JP2020505350A5 - - Google Patents

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Publication number
JP2020505350A5
JP2020505350A5 JP2019538484A JP2019538484A JP2020505350A5 JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5 JP 2019538484 A JP2019538484 A JP 2019538484A JP 2019538484 A JP2019538484 A JP 2019538484A JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
combination according
acid sequence
constant region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2019538484A
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English (en)
Japanese (ja)
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JP2020505350A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2018/050348 external-priority patent/WO2018134782A1/en
Publication of JP2020505350A publication Critical patent/JP2020505350A/ja
Publication of JP2020505350A5 publication Critical patent/JP2020505350A5/ja
Ceased legal-status Critical Current

Links

JP2019538484A 2017-01-20 2018-01-19 癌の治療のための組合せ療法 Ceased JP2020505350A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762448460P 2017-01-20 2017-01-20
US62/448,460 2017-01-20
PCT/IB2018/050348 WO2018134782A1 (en) 2017-01-20 2018-01-19 Combination therapy for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2020505350A JP2020505350A (ja) 2020-02-20
JP2020505350A5 true JP2020505350A5 (enExample) 2021-02-25

Family

ID=61168137

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019538484A Ceased JP2020505350A (ja) 2017-01-20 2018-01-19 癌の治療のための組合せ療法

Country Status (10)

Country Link
US (1) US20220356222A9 (enExample)
EP (1) EP3570869A1 (enExample)
JP (1) JP2020505350A (enExample)
KR (1) KR20190105584A (enExample)
CN (1) CN110177568A (enExample)
AU (2) AU2018208883B2 (enExample)
CA (1) CA3046120A1 (enExample)
IL (1) IL266993A (enExample)
RU (1) RU2019122408A (enExample)
WO (1) WO2018134782A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
TW202028226A (zh) * 2018-12-13 2020-08-01 大陸商江蘇恆瑞醫藥股份有限公司 Il-15蛋白複合物聯合pd-l1抗體用於治療腫瘤疾病的用途
CN116574183A (zh) * 2019-08-22 2023-08-11 盛禾(中国)生物制药有限公司 多功能抗体、其制备及其用途
CR20220367A (es) * 2020-02-05 2022-08-30 Novartis Ag Célula cho que expresa heterodímeros il-15

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71691A (en) 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
US6569681B1 (en) 2000-03-14 2003-05-27 Transkaryotic Therapies, Inc. Methods of improving homologous recombination
EP3263581B2 (en) 2005-05-17 2025-07-09 University of Connecticut Compositions and methods for immunomodulation in an organism
WO2007070488A2 (en) 2005-12-12 2007-06-21 The Cbr Institute For Biomedical Research, Inc. Integrin alpha l i domain mutants with increased binding affinity
MX357691B (es) 2006-01-13 2018-07-19 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Il-15 y il-15r-alfa mejoradas para expresion en celulas mamiferas.
ES2642008T3 (es) 2007-05-11 2017-11-14 Altor Bioscience Corporation Moléculas de fusión y variantes de IL-15
EP2326531B2 (en) 2008-08-22 2021-01-13 Magna Seating Inc. Disc recliner with reduced backlash
EP3851459B1 (en) 2010-09-21 2024-05-01 Altor BioScience, LLC Multimeric il-15 soluble fusion molecules and methods of making and using same
EP2911684B1 (en) * 2012-10-24 2019-06-19 Novartis Ag Il-15r alpha forms, cells expressing il-15r alpha forms, and therapeutic uses of il-15r alpha and il-15/il-15r alpha complexes
ES2716685T3 (es) 2014-01-24 2019-06-14 Dana Farber Cancer Inst Inc Moléculas de anticuerpo para PD-1 y usos de las mismas
KR102762243B1 (ko) * 2014-06-30 2025-02-05 알토 바이오사이언스 엘엘씨 Il-15-베이즈드 분자 및 이의 사용 방법
UY36351A (es) * 2014-10-14 2016-06-01 Novartis Ag Moléculas de anticuerpo que se unen a pd-l1 y usos de las mismas

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