JP2020505944A5 - - Google Patents
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- Publication number
- JP2020505944A5 JP2020505944A5 JP2019555724A JP2019555724A JP2020505944A5 JP 2020505944 A5 JP2020505944 A5 JP 2020505944A5 JP 2019555724 A JP2019555724 A JP 2019555724A JP 2019555724 A JP2019555724 A JP 2019555724A JP 2020505944 A5 JP2020505944 A5 JP 2020505944A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- protease variant
- protease
- amino acid
- kumamoricin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091005804 Peptidases Proteins 0.000 claims 19
- 239000004365 Protease Substances 0.000 claims 19
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 19
- 125000003275 alpha amino acid group Chemical group 0.000 claims 9
- 238000006467 substitution reaction Methods 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 230000002797 proteolythic effect Effects 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- LLEUXCDZPQOJMY-AAEUAGOBSA-N Glu-Trp Chemical compound C1=CC=C2C(C[C@H](NC(=O)[C@H](CCC(O)=O)N)C(O)=O)=CNC2=C1 LLEUXCDZPQOJMY-AAEUAGOBSA-N 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 239000003674 animal food additive Substances 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 238000013329 compounding Methods 0.000 claims 1
- 239000006052 feed supplement Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002703 mutagenesis Methods 0.000 claims 1
- 231100000350 mutagenesis Toxicity 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 108010014252 thymogen Proteins 0.000 claims 1
- 230000002047 thymogen Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022031591A JP7344329B2 (ja) | 2016-12-22 | 2022-03-02 | 安定なプロテアーゼ変異型 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16206367 | 2016-12-22 | ||
| EP16206367.1 | 2016-12-22 | ||
| PCT/EP2017/084452 WO2018115473A2 (en) | 2016-12-22 | 2017-12-22 | Stable protease variants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022031591A Division JP7344329B2 (ja) | 2016-12-22 | 2022-03-02 | 安定なプロテアーゼ変異型 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020505944A JP2020505944A (ja) | 2020-02-27 |
| JP2020505944A5 true JP2020505944A5 (https=) | 2021-02-04 |
| JP7035079B2 JP7035079B2 (ja) | 2022-03-14 |
Family
ID=57629395
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555724A Active JP7035079B2 (ja) | 2016-12-22 | 2017-12-22 | 安定なプロテアーゼ変異型 |
| JP2022031591A Active JP7344329B2 (ja) | 2016-12-22 | 2022-03-02 | 安定なプロテアーゼ変異型 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022031591A Active JP7344329B2 (ja) | 2016-12-22 | 2022-03-02 | 安定なプロテアーゼ変異型 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11396648B2 (https=) |
| EP (2) | EP4732675A2 (https=) |
| JP (2) | JP7035079B2 (https=) |
| KR (2) | KR102553627B1 (https=) |
| CN (1) | CN110325636A (https=) |
| AU (2) | AU2017380106B2 (https=) |
| BR (1) | BR112019012980A2 (https=) |
| CA (1) | CA3047868A1 (https=) |
| MX (2) | MX2019007287A (https=) |
| WO (1) | WO2018115473A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2023004807A (es) * | 2020-10-30 | 2023-05-10 | Univ Washington | Composiciones y metodos para el tratamiento de la celiaquia. |
| EP4469075A4 (en) | 2022-01-26 | 2025-09-10 | Digestiva Inc | METHODS AND COMPOSITIONS FOR STABILIZING BLOOD GLUCOSE |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1600141B1 (en) * | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| CA2882502A1 (en) | 2011-08-10 | 2013-02-14 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| US10266815B2 (en) * | 2013-08-14 | 2019-04-23 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| NZ737500A (en) * | 2015-06-08 | 2025-02-28 | Univ Washington | Compositions and methods for treating celiac sprue disease |
| ES3039968T3 (en) * | 2016-06-23 | 2025-10-28 | Ew Nutrition Gmbh | Feed composition comprising an acid protease |
-
2017
- 2017-12-22 AU AU2017380106A patent/AU2017380106B2/en active Active
- 2017-12-22 WO PCT/EP2017/084452 patent/WO2018115473A2/en not_active Ceased
- 2017-12-22 JP JP2019555724A patent/JP7035079B2/ja active Active
- 2017-12-22 US US16/471,507 patent/US11396648B2/en active Active
- 2017-12-22 KR KR1020197020123A patent/KR102553627B1/ko active Active
- 2017-12-22 KR KR1020237022708A patent/KR102686572B1/ko active Active
- 2017-12-22 BR BR112019012980-4A patent/BR112019012980A2/pt unknown
- 2017-12-22 EP EP26155457.0A patent/EP4732675A2/en active Pending
- 2017-12-22 CA CA3047868A patent/CA3047868A1/en active Pending
- 2017-12-22 MX MX2019007287A patent/MX2019007287A/es unknown
- 2017-12-22 CN CN201780087051.4A patent/CN110325636A/zh active Pending
- 2017-12-22 EP EP17835479.1A patent/EP3559225A2/en active Pending
-
2019
- 2019-06-19 MX MX2024000078A patent/MX2024000078A/es unknown
-
2022
- 2022-03-02 JP JP2022031591A patent/JP7344329B2/ja active Active
-
2024
- 2024-04-17 AU AU2024202526A patent/AU2024202526A1/en active Pending
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