JP7314050B2 - 亜硝酸ナトリウムの透析中の使用 - Google Patents

亜硝酸ナトリウムの透析中の使用 Download PDF

Info

Publication number
JP7314050B2
JP7314050B2 JP2019548431A JP2019548431A JP7314050B2 JP 7314050 B2 JP7314050 B2 JP 7314050B2 JP 2019548431 A JP2019548431 A JP 2019548431A JP 2019548431 A JP2019548431 A JP 2019548431A JP 7314050 B2 JP7314050 B2 JP 7314050B2
Authority
JP
Japan
Prior art keywords
dialysate
nitrite
spiked
pharmaceutical
dialyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019548431A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020510014A (ja
JP2020510014A5 (https=
Inventor
スヘルマン クライグ
Original Assignee
ホープ メディカル エンタープライズ インコーポレイテッド ディー.ビー.エー. ホープ ファーマシューティカルズ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ホープ メディカル エンタープライズ インコーポレイテッド ディー.ビー.エー. ホープ ファーマシューティカルズ filed Critical ホープ メディカル エンタープライズ インコーポレイテッド ディー.ビー.エー. ホープ ファーマシューティカルズ
Publication of JP2020510014A publication Critical patent/JP2020510014A/ja
Publication of JP2020510014A5 publication Critical patent/JP2020510014A5/ja
Priority to JP2023114331A priority Critical patent/JP7551858B2/ja
Application granted granted Critical
Publication of JP7314050B2 publication Critical patent/JP7314050B2/ja
Priority to JP2024152352A priority patent/JP7765687B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • A61M1/1656Apparatus for preparing dialysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019548431A 2017-03-08 2018-03-06 亜硝酸ナトリウムの透析中の使用 Active JP7314050B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023114331A JP7551858B2 (ja) 2017-03-08 2023-07-12 亜硝酸ナトリウムの透析中の使用
JP2024152352A JP7765687B2 (ja) 2017-03-08 2024-09-04 亜硝酸ナトリウムの透析中の使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762468857P 2017-03-08 2017-03-08
US62/468,857 2017-03-08
PCT/US2018/021053 WO2018165098A1 (en) 2017-03-08 2018-03-06 Intradialytic use of sodium nitrite

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023114331A Division JP7551858B2 (ja) 2017-03-08 2023-07-12 亜硝酸ナトリウムの透析中の使用

Publications (3)

Publication Number Publication Date
JP2020510014A JP2020510014A (ja) 2020-04-02
JP2020510014A5 JP2020510014A5 (https=) 2021-04-22
JP7314050B2 true JP7314050B2 (ja) 2023-07-25

Family

ID=63445965

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019548431A Active JP7314050B2 (ja) 2017-03-08 2018-03-06 亜硝酸ナトリウムの透析中の使用
JP2023114331A Active JP7551858B2 (ja) 2017-03-08 2023-07-12 亜硝酸ナトリウムの透析中の使用
JP2024152352A Active JP7765687B2 (ja) 2017-03-08 2024-09-04 亜硝酸ナトリウムの透析中の使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023114331A Active JP7551858B2 (ja) 2017-03-08 2023-07-12 亜硝酸ナトリウムの透析中の使用
JP2024152352A Active JP7765687B2 (ja) 2017-03-08 2024-09-04 亜硝酸ナトリウムの透析中の使用

Country Status (15)

Country Link
US (5) US10328099B2 (https=)
EP (2) EP4406595A3 (https=)
JP (3) JP7314050B2 (https=)
KR (4) KR20250017763A (https=)
AR (1) AR111166A1 (https=)
AU (2) AU2018231016B2 (https=)
BR (1) BR112019018861A2 (https=)
CA (1) CA3055105A1 (https=)
ES (1) ES2986444T3 (https=)
IL (4) IL312092B2 (https=)
NZ (4) NZ797744A (https=)
PH (1) PH12019501950A1 (https=)
TW (3) TWI835595B (https=)
WO (1) WO2018165098A1 (https=)
ZA (3) ZA201905679B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019018861A2 (pt) * 2017-03-08 2023-10-10 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Uso de nitrito de sódio, método para manter os níveis fisiológicos de nitrito, prevenir enfarte do miocárdio, prevenir morte súbita cardíaca, prevenir acidente vascular cerebral, doenças cardiovasculares, pressão alta, solução aquosa
IL268883B (en) 2017-03-08 2022-09-01 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Intradialytic use of sodium thiosulfate
EP4005611B1 (en) * 2019-07-22 2025-11-26 School Juridical Person The Kitasato Institute Dialysis device
US20230149732A1 (en) * 2021-11-17 2023-05-18 Wake Forest University Health Sciences Combined nitrite and light treatment to prevent device thrombosis
CN120456938A (zh) 2022-12-16 2025-08-08 费森尤斯医疗保健控股公司 用于在透析中使用一氧化氮的系统和方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015003871A (ja) 2013-06-19 2015-01-08 扶桑薬品工業株式会社 酸化ストレス抑制型透析用剤およびその調製方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218900B1 (en) 1985-09-10 1992-01-22 Research Corporation Technologies, Inc. Osmotic agents for peritoneal dialysis
US6380163B1 (en) 1992-12-22 2002-04-30 Baxter International Inc. Peritoneal dialysis solutions with polypeptides
FI98538C (fi) 1993-10-20 1997-07-10 Enso Gutzeit Oy Menetelmä natriumhydroksidin valmistamiseksi valkolipeästä
US6306836B1 (en) 1994-01-21 2001-10-23 Baxter International Inc. Peritoneal dialysis solutions containing maltodextrins and amino acids
US6436969B1 (en) 1995-09-12 2002-08-20 Kansas University Medical Center Research Institute Inc. Dialysis solutions and methods
JP4882054B2 (ja) 2000-09-13 2012-02-22 独立行政法人科学技術振興機構 腹膜透析液およびその調製法
JP5564158B2 (ja) * 2003-07-09 2014-07-30 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 亜硝酸塩によって特定の心臓血管状態を処置する方法
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
US7547637B2 (en) * 2005-06-21 2009-06-16 Intel Corporation Methods for patterning a semiconductor film
US20090304600A1 (en) 2008-06-09 2009-12-10 Anupkumar Shetty Intradialytic administration of sodium thiosulfate
US8568793B2 (en) 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
AU2010270605B2 (en) 2009-07-08 2014-07-31 Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals Sodium thiosulfate-containing pharmaceutical compositions
CA2844759A1 (en) * 2011-08-11 2013-02-14 Nathan S. Bryan Method of measuring and monitoring in vivo nitrite levels
WO2013112582A1 (en) 2012-01-23 2013-08-01 Santalis Pharmaceuticals Inc. Sandalwood oil and its uses related to clostridium infections
JP5486069B1 (ja) 2012-11-05 2014-05-07 旭 酒井 透析装置
US20140350097A1 (en) 2013-05-23 2014-11-27 Medinox,Inc. Treatment of hypotension associated with hemodialysis
BR112019018861A2 (pt) * 2017-03-08 2023-10-10 Hope Medical Entpr Inc Dba Hope Pharmaceuticals Uso de nitrito de sódio, método para manter os níveis fisiológicos de nitrito, prevenir enfarte do miocárdio, prevenir morte súbita cardíaca, prevenir acidente vascular cerebral, doenças cardiovasculares, pressão alta, solução aquosa

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015003871A (ja) 2013-06-19 2015-01-08 扶桑薬品工業株式会社 酸化ストレス抑制型透析用剤およびその調製方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Free Radical Biology and Medicine,2013年,Vol.58,pp.46-51
Nitric Oxide,2016年,Vol.58,pp.1-9
化学工学論文集,1989年,Vol.15, No.6,pp.1102-1108

Also Published As

Publication number Publication date
TW202421096A (zh) 2024-06-01
US12011456B2 (en) 2024-06-18
AR111166A1 (es) 2019-06-12
AU2024203535A1 (en) 2024-06-20
TWI888012B (zh) 2025-06-21
KR20250017763A (ko) 2025-02-04
IL312092A (en) 2024-06-01
TW201836594A (zh) 2018-10-16
WO2018165098A1 (en) 2018-09-13
US20180256637A1 (en) 2018-09-13
IL284684B2 (en) 2023-08-01
AU2018231016B2 (en) 2024-03-07
IL268882A (en) 2019-10-31
JP2024174935A (ja) 2024-12-17
ZA202208504B (en) 2024-01-31
KR102706379B1 (ko) 2024-09-19
EP3592342B1 (en) 2024-06-19
IL284684A (en) 2021-08-31
IL268882B (en) 2021-07-29
IL312092B1 (en) 2025-04-01
IL301302A (en) 2023-05-01
US20240285677A1 (en) 2024-08-29
US20190255098A1 (en) 2019-08-22
ZA201905679B (en) 2023-02-22
CA3055105A1 (en) 2018-09-13
US11564938B2 (en) 2023-01-31
US20210077524A1 (en) 2021-03-18
EP4406595A2 (en) 2024-07-31
IL301302B2 (en) 2024-09-01
KR102760913B1 (ko) 2025-02-03
ES2986444T3 (es) 2024-11-11
ZA202307367B (en) 2024-11-27
BR112019018861A2 (pt) 2023-10-10
US20230256005A1 (en) 2023-08-17
IL301302B1 (en) 2024-05-01
IL284684B1 (en) 2023-04-01
PH12019501950A1 (en) 2020-06-15
JP2023134621A (ja) 2023-09-27
US10328099B2 (en) 2019-06-25
TW202325265A (zh) 2023-07-01
US10898512B2 (en) 2021-01-26
JP2020510014A (ja) 2020-04-02
JP7551858B2 (ja) 2024-09-17
KR20190130588A (ko) 2019-11-22
NZ756701A (en) 2022-07-01
TWI798203B (zh) 2023-04-11
KR20240038812A (ko) 2024-03-25
KR102647803B1 (ko) 2024-03-15
AU2024203535B2 (en) 2026-04-23
NZ797740A (en) 2026-02-27
EP4406595A3 (en) 2024-10-30
NZ789172A (en) 2026-02-27
KR20240137711A (ko) 2024-09-20
EP3592342A1 (en) 2020-01-15
NZ797744A (en) 2026-02-27
AU2018231016A1 (en) 2019-09-19
TWI835595B (zh) 2024-03-11
EP3592342A4 (en) 2020-12-23
IL312092B2 (en) 2025-08-01
JP7765687B2 (ja) 2025-11-07

Similar Documents

Publication Publication Date Title
JP7765687B2 (ja) 亜硝酸ナトリウムの透析中の使用
JP7642878B2 (ja) チオ硫酸ナトリウムの透析中の使用
TWI915123B (zh) 包含硫代硫酸鈉之醫藥組合物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210304

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210304

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220308

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220606

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220720

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20220720

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221004

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20221227

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230403

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230613

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230712

R150 Certificate of patent or registration of utility model

Ref document number: 7314050

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150