JP2020503843A - 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 - Google Patents
抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 Download PDFInfo
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US62/411,508 | 2016-10-21 | ||
| PCT/US2017/057737 WO2018075974A2 (fr) | 2016-10-21 | 2017-10-20 | Anticorps anti-virus respiratoire syncytial, et leurs procédés de génération et d'utilisation |
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| JP2022024661A Pending JP2022065140A (ja) | 2016-10-21 | 2022-02-21 | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
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Country Status (6)
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| US (2) | US11485775B2 (fr) |
| EP (2) | EP3529270A2 (fr) |
| JP (2) | JP2020503843A (fr) |
| AU (1) | AU2017345786A1 (fr) |
| CA (1) | CA3040893A1 (fr) |
| WO (1) | WO2018075974A2 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| BR112019008063A2 (pt) | 2016-10-21 | 2019-07-02 | Adimab Llc | anticorpos contra o vírus sincicial anti-respiratório e métodos de sua geração e uso |
| JP2020503843A (ja) | 2016-10-21 | 2020-02-06 | アディマブ， エルエルシー | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
| WO2018075954A2 (fr) | 2016-10-21 | 2018-04-26 | Adimab, Llc | Anticorps contre le virus respiratoire syncytial et leurs méthodes de génération et d'utilisation |
| KR20220035368A (ko) * | 2019-06-07 | 2022-03-22 | 아디맵 엘엘씨 | 조작된 ph-의존성 항-cd3 항체, 및 이의 생성 및 사용 방법 |
| TW202115112A (zh) * | 2019-06-27 | 2021-04-16 | 德商百靈佳殷格翰國際股份有限公司 | 抗-angpt2抗體 |
| CA3200523A1 (fr) * | 2020-11-10 | 2022-05-19 | The Scripps Research Institute | Anticorps pour traitements aux opioides |
| WO2022150660A1 (fr) * | 2021-01-08 | 2022-07-14 | 10X Genomics, Inc. | Polypeptides de liaison à l'antigène spécifiques aux coronavirus et leurs utilisations |
| KR102531775B1 (ko) * | 2022-11-11 | 2023-05-15 | 대한민국 | Rsv f 항체 또는 이의 항원 결합 단편 |
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| US5824307A (en) | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
| ATE231002T1 (de) | 1992-09-16 | 2003-02-15 | Scripps Research Inst | Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus |
| EP0724602A4 (fr) | 1993-07-30 | 1998-12-23 | Oravax Inc | ANTICORPS IgA MONOCLONAL DIRIGE CONTRE LE VIRUS RESPIRATOIRE SYNCYTIAL |
| US5811524A (en) | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
| ATE194291T1 (de) | 1995-09-18 | 2000-07-15 | Intracel Corp | Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus |
| US20020141990A1 (en) * | 1996-11-01 | 2002-10-03 | Smithkline Beecham Corporation | Anti-RSV human monoclonal antibodies |
| WO2001032144A1 (fr) | 1999-10-29 | 2001-05-10 | Inhale Therapeutic Systems, Inc. | Compositions de poudre seche a dispersivite amelioree |
| ES2349348T3 (es) | 2000-01-27 | 2010-12-30 | Medimmune, Llc | Anticuerpos neutralizantes de rsv de ultra alta afinidad. |
| US7229619B1 (en) | 2000-11-28 | 2007-06-12 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| CA2401652A1 (fr) | 2000-03-01 | 2001-09-07 | Medimmune, Inc. | Anticorps de recombinaison hautement efficaces et procede de production de ceux-ci |
| AU2001241918A1 (en) | 2000-03-02 | 2001-09-12 | Med Immune, Inc. | Methods of enhancing activity of vaccines and vaccine compositions |
| EP1278546B1 (fr) | 2000-05-03 | 2010-02-10 | Medimmune, LLC | Polytherapie pour maladies respiratoires, dans laquelle des anticorps et des agents anti-inflammatoires sont utilises |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7179900B2 (en) | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
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| US6855493B2 (en) | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
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| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
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| WO2010081856A1 (fr) | 2009-01-14 | 2010-07-22 | Ablynx Nv | Administration par voie pulmonaire de domaines variables uniques d'immunoglobulines et de constructions associées |
| EP1613261A4 (fr) | 2003-04-09 | 2011-01-26 | Novo Nordisk As | Formation intracellulaire de conjugues de peptides |
| AU2004229527B2 (en) | 2003-04-11 | 2009-08-20 | Medimmune, Llc | Methods of preventing or treating respiratory conditions |
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| WO2005103081A2 (fr) | 2004-04-20 | 2005-11-03 | Genmab A/S | Anticorps monoclonaux humains diriges contre cd20 |
| WO2006034292A2 (fr) | 2004-09-21 | 2006-03-30 | Medimmune, Inc. | Anticorps dirige contre le virus respiratoire syncytial et procedes de production de vaccins associes |
| WO2006099481A2 (fr) | 2005-03-14 | 2006-09-21 | Medimmune, Inc. | Macromolecules comprenant une reticulation de thioether |
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| KR100938998B1 (ko) | 2008-01-08 | 2010-01-28 | (주) 에이프로젠 | 호흡기 신시티움 바이러스에 대한 항체 |
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- 2017-10-20 JP JP2019521445A patent/JP2020503843A/ja not_active Withdrawn
- 2017-10-20 WO PCT/US2017/057737 patent/WO2018075974A2/fr unknown
- 2017-10-20 EP EP17794177.0A patent/EP3529270A2/fr not_active Withdrawn
- 2017-10-20 AU AU2017345786A patent/AU2017345786A1/en active Pending
- 2017-10-20 EP EP21168818.9A patent/EP3974447A3/fr active Pending
- 2017-10-20 US US16/343,311 patent/US11485775B2/en active Active
- 2017-10-20 CA CA3040893A patent/CA3040893A1/fr active Pending
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2022
- 2022-02-21 JP JP2022024661A patent/JP2022065140A/ja active Pending
- 2022-09-20 US US17/933,725 patent/US20230192822A1/en active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2018075974A2 (fr) | 2018-04-26 |
| EP3974447A2 (fr) | 2022-03-30 |
| WO2018075974A3 (fr) | 2018-09-27 |
| US20230192822A1 (en) | 2023-06-22 |
| US11485775B2 (en) | 2022-11-01 |
| AU2017345786A1 (en) | 2019-05-23 |
| US20200223906A1 (en) | 2020-07-16 |
| CA3040893A1 (fr) | 2018-04-26 |
| JP2022065140A (ja) | 2022-04-26 |
| EP3974447A3 (fr) | 2022-09-07 |
| EP3529270A2 (fr) | 2019-08-28 |
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