MX2024000078A - Variantes de proteasas estables. - Google Patents
Variantes de proteasas estables.Info
- Publication number
- MX2024000078A MX2024000078A MX2024000078A MX2024000078A MX2024000078A MX 2024000078 A MX2024000078 A MX 2024000078A MX 2024000078 A MX2024000078 A MX 2024000078A MX 2024000078 A MX2024000078 A MX 2024000078A MX 2024000078 A MX2024000078 A MX 2024000078A
- Authority
- MX
- Mexico
- Prior art keywords
- kumamolisin
- seq
- set forth
- protease variants
- backbone
- Prior art date
Links
- 108091005804 Peptidases Proteins 0.000 title abstract 3
- 239000004365 Protease Substances 0.000 title abstract 3
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title abstract 3
- 230000002797 proteolythic effect Effects 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere a una variante de proteasa que es al menos 90% idéntica a la secuencia de aminoácidos de longitud completa de una estructura de la base Kumamolisina AS como se establece en cualquiera de las Id. de Sec. nos. de 1 - 3, mientras que mantiene la actividad proteolítica, o un fragmento, fracción o variante combinada de la misma que mantiene la actividad proteolítica, el cual variante de proteasa demuestra estabilidad alterada o mejorada en comparación con la Kumamolisina AS de tipo silvestre como se expone en Id. de Sec. no. 4, o la estructura de la base Kumamolisina AS como se establece en cualquiera de las Id. de Sec. nos. de 1 - 3.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16206367 | 2016-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2024000078A true MX2024000078A (es) | 2024-02-23 |
Family
ID=57629395
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007287A MX2019007287A (es) | 2016-12-22 | 2017-12-22 | Variantes de proteasas estables. |
| MX2024000078A MX2024000078A (es) | 2016-12-22 | 2019-06-19 | Variantes de proteasas estables. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019007287A MX2019007287A (es) | 2016-12-22 | 2017-12-22 | Variantes de proteasas estables. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11396648B2 (es) |
| EP (1) | EP3559225A2 (es) |
| JP (2) | JP7035079B2 (es) |
| KR (2) | KR102553627B1 (es) |
| CN (1) | CN110325636A (es) |
| AU (2) | AU2017380106B2 (es) |
| BR (1) | BR112019012980A2 (es) |
| CA (1) | CA3047868A1 (es) |
| MX (2) | MX2019007287A (es) |
| WO (1) | WO2018115473A2 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023548083A (ja) * | 2020-10-30 | 2023-11-15 | ユニヴァーシティ オブ ワシントン | セリアックスプルー病を治療するための組成物及び方法 |
| AU2023213894A1 (en) | 2022-01-26 | 2024-08-15 | Digestiva, Inc. | Blood glucose stabilizing methods and compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1600141B1 (en) * | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| ES2896489T3 (es) | 2011-08-10 | 2022-02-24 | Univ Washington Through Its Center For Commercialization | Composiciones y procedimientos para el tratamiento de la enfermedad esprúe celíaco |
| US10266815B2 (en) * | 2013-08-14 | 2019-04-23 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| MX2017015786A (es) | 2015-06-08 | 2018-12-11 | Univ Washington | Composiciones y metodos para tratar la enfermedad celiaca. |
| MX2018015697A (es) | 2016-06-23 | 2019-05-27 | Ew Nutrition Gmbh | Composición de alimentación que comprende una proteasa ácida. |
-
2017
- 2017-12-22 EP EP17835479.1A patent/EP3559225A2/en active Pending
- 2017-12-22 US US16/471,507 patent/US11396648B2/en active Active
- 2017-12-22 CA CA3047868A patent/CA3047868A1/en active Pending
- 2017-12-22 AU AU2017380106A patent/AU2017380106B2/en active Active
- 2017-12-22 CN CN201780087051.4A patent/CN110325636A/zh active Pending
- 2017-12-22 KR KR1020197020123A patent/KR102553627B1/ko active IP Right Grant
- 2017-12-22 KR KR1020237022708A patent/KR102686572B1/ko active IP Right Grant
- 2017-12-22 MX MX2019007287A patent/MX2019007287A/es unknown
- 2017-12-22 WO PCT/EP2017/084452 patent/WO2018115473A2/en unknown
- 2017-12-22 JP JP2019555724A patent/JP7035079B2/ja active Active
- 2017-12-22 BR BR112019012980-4A patent/BR112019012980A2/pt unknown
-
2019
- 2019-06-19 MX MX2024000078A patent/MX2024000078A/es unknown
-
2022
- 2022-03-02 JP JP2022031591A patent/JP7344329B2/ja active Active
-
2024
- 2024-04-17 AU AU2024202526A patent/AU2024202526A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017380106A1 (en) | 2019-07-04 |
| JP7344329B2 (ja) | 2023-09-13 |
| BR112019012980A2 (pt) | 2020-05-26 |
| KR20190095361A (ko) | 2019-08-14 |
| AU2024202526A1 (en) | 2024-05-30 |
| KR102553627B1 (ko) | 2023-07-07 |
| JP2020505944A (ja) | 2020-02-27 |
| US20190322994A1 (en) | 2019-10-24 |
| KR20230107898A (ko) | 2023-07-18 |
| MX2019007287A (es) | 2019-09-27 |
| CN110325636A (zh) | 2019-10-11 |
| CA3047868A1 (en) | 2018-06-28 |
| EP3559225A2 (en) | 2019-10-30 |
| JP2022081554A (ja) | 2022-05-31 |
| WO2018115473A3 (en) | 2019-01-31 |
| WO2018115473A2 (en) | 2018-06-28 |
| KR102686572B1 (ko) | 2024-07-19 |
| JP7035079B2 (ja) | 2022-03-14 |
| AU2017380106B2 (en) | 2024-05-09 |
| US11396648B2 (en) | 2022-07-26 |
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