JP2020504080A5 - - Google Patents
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- JP2020504080A5 JP2020504080A5 JP2019524203A JP2019524203A JP2020504080A5 JP 2020504080 A5 JP2020504080 A5 JP 2020504080A5 JP 2019524203 A JP2019524203 A JP 2019524203A JP 2019524203 A JP2019524203 A JP 2019524203A JP 2020504080 A5 JP2020504080 A5 JP 2020504080A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- homodimer
- colitis
- use according
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022032190A JP7429726B2 (ja) | 2016-11-11 | 2022-03-02 | α４β７インテグリンを標的とする環状ペプチド多量体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662421117P | 2016-11-11 | 2016-11-11 | |
| US62/421,117 | 2016-11-11 | ||
| PCT/CA2017/000244 WO2018085921A1 (en) | 2016-11-11 | 2017-11-10 | CYCLIC PEPTIDES MULTIMERS TARGETING α4β7 INTEGRIN |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022032190A Division JP7429726B2 (ja) | 2016-11-11 | 2022-03-02 | α４β７インテグリンを標的とする環状ペプチド多量体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020504080A JP2020504080A (ja) | 2020-02-06 |
| JP2020504080A5 true JP2020504080A5 (https=) | 2020-12-17 |
| JP7035044B2 JP7035044B2 (ja) | 2022-03-14 |
Family
ID=62110102
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019524203A Active JP7035044B2 (ja) | 2016-11-11 | 2017-11-10 | α４β７インテグリンを標的とする環状ペプチド多量体 |
| JP2022032190A Active JP7429726B2 (ja) | 2016-11-11 | 2022-03-02 | α４β７インテグリンを標的とする環状ペプチド多量体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022032190A Active JP7429726B2 (ja) | 2016-11-11 | 2022-03-02 | α４β７インテグリンを標的とする環状ペプチド多量体 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11111273B2 (https=) |
| EP (2) | EP3939989A1 (https=) |
| JP (2) | JP7035044B2 (https=) |
| CN (1) | CN110088121A (https=) |
| CA (1) | CA3042576A1 (https=) |
| DK (1) | DK3538542T3 (https=) |
| ES (1) | ES2884107T3 (https=) |
| WO (1) | WO2018085921A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111273B2 (en) | 2016-11-11 | 2021-09-07 | Zealand Pharma A/S | Cyclic peptides multimers targeting alpha-4-beta-7 integrin |
| KR20230079464A (ko) | 2017-05-10 | 2023-06-07 | 질랜드 파마 에이/에스 | α4β7 인테그린을 타겟팅하는 호모데틱 사이클릭 펩타이드 |
| US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| US20230117920A1 (en) * | 2019-12-27 | 2023-04-20 | The University Of Tokyo | Library Construction Method, Cyclic Peptide, FXIIa Binder and IFNGR1 Binder |
| JP2021106565A (ja) * | 2019-12-27 | 2021-07-29 | 国立大学法人 東京大学 | ライブラリーの製造方法、環状ペプチド、ＦＸＩＩａ結合剤、及びＩＦＮＧＲ１結合剤 |
| EP4172177A1 (en) * | 2020-06-29 | 2023-05-03 | Zealand Pharma A/S | Compounds targeting alpha4-beta7 integrin |
| US11957761B2 (en) | 2021-12-20 | 2024-04-16 | Zealand Pharma A/S | Compounds having α4β7 integrin inhibition activity |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3219113A1 (de) | 1982-05-21 | 1983-11-24 | Bayer Ag, 5090 Leverkusen | Verwendung von n-substituierten 2,3-diaminocarbonsaeuren in arzneimitteln und ihre herstellung |
| ZA906188B (en) | 1989-08-10 | 1991-06-26 | Merrell Dow Pharma | Cyclic neurokinin a antagonists |
| US5296604A (en) | 1992-05-15 | 1994-03-22 | Miles Inc. | Proline derivatives and compositions for their use as inhibitors of HIV protease |
| US5705481A (en) | 1992-11-06 | 1998-01-06 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Cyclopeptides |
| IL109615A (en) | 1993-05-17 | 2000-12-06 | Fujisawa Pharmaceutical Co | Cyclic polypeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5693325A (en) | 1994-03-15 | 1997-12-02 | Molecumetics, Ltd. | Peptide vaccines and methods relating thereto |
| DE4415310A1 (de) | 1994-04-30 | 1995-11-02 | Merck Patent Gmbh | Cyclopeptide |
| WO1996000581A1 (en) | 1994-06-29 | 1996-01-11 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin alpha 4 beta 1 to vcam-1 or fibronectin |
| GB9524630D0 (en) | 1994-12-24 | 1996-01-31 | Zeneca Ltd | Chemical compounds |
| AU6311996A (en) | 1995-07-06 | 1997-02-05 | Zeneca Limited | Peptide inhibitors of fibronectine |
| US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
| US5696084A (en) | 1996-08-16 | 1997-12-09 | Abbott Laboratories | Amino-lipopetide antifungal agents |
| US6492553B1 (en) | 1998-01-29 | 2002-12-10 | Aventis Pharamaceuticals Inc. | Methods for preparing N-[(aliphatic or aromatic)carbonyl)]-2-aminoaetamide compounds and for cyclizing such compounds |
| US6960597B2 (en) | 2000-06-30 | 2005-11-01 | Orth-Mcneil Pharmaceutical, Inc. | Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists |
| DE10107707A1 (de) | 2001-02-19 | 2002-08-29 | Wilex Biotechnology Gmbh | Antagonisten für alpha¶4¶beta¶7¶-Integrin |
| US6667407B2 (en) | 2002-05-03 | 2003-12-23 | Bayer Polymers Llc | Process of making polyaziridines |
| WO2005105827A2 (en) | 2004-04-15 | 2005-11-10 | Proteolix, Inc. | Compounds for proteasome enzyme inhibition |
| US8143375B2 (en) | 2006-10-20 | 2012-03-27 | The Governing Council Of The University Of Toronto | Aziridine aldehydes, aziridine-conjugated amino derivatives, aziridine-conjugated biomolecules and processes for their preparation |
| EP1961759A1 (en) | 2007-02-21 | 2008-08-27 | Universita'degli Studi Di Milano | Integrin targeted cyclopeptide ligands, their preparation and use |
| EP2291390B1 (en) | 2008-05-22 | 2014-11-05 | Centre National de la Recherche Scientifique (CNRS) | New optically pure compounds for improved therapeutic efficiency |
| AU2010225426B2 (en) * | 2009-03-16 | 2015-09-03 | The Governing Council Of The University Of Toronto | Cyclic amino acid molecules and methods of preparing the same |
| US20120045393A1 (en) | 2009-03-17 | 2012-02-23 | Linder Karen E | Lhrh-ii peptide analogs |
| EP2556060A1 (en) | 2010-04-08 | 2013-02-13 | Ah Usa 42 Llc | Substituted 3,5- diphenyl-isoxazoline derivatives as insecticides and acaricides |
| WO2012113803A1 (en) | 2011-02-22 | 2012-08-30 | Leo Pharma A/S | A cyclic peptide and conjugate thereof for binding to keratinocytes |
| BR112014016736A8 (pt) * | 2012-01-27 | 2017-07-04 | Hoffmann La Roche | composto, composição farmacêutica, método para tratamento, uso de um composto e invenção |
| JP6152093B2 (ja) * | 2012-04-24 | 2017-06-21 | Ｅａファーマ株式会社 | スルホンアミド誘導体及びその医薬用途 |
| US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| PT3143037T (pt) | 2014-05-16 | 2021-09-24 | Protagonist Therapeutics Inc | Antagonistas peptídicos tioéter de integrina alfa4beta7 |
| KR20170108936A (ko) * | 2014-10-01 | 2017-09-27 | 프로타고니스트 테라퓨틱스, 인코포레이티드 | 신규한 α4β7 펩타이드 단량체 및 이량체 길항제 |
| EP3201217A4 (en) * | 2014-10-01 | 2018-07-18 | Protagonist Therapeutics Inc. | Novel cyclic monomer and dimer peptides having integrin antagonist activity |
| US11046695B2 (en) | 2015-11-11 | 2021-06-29 | Zealand Pharma A/S | Fragment synthesis of substituted cyclic peptides |
| US11111273B2 (en) * | 2016-11-11 | 2021-09-07 | Zealand Pharma A/S | Cyclic peptides multimers targeting alpha-4-beta-7 integrin |
-
2017
- 2017-11-10 US US16/348,103 patent/US11111273B2/en active Active
- 2017-11-10 WO PCT/CA2017/000244 patent/WO2018085921A1/en not_active Ceased
- 2017-11-10 CA CA3042576A patent/CA3042576A1/en active Pending
- 2017-11-10 EP EP21167845.3A patent/EP3939989A1/en active Pending
- 2017-11-10 EP EP17870529.9A patent/EP3538542B1/en active Active
- 2017-11-10 DK DK17870529.9T patent/DK3538542T3/da active
- 2017-11-10 ES ES17870529T patent/ES2884107T3/es active Active
- 2017-11-10 JP JP2019524203A patent/JP7035044B2/ja active Active
- 2017-11-10 CN CN201780076105.7A patent/CN110088121A/zh active Pending
-
2021
- 2021-04-19 US US17/234,488 patent/US11713338B2/en active Active
-
2022
- 2022-03-02 JP JP2022032190A patent/JP7429726B2/ja active Active
-
2023
- 2023-06-08 US US18/207,268 patent/US12077611B2/en active Active
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