JP2020505350A5 - - Google Patents

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Publication number
JP2020505350A5
JP2020505350A5 JP2019538484A JP2019538484A JP2020505350A5 JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5 JP 2019538484 A JP2019538484 A JP 2019538484A JP 2019538484 A JP2019538484 A JP 2019538484A JP 2020505350 A5 JP2020505350 A5 JP 2020505350A5
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JP
Japan
Prior art keywords
seq
amino acid
combination according
acid sequence
constant region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2019538484A
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English (en)
Japanese (ja)
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JP2020505350A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2018/050348 external-priority patent/WO2018134782A1/en
Publication of JP2020505350A publication Critical patent/JP2020505350A/ja
Publication of JP2020505350A5 publication Critical patent/JP2020505350A5/ja
Ceased legal-status Critical Current

Links

JP2019538484A 2017-01-20 2018-01-19 癌の治療のための組合せ療法 Ceased JP2020505350A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762448460P 2017-01-20 2017-01-20
US62/448,460 2017-01-20
PCT/IB2018/050348 WO2018134782A1 (en) 2017-01-20 2018-01-19 Combination therapy for the treatment of cancer

Publications (2)

Publication Number Publication Date
JP2020505350A JP2020505350A (ja) 2020-02-20
JP2020505350A5 true JP2020505350A5 (enExample) 2021-02-25

Family

ID=61168137

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019538484A Ceased JP2020505350A (ja) 2017-01-20 2018-01-19 癌の治療のための組合せ療法

Country Status (10)

Country Link
US (1) US20220356222A9 (enExample)
EP (1) EP3570869A1 (enExample)
JP (1) JP2020505350A (enExample)
KR (1) KR20190105584A (enExample)
CN (1) CN110177568A (enExample)
AU (2) AU2018208883B2 (enExample)
CA (1) CA3046120A1 (enExample)
IL (1) IL266993A (enExample)
RU (1) RU2019122408A (enExample)
WO (1) WO2018134782A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
US20220111008A1 (en) * 2018-12-13 2022-04-14 Jiangsu Hengrui Medicine Co., Ltd. Use of il-15 protein complex joint pd-l1 antibody for treating tumor diseases
CN116574183A (zh) 2019-08-22 2023-08-11 盛禾(中国)生物制药有限公司 多功能抗体、其制备及其用途
US20210244821A1 (en) * 2020-02-05 2021-08-12 Novartis Ag Cho cell expressed het il-15

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71691A (en) 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
US6569681B1 (en) 2000-03-14 2003-05-27 Transkaryotic Therapies, Inc. Methods of improving homologous recombination
PL1899364T5 (pl) 2005-05-17 2024-12-09 University Of Connecticut Kompozycje i sposoby immunomodulacji w organizmie
WO2007070488A2 (en) 2005-12-12 2007-06-21 The Cbr Institute For Biomedical Research, Inc. Integrin alpha l i domain mutants with increased binding affinity
EP1984505B1 (en) 2006-01-13 2019-12-25 The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health Codon optimized il-15 and il-15r-alpha genes for expression in mammalian cells
DK2160401T3 (da) 2007-05-11 2014-10-20 Altor Bioscience Corp Fusionsmolekyler og il-15-varianter
CN102099221B (zh) 2008-08-22 2014-01-29 麦格纳座椅公司 具有减小空转的盘形调角器
EP2619229B1 (en) 2010-09-21 2016-04-06 Altor BioScience Corporation Multimeric il-15 soluble fusion molecules and methods of making and using same
WO2014066527A2 (en) * 2012-10-24 2014-05-01 Admune Therapeutics Llc Il-15r alpha forms, cells expressing il-15r alpha forms, and therapeutic uses of il-15r alpha and il-15/il-15r alpha complexes
CA2935423C (en) 2014-01-24 2023-11-07 Dana-Farber Cancer Institute, Inc. Antibody molecules to pd-1 and uses thereof
KR102503476B1 (ko) * 2014-06-30 2023-02-24 알토 바이오사이언스 코포레이션 Il-15-베이즈드 분자 및 이의 사용 방법
WO2016061142A1 (en) * 2014-10-14 2016-04-21 Novartis Ag Antibody molecules to pd-l1 and uses thereof

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