JP2020507760A5 - - Google Patents
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- Publication number
- JP2020507760A5 JP2020507760A5 JP2019541330A JP2019541330A JP2020507760A5 JP 2020507760 A5 JP2020507760 A5 JP 2020507760A5 JP 2019541330 A JP2019541330 A JP 2019541330A JP 2019541330 A JP2019541330 A JP 2019541330A JP 2020507760 A5 JP2020507760 A5 JP 2020507760A5
- Authority
- JP
- Japan
- Prior art keywords
- pancreatic cancer
- biomarkers
- optionally
- sample
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000090 biomarker Substances 0.000 claims 27
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 26
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 26
- 201000002528 pancreatic cancer Diseases 0.000 claims 26
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 26
- 238000000034 method Methods 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 6
- 239000011230 binding agent Substances 0.000 claims 6
- 239000013068 control sample Substances 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 208000009956 adenocarcinoma Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 108010028778 Complement C4 Proteins 0.000 claims 3
- 108010028773 Complement C5 Proteins 0.000 claims 3
- 102100031506 Complement C5 Human genes 0.000 claims 3
- 229960002685 biotin Drugs 0.000 claims 3
- 235000020958 biotin Nutrition 0.000 claims 3
- 239000011616 biotin Substances 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 208000000668 Chronic Pancreatitis Diseases 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 206010033649 Pancreatitis chronic Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 239000000975 dye Substances 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 230000003211 malignant effect Effects 0.000 claims 2
- 201000008129 pancreatic ductal adenocarcinoma Diseases 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 206010052747 Adenocarcinoma pancreas Diseases 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 206010073365 Intraductal papillary mucinous carcinoma of pancreas Diseases 0.000 claims 1
- 206010055006 Pancreatic sarcoma Diseases 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 208000022669 mucinous neoplasm Diseases 0.000 claims 1
- 239000013642 negative control Substances 0.000 claims 1
- 201000002526 pancreas sarcoma Diseases 0.000 claims 1
- 201000002094 pancreatic adenocarcinoma Diseases 0.000 claims 1
- 201000004754 pancreatic intraductal papillary-mucinous neoplasm Diseases 0.000 claims 1
- 210000004923 pancreatic tissue Anatomy 0.000 claims 1
- 239000002953 phosphate buffered saline Substances 0.000 claims 1
- 239000013641 positive control Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1701572.8A GB201701572D0 (en) | 2017-01-31 | 2017-01-31 | Methods, arrays and uses thereof |
| GB1701572.8 | 2017-01-31 | ||
| PCT/EP2018/052423 WO2018141804A1 (en) | 2017-01-31 | 2018-01-31 | Methods, arrays and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020507760A JP2020507760A (ja) | 2020-03-12 |
| JP2020507760A5 true JP2020507760A5 (cg-RX-API-DMAC10.html) | 2021-03-18 |
Family
ID=58462729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541330A Pending JP2020507760A (ja) | 2017-01-31 | 2018-01-31 | 方法、アレイ、およびそれらの使用 |
Country Status (13)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008231575A1 (en) * | 2007-03-27 | 2008-10-02 | Immunovia Ab | Protein signature/markers for the detection of adenocarcinoma |
| CA3142634A1 (en) | 2019-07-03 | 2021-01-07 | Crystal Bioscience Inc. | Anti-b7-h3 antibody and methods of use thereof |
| KR102289278B1 (ko) * | 2019-07-09 | 2021-08-13 | 주식회사 베르티스 | 췌장암 진단용 바이오마커 패널 및 그 용도 |
| US20230055143A1 (en) * | 2019-12-20 | 2023-02-23 | Medimmune, Llc | Compositions and Methods of Treating Cancer with Chimeric Antigen Receptors Targeting Glypican 3 |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| CA3214598A1 (en) * | 2021-03-26 | 2022-09-29 | BioNTech SE | Combination therapy with an anti-ca19-9 antibody and folfirinox in the treatment of cancer |
| CN113336851B (zh) * | 2021-06-30 | 2021-12-24 | 徐州医科大学 | 新型全人源抗人b7h3抗体、包含所述抗体的组合物及其应用 |
| WO2026028902A1 (ja) * | 2024-08-01 | 2026-02-05 | 学校法人慈恵大学 | 診断薬、膵癌診断キット、検出方法、マーカー、抗膵癌剤、及び膵癌治療用組成物 |
| CN120177800B (zh) * | 2025-05-23 | 2025-10-10 | 四川大学 | 血液生物标志物cfp在制备急性胰腺炎诊断试剂的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US8632983B2 (en) * | 2005-04-15 | 2014-01-21 | Van Andel Research Institute | Biomarkers for pancreatic cancer and diagnostic methods |
| AU2008231575A1 (en) | 2007-03-27 | 2008-10-02 | Immunovia Ab | Protein signature/markers for the detection of adenocarcinoma |
| CN103476428B (zh) * | 2010-09-09 | 2016-10-26 | 北京同为时代生物技术有限公司 | 用于诊断上皮源性癌症的血液标志物及其单克隆抗体 |
| GB201103726D0 (en) | 2011-03-04 | 2011-04-20 | Immunovia Ab | Method, array and use thereof |
| GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| GB201516801D0 (en) * | 2015-09-22 | 2015-11-04 | Immunovia Ab | Method, array and use thereof |
-
2017
- 2017-01-31 GB GBGB1701572.8A patent/GB201701572D0/en not_active Ceased
-
2018
- 2018-01-31 RU RU2019123695A patent/RU2019123695A/ru not_active Application Discontinuation
- 2018-01-31 AU AU2018214180A patent/AU2018214180A1/en not_active Abandoned
- 2018-01-31 MX MX2019008911A patent/MX2019008911A/es unknown
- 2018-01-31 JP JP2019541330A patent/JP2020507760A/ja active Pending
- 2018-01-31 WO PCT/EP2018/052423 patent/WO2018141804A1/en not_active Ceased
- 2018-01-31 CN CN201880009309.3A patent/CN110325860A/zh active Pending
- 2018-01-31 BR BR112019015633-0A patent/BR112019015633A2/pt not_active Application Discontinuation
- 2018-01-31 US US16/479,064 patent/US20190382849A1/en not_active Abandoned
- 2018-01-31 EP EP18703545.6A patent/EP3577464A1/en not_active Withdrawn
- 2018-01-31 KR KR1020197022175A patent/KR20190109422A/ko not_active Ceased
- 2018-01-31 CA CA3051968A patent/CA3051968A1/en not_active Abandoned
-
2019
- 2019-07-24 IL IL268244A patent/IL268244A/en unknown
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