JP2020505350A5 - - Google Patents
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- Publication number
- JP2020505350A5 JP2020505350A5 JP2019538484A JP2019538484A JP2020505350A5 JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5 JP 2019538484 A JP2019538484 A JP 2019538484A JP 2019538484 A JP2019538484 A JP 2019538484A JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- combination according
- acid sequence
- constant region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448460P | 2017-01-20 | 2017-01-20 | |
| US62/448,460 | 2017-01-20 | ||
| PCT/IB2018/050348 WO2018134782A1 (en) | 2017-01-20 | 2018-01-19 | Combination therapy for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020505350A JP2020505350A (ja) | 2020-02-20 |
| JP2020505350A5 true JP2020505350A5 (enExample) | 2021-02-25 |
Family
ID=61168137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019538484A Ceased JP2020505350A (ja) | 2017-01-20 | 2018-01-19 | 癌の治療のための組合せ療法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220356222A9 (enExample) |
| EP (1) | EP3570869A1 (enExample) |
| JP (1) | JP2020505350A (enExample) |
| KR (1) | KR20190105584A (enExample) |
| CN (1) | CN110177568A (enExample) |
| AU (2) | AU2018208883B2 (enExample) |
| CA (1) | CA3046120A1 (enExample) |
| IL (1) | IL266993A (enExample) |
| RU (1) | RU2019122408A (enExample) |
| WO (1) | WO2018134782A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| CN112969718A (zh) * | 2018-12-13 | 2021-06-15 | 江苏恒瑞医药股份有限公司 | Il-15蛋白复合物联合pd-l1抗体用于治疗肿瘤疾病的用途 |
| SG11202111409YA (en) | 2019-05-20 | 2021-12-30 | Cytune Pharma | IL-2/IL-15Rßy AGONIST DOSING REGIMENS FOR TREATING CANCER OR INFECTIOUS DISEASES |
| CN116574183A (zh) | 2019-08-22 | 2023-08-11 | 盛禾(中国)生物制药有限公司 | 多功能抗体、其制备及其用途 |
| AU2021215893A1 (en) * | 2020-02-05 | 2022-08-25 | Novartis Ag | CHO cell expressing IL-15 heterodimers |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL71691A (en) | 1984-04-27 | 1991-04-15 | Yeda Res & Dev | Production of interferon-ypsilon |
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| TW402639B (en) | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
| US6569681B1 (en) | 2000-03-14 | 2003-05-27 | Transkaryotic Therapies, Inc. | Methods of improving homologous recombination |
| WO2007001677A2 (en) | 2005-05-17 | 2007-01-04 | University Of Connecticut | Compositions and methods for immunomodulation in an organism |
| WO2007070488A2 (en) | 2005-12-12 | 2007-06-21 | The Cbr Institute For Biomedical Research, Inc. | Integrin alpha l i domain mutants with increased binding affinity |
| EP2366787B1 (en) | 2006-01-13 | 2019-12-11 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Codon optimized IL-15 and IL-15R-Alpha genes for expression in mammalian cells |
| EP2388266B1 (en) | 2007-05-11 | 2014-04-23 | Altor BioScience Corporation | Fusion molecules and IL-15 variants |
| CA2727953C (en) | 2008-08-22 | 2017-05-16 | Magna Seating Inc. | Disc recliner with reduced backlash |
| JP6251570B2 (ja) | 2010-09-21 | 2017-12-20 | アルター・バイオサイエンス・コーポレーション | 多量体ｉｌ−１５可溶性融合分子並びにその製造及び使用方法 |
| US20150359853A1 (en) * | 2012-10-24 | 2015-12-17 | Admune Therapeutics Llc | Il-15r alpha forms, cells expressing il-15r alpha forms, and therapeutic uses of il-15r alpha and il-15/il-15r alpha complexes |
| UA122479C2 (uk) | 2014-01-24 | 2020-11-25 | Дана-Фарбер Кенсер Інстітьют, Інк. | Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1) |
| CA2953816C (en) * | 2014-06-30 | 2022-03-15 | Altor Bioscience Corporation | Il-15-based molecules and methods of use thereof |
| SG11201702401RA (en) * | 2014-10-14 | 2017-04-27 | Novartis Ag | Antibody molecules to pd-l1 and uses thereof |
-
2018
- 2018-01-19 EP EP18703630.6A patent/EP3570869A1/en not_active Withdrawn
- 2018-01-19 RU RU2019122408A patent/RU2019122408A/ru unknown
- 2018-01-19 CN CN201880007116.4A patent/CN110177568A/zh active Pending
- 2018-01-19 CA CA3046120A patent/CA3046120A1/en active Pending
- 2018-01-19 WO PCT/IB2018/050348 patent/WO2018134782A1/en not_active Ceased
- 2018-01-19 AU AU2018208883A patent/AU2018208883B2/en not_active Ceased
- 2018-01-19 KR KR1020197020516A patent/KR20190105584A/ko not_active Ceased
- 2018-01-19 US US16/479,089 patent/US20220356222A9/en not_active Abandoned
- 2018-01-19 JP JP2019538484A patent/JP2020505350A/ja not_active Ceased
-
2019
- 2019-05-29 IL IL266993A patent/IL266993A/en unknown
-
2021
- 2021-05-04 AU AU2021202787A patent/AU2021202787A1/en not_active Abandoned
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