CA3047868A1 - Stable protease variants - Google Patents

Stable protease variants Download PDF

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Publication number
CA3047868A1
CA3047868A1 CA3047868A CA3047868A CA3047868A1 CA 3047868 A1 CA3047868 A1 CA 3047868A1 CA 3047868 A CA3047868 A CA 3047868A CA 3047868 A CA3047868 A CA 3047868A CA 3047868 A1 CA3047868 A1 CA 3047868A1
Authority
CA
Canada
Prior art keywords
protease variant
kumamolisin
seq
protease
set forth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3047868A
Other languages
English (en)
French (fr)
Inventor
Andreas Michels
Andreas Scheidig
Christian Elend
Claudia KRAPP
Thomas Horn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EW Nutrition GmbH
Original Assignee
EW Nutrition GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EW Nutrition GmbH filed Critical EW Nutrition GmbH
Publication of CA3047868A1 publication Critical patent/CA3047868A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Fodder In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3047868A 2016-12-22 2017-12-22 Stable protease variants Pending CA3047868A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16206367.1 2016-12-22
EP16206367 2016-12-22
PCT/EP2017/084452 WO2018115473A2 (en) 2016-12-22 2017-12-22 Stable protease variants

Publications (1)

Publication Number Publication Date
CA3047868A1 true CA3047868A1 (en) 2018-06-28

Family

ID=57629395

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3047868A Pending CA3047868A1 (en) 2016-12-22 2017-12-22 Stable protease variants

Country Status (10)

Country Link
US (1) US11396648B2 (https=)
EP (2) EP3559225A2 (https=)
JP (2) JP7035079B2 (https=)
KR (2) KR102686572B1 (https=)
CN (1) CN110325636A (https=)
AU (2) AU2017380106B2 (https=)
BR (1) BR112019012980A2 (https=)
CA (1) CA3047868A1 (https=)
MX (2) MX2019007287A (https=)
WO (1) WO2018115473A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250064903A1 (en) * 2020-10-30 2025-02-27 University Of Washington Compositions and methods for treating celiac sprue disease
AU2023213894B2 (en) 2022-01-26 2025-04-10 Digestiva, Inc. Blood glucose stabilizing methods and compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1600141B1 (en) * 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries
JP6342802B2 (ja) 2011-08-10 2018-06-13 ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーションThe University Of Washington Through Its Center For Commercialization セリアックスプルー病を治療するための組成物および方法
WO2015023728A1 (en) * 2013-08-14 2015-02-19 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
HK1245129A1 (zh) * 2015-06-08 2018-08-24 University Of Washington 治疗腹腔疾病的组合物及方法
EP3475420B1 (en) 2016-06-23 2025-07-16 EW Nutrition GmbH Feed composition comprising an acid protease

Also Published As

Publication number Publication date
JP7344329B2 (ja) 2023-09-13
KR20190095361A (ko) 2019-08-14
WO2018115473A2 (en) 2018-06-28
JP2022081554A (ja) 2022-05-31
EP3559225A2 (en) 2019-10-30
CN110325636A (zh) 2019-10-11
JP2020505944A (ja) 2020-02-27
MX2019007287A (es) 2019-09-27
BR112019012980A2 (pt) 2020-05-26
EP4732675A2 (en) 2026-04-29
AU2017380106B2 (en) 2024-05-09
JP7035079B2 (ja) 2022-03-14
KR102686572B1 (ko) 2024-07-19
US11396648B2 (en) 2022-07-26
US20190322994A1 (en) 2019-10-24
WO2018115473A3 (en) 2019-01-31
MX2024000078A (es) 2024-02-23
AU2024202526A1 (en) 2024-05-30
KR20230107898A (ko) 2023-07-18
AU2017380106A1 (en) 2019-07-04
KR102553627B1 (ko) 2023-07-07

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