JP2020504093A5 - - Google Patents
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- Publication number
- JP2020504093A5 JP2020504093A5 JP2019530027A JP2019530027A JP2020504093A5 JP 2020504093 A5 JP2020504093 A5 JP 2020504093A5 JP 2019530027 A JP2019530027 A JP 2019530027A JP 2019530027 A JP2019530027 A JP 2019530027A JP 2020504093 A5 JP2020504093 A5 JP 2020504093A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- use according
- moderate
- treatment
- vasomotor symptoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 20
- 208000024891 symptom Diseases 0.000 claims 8
- 230000001457 vasomotor Effects 0.000 claims 8
- 239000000902 placebo Substances 0.000 claims 5
- 229940068196 placebo Drugs 0.000 claims 5
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 4
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 3
- 229960005309 estradiol Drugs 0.000 claims 3
- 229930182833 estradiol Natural products 0.000 claims 3
- 125000005456 glyceride group Chemical group 0.000 claims 3
- 125000000400 lauroyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- 206010037660 Pyrexia Diseases 0.000 claims 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 235000012054 meals Nutrition 0.000 claims 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 2
- 229960003387 progesterone Drugs 0.000 claims 2
- 239000000186 progesterone Substances 0.000 claims 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- 206010030247 Oestrogen deficiency Diseases 0.000 claims 1
- 206010041349 Somnolence Diseases 0.000 claims 1
- 201000006828 endometrial hyperplasia Diseases 0.000 claims 1
- 239000002563 ionic surfactant Substances 0.000 claims 1
- 230000009245 menopause Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- -1 polyoxy Polymers 0.000 claims 1
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical compound CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000004291 uterus Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430339P | 2016-12-05 | 2016-12-05 | |
| US62/430,339 | 2016-12-05 | ||
| US201762481060P | 2017-04-03 | 2017-04-03 | |
| US62/481,060 | 2017-04-03 | ||
| PCT/US2017/064788 WO2018136161A1 (en) | 2016-12-05 | 2017-12-05 | Natural combination hormone replacement formulations and therapies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020504093A JP2020504093A (ja) | 2020-02-06 |
| JP2020504093A5 true JP2020504093A5 (cg-RX-API-DMAC10.html) | 2021-01-28 |
Family
ID=62908279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019530027A Pending JP2020504093A (ja) | 2016-12-05 | 2017-12-05 | 天然配合ホルモン補充製剤及び治療法 |
Country Status (11)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220105107A1 (en) * | 2020-10-01 | 2022-04-07 | Michael Liguori | Bioidentical progesterone cream infused with nanoemulsified cbd |
| GB202316026D0 (en) * | 2023-10-19 | 2023-12-06 | Theramex Hq Uk Ltd | Methods of prevention or treatment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
| US20020132801A1 (en) * | 2001-01-11 | 2002-09-19 | Schering Aktiengesellschaft | Drospirenone for hormone replacement therapy |
| US6901278B1 (en) * | 2002-01-29 | 2005-05-31 | Morris Notelovitz | Methods for reducing the risk of breast cancer in and improving the health of women |
| US20040062794A1 (en) * | 2002-09-30 | 2004-04-01 | Lee Shulman | 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy |
| US9301920B2 (en) * | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| AR100562A1 (es) * | 2014-05-22 | 2016-10-12 | Therapeuticsmd Inc | Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal |
-
2017
- 2017-12-05 MX MX2019006513A patent/MX2019006513A/es unknown
- 2017-12-05 BR BR112019011655A patent/BR112019011655A2/pt not_active IP Right Cessation
- 2017-12-05 AU AU2017394679A patent/AU2017394679A1/en not_active Abandoned
- 2017-12-05 JP JP2019530027A patent/JP2020504093A/ja active Pending
- 2017-12-05 WO PCT/US2017/064788 patent/WO2018136161A1/en not_active Ceased
- 2017-12-05 CN CN201780086119.7A patent/CN110290793A/zh active Pending
- 2017-12-05 CA CA3045024A patent/CA3045024A1/en not_active Abandoned
- 2017-12-05 RU RU2019115913A patent/RU2019115913A/ru not_active Application Discontinuation
-
2018
- 2018-02-02 KR KR1020197019625A patent/KR20200018383A/ko not_active Ceased
- 2018-02-02 EP EP17893482.4A patent/EP3548036A4/en not_active Withdrawn
-
2019
- 2019-06-02 IL IL267023A patent/IL267023A/en unknown
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