |
| US20140350097A1 (en) | 2013-05-23 | 2014-11-27 | Medinox,Inc. | Treatment of hypotension associated with hemodialysis |
| JP6183832B2 (ja) * | 2013-06-19 | 2017-08-23 | 扶桑薬品工業株式会社 | 酸化ストレス抑制型透析用剤およびその調製方法 |
| BR112019018861A2 (pt) * | 2017-03-08 | 2023-10-10 | Hope Medical Entpr Inc Dba Hope Pharmaceuticals | Uso de nitrito de sódio, método para manter os níveis fisiológicos de nitrito, prevenir enfarte do miocárdio, prevenir morte súbita cardíaca, prevenir acidente vascular cerebral, doenças cardiovasculares, pressão alta, solução aquosa |
-
2018
- 2018-03-06 BR BR112019018861A patent/BR112019018861A2/pt unknown
- 2018-03-06 IL IL312092A patent/IL312092B2/en unknown
- 2018-03-06 KR KR1020257002477A patent/KR20250017763A/ko active Pending
- 2018-03-06 EP EP24182318.6A patent/EP4406595A3/en active Pending
- 2018-03-06 ES ES18763384T patent/ES2986444T3/es active Active
- 2018-03-06 KR KR1020247008154A patent/KR102706379B1/ko active Active
- 2018-03-06 AU AU2018231016A patent/AU2018231016B2/en active Active
- 2018-03-06 JP JP2019548431A patent/JP7314050B2/ja active Active
- 2018-03-06 EP EP18763384.7A patent/EP3592342B1/en active Active
- 2018-03-06 KR KR1020247030224A patent/KR102760913B1/ko active Active
- 2018-03-06 NZ NZ797744A patent/NZ797744A/en unknown
- 2018-03-06 NZ NZ797740A patent/NZ797740A/en unknown
- 2018-03-06 IL IL301302A patent/IL301302B2/en unknown
- 2018-03-06 NZ NZ789172A patent/NZ789172A/en unknown
- 2018-03-06 CA CA3055105A patent/CA3055105A1/en active Pending
- 2018-03-06 NZ NZ756701A patent/NZ756701A/en unknown
- 2018-03-06 WO PCT/US2018/021053 patent/WO2018165098A1/en not_active Ceased
- 2018-03-06 KR KR1020197029157A patent/KR102647803B1/ko active Active
- 2018-03-07 TW TW112109906A patent/TWI835595B/zh active
- 2018-03-07 US US15/914,353 patent/US10328099B2/en active Active
- 2018-03-07 TW TW107107745A patent/TWI798203B/zh active
- 2018-03-07 TW TW113105276A patent/TWI888012B/zh active
- 2018-03-07 AR ARP180100529A patent/AR111166A1/es not_active Application Discontinuation
-
2019
- 2019-05-03 US US16/403,428 patent/US10898512B2/en active Active
- 2019-08-23 PH PH12019501950A patent/PH12019501950A1/en unknown
- 2019-08-23 IL IL268882A patent/IL268882B/en unknown
- 2019-08-28 ZA ZA2019/05679A patent/ZA201905679B/en unknown
-
2020
- 2020-11-23 US US17/102,411 patent/US11564938B2/en active Active
-
2021
- 2021-07-07 IL IL284684A patent/IL284684B2/en unknown
-
2022
- 2022-07-29 ZA ZA2022/08504A patent/ZA202208504B/en unknown
-
2023
- 2023-01-03 US US18/092,569 patent/US12011456B2/en active Active
- 2023-07-12 JP JP2023114331A patent/JP7551858B2/ja active Active
- 2023-07-25 ZA ZA2023/07367A patent/ZA202307367B/en unknown
-
2024
- 2024-05-08 US US18/658,338 patent/US20240285677A1/en active Pending
- 2024-05-28 AU AU2024203535A patent/AU2024203535B2/en active Active
- 2024-09-04 JP JP2024152352A patent/JP7765687B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020510014A5 (https=) | ||
| JP2020510680A5 (https=) | ||
| Langston et al. | Applications and outcome of hemodialysis in cats: a review of 29 cases | |
| Flanigan et al. | Regional hemodialysis anticoagulation: hypertonic tri-sodium citrate or anticoagulant citrate dextrose-A | |
| Filis et al. | Hyperchloraemia in sepsis | |
| Zhang et al. | Simplified regional citrate anticoagulation using a calcium-containing replacement solution for continuous venovenous hemofiltration | |
| Borkan | Extracorporeal therapies for acute intoxications | |
| Hayes et al. | Intradialytic hypotension | |
| Ortega et al. | Contrast-induced nephropathy: pathogenesis and new therapeutic options for prevention | |
| Bailey et al. | Comparison of intermittent haemodialysis, prolonged intermittent renal replacement therapy and continuous renal replacement haemofiltration for lithium toxicity: a case report | |
| Charra et al. | Survival in Dialysis and | |
| Schrier | Manual of nephrology | |
| McCunn et al. | Continuous renal replacement therapy in patients following traumatic injury | |
| Simpson et al. | Ultrafiltration in diuretic-resistant cardiac failure | |
| Weisbord et al. | Iodinated contrast media and the role of renal replacement therapy | |
| ES2862649T3 (es) | Fluido de diálisis sin calcio | |
| McCullough | Prevention of cardiorenal syndromes | |
| US20050142212A1 (en) | Parenteral administration of pyrophosphate for prevention or treatment of phosphate or pyrophosphate depletion | |
| BARRETO | 47 Drug Dosing in Kidney Dysfunction | |
| Leunissen et al. | Acute dialysis complications | |
| Ettema | Hemodynamic stability during hemodialysis: A role for vasopressin? | |
| Thornhill et al. | Current Status Of Hemodialysis In Veterinary Medicine And The Development Of The Canine Animal Model For Hemodialysis-Related Disorders In Man | |
| ES2724933A1 (es) | Terapia combinada con melatonina para la reducción de la presión intraocular | |
| Ksiąźek et al. | Sympathetic activity, plasma renin activity (PRA) and kininogen levels in patients haemodialysed with acetate and bicarbonate | |
| Foringer et al. | Potassium disorders |