JP2020507312A - 複数の宿主用の複数のｄｎａコンストラクトのアセンブリ及び編集のためのモジュラーユニバーサルプラスミド設計戦略 - Google Patents

複数の宿主用の複数のｄｎａコンストラクトのアセンブリ及び編集のためのモジュラーユニバーサルプラスミド設計戦略 Download PDF

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JP2020507312A
JP2020507312A JP2019539756A JP2019539756A JP2020507312A JP 2020507312 A JP2020507312 A JP 2020507312A JP 2019539756 A JP2019539756 A JP 2019539756A JP 2019539756 A JP2019539756 A JP 2019539756A JP 2020507312 A JP2020507312 A JP 2020507312A
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dna
crispr
ctag
sequence
modular
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チャイキンド，ブライアン
ロッサム，ヘンドリク マリヌス ヴァン
ロッサム，ヘンドリク マリヌス ヴァン
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Zymergen Inc
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3517—Marker; Tag

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  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019539756A 2017-02-10 2018-02-09 複数の宿主用の複数のｄｎａコンストラクトのアセンブリ及び編集のためのモジュラーユニバーサルプラスミド設計戦略 Withdrawn JP2020507312A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762457493P 2017-02-10 2017-02-10
US62/457,493 2017-02-10
PCT/US2018/017573 WO2018148511A1 (en) 2017-02-10 2018-02-09 A modular universal plasmid design strategy for the assembly and editing of multiple dna constructs for multiple hosts

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JP2020507312A true JP2020507312A (ja) 2020-03-12
JP2020507312A5 JP2020507312A5 (https=) 2021-03-25

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US (2) US11098305B2 (https=)
EP (1) EP3580337A4 (https=)
JP (1) JP2020507312A (https=)
KR (1) KR20190116282A (https=)
CN (1) CN110312797A (https=)
CA (1) CA3049989A1 (https=)
WO (1) WO2018148511A1 (https=)

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CA3107002A1 (en) 2018-08-15 2020-04-30 Zymergen Inc. Applications of crispri in high throughput metabolic engineering
WO2020206134A1 (en) 2019-04-04 2020-10-08 Regeneron Pharmaceuticals, Inc. Methods for scarless introduction of targeted modifications into targeting vectors
US12497609B2 (en) * 2019-10-14 2025-12-16 Yonsei University Biohealth Technology Holdings. Inc. Protospacer adjacent motif sequence and method for modifying target nucleic acid in genome of cell by using same
KR102178813B1 (ko) 2019-10-18 2020-11-13 주식회사 다우진유전자연구소 Dna 구조체를 적용한 간이 키트
CN115052980B (zh) * 2019-11-18 2024-09-10 苏州齐禾生科生物科技有限公司 衍生自黄杆菌的基因编辑系统
WO2021108324A1 (en) * 2019-11-27 2021-06-03 Technical University Of Denmark Constructs, compositions and methods thereof having improved genome editing efficiency and specificity
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CN113373130B (zh) * 2021-05-31 2023-12-22 复旦大学 Cas12蛋白、含有Cas12蛋白的基因编辑系统及应用
GB202117455D0 (en) * 2021-12-02 2022-01-19 Academisch Ziekenhuis Leiden Method of editing nucleic acid
KR20240169697A (ko) * 2022-04-08 2024-12-03 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 올리고뉴클레오티드를 포함한 폴리뉴클레오티드의 신규 생산 방법
CN116284436B (zh) * 2022-11-25 2026-04-07 广州美格生物科技有限公司 嵌合体TsCas12a蛋白及其制备方法和应用
CN119432813A (zh) * 2023-12-29 2025-02-14 武汉艾迪晶生物科技有限公司 Cas蛋白、组合蛋白、核酸分子、核糖核蛋白复合物、重组载体、转基因细胞及其应用
WO2025165780A1 (en) * 2024-02-01 2025-08-07 The Board Of Trustees Of The Leland Stanford Junior University Combinatorial gene editing and screening

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Publication number Publication date
US20210371856A1 (en) 2021-12-02
WO2018148511A1 (en) 2018-08-16
KR20190116282A (ko) 2019-10-14
CA3049989A1 (en) 2018-08-16
EP3580337A4 (en) 2020-12-02
US20200123540A1 (en) 2020-04-23
EP3580337A1 (en) 2019-12-18
US11098305B2 (en) 2021-08-24
CN110312797A (zh) 2019-10-08

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