JP2020503017A5 - - Google Patents
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- Publication number
- JP2020503017A5 JP2020503017A5 JP2019533110A JP2019533110A JP2020503017A5 JP 2020503017 A5 JP2020503017 A5 JP 2020503017A5 JP 2019533110 A JP2019533110 A JP 2019533110A JP 2019533110 A JP2019533110 A JP 2019533110A JP 2020503017 A5 JP2020503017 A5 JP 2020503017A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- compound according
- nucleoside
- crrna
- modified crrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662439828P | 2016-12-28 | 2016-12-28 | |
| US62/439,828 | 2016-12-28 | ||
| US201762491818P | 2017-04-28 | 2017-04-28 | |
| US62/491,818 | 2017-04-28 | ||
| US201762572361P | 2017-10-13 | 2017-10-13 | |
| US62/572,361 | 2017-10-13 | ||
| PCT/US2017/068642 WO2018125964A1 (en) | 2016-12-28 | 2017-12-28 | Modified crispr rna and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020503017A JP2020503017A (ja) | 2020-01-30 |
| JP2020503017A5 true JP2020503017A5 (cg-RX-API-DMAC10.html) | 2021-02-12 |
Family
ID=62710685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019533110A Pending JP2020503017A (ja) | 2016-12-28 | 2017-12-28 | 修飾ｃｒｉｓｐｒ ｒｎａ及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20190382751A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3562942A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2020503017A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2017388379A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3047330A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2018125964A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3652312A1 (en) | 2017-07-14 | 2020-05-20 | Editas Medicine, Inc. | Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites |
| AU2019291918B2 (en) | 2018-06-29 | 2025-06-12 | Editas Medicine, Inc. | Synthetic guide molecules, compositions and methods relating thereto |
| EP3983536A4 (en) * | 2019-06-14 | 2023-11-29 | Arbor Biotechnologies, Inc. | NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS |
| CA3198905A1 (en) * | 2020-10-19 | 2022-04-28 | Caribou Biosciences, Inc. | Dna-containing polynucleotides and guides for crispr type v systems, and methods of making and using the same |
| US20250325698A1 (en) * | 2022-04-13 | 2025-10-23 | Caribou Biosciences, Inc. | Therapeutic applications of crispr type v systems |
| JP2026523341A (ja) | 2023-05-15 | 2026-07-14 | エヌクロマ・バイオ，インコーポレーテッド | Ｈｂｖ遺伝子発現のエピジェネティック調節のための組成物および方法 |
| CN116732075B (zh) * | 2023-06-09 | 2024-03-08 | 江南大学 | 一种生产2′-岩藻糖基乳糖的多层动态调控系统及其应用 |
| WO2025212120A1 (en) * | 2024-04-05 | 2025-10-09 | Arbor Biotechnologies, Inc. | Chemical modifications of guide rnas for crispr nucleases |
| WO2025231432A1 (en) * | 2024-05-03 | 2025-11-06 | Caribou Biosciences, Inc. | In vivo gene editing with crispr systems |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105408483A (zh) * | 2013-03-15 | 2016-03-16 | 通用医疗公司 | 遗传和表观遗传调节蛋白至特定基因组基因座的rna引导的靶向 |
| WO2015200555A2 (en) * | 2014-06-25 | 2015-12-30 | Caribou Biosciences, Inc. | Rna modification to engineer cas9 activity |
| CA2969619A1 (en) * | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| AU2016211517B2 (en) * | 2015-01-28 | 2021-05-13 | Caribou Biosciences, Inc. | CRISPR hybrid DNA/RNA polynucleotides and methods of use |
| US9790490B2 (en) * | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| JP2018519811A (ja) * | 2015-06-29 | 2018-07-26 | アイオーニス ファーマシューティカルズ， インコーポレーテッドＩｏｎｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 修飾ｃｒｉｓｐｒ ｒｎａ及び修飾単一ｃｒｉｓｐｒ ｒｎａならびにその使用 |
| WO2017181107A2 (en) * | 2016-04-16 | 2017-10-19 | Ohio State Innovation Foundation | Modified cpf1 mrna, modified guide rna, and uses thereof |
| CN106244591A (zh) * | 2016-08-23 | 2016-12-21 | 苏州吉玛基因股份有限公司 | 修饰crRNA在CRISPR/Cpf1基因编辑系统中的应用 |
| CA3044101A1 (en) * | 2016-11-22 | 2018-05-31 | Integrated Dna Technologies, Inc. | Crispr/cpf1 systems and methods |
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2017
- 2017-12-28 AU AU2017388379A patent/AU2017388379A1/en not_active Abandoned
- 2017-12-28 US US16/470,464 patent/US20190382751A1/en not_active Abandoned
- 2017-12-28 JP JP2019533110A patent/JP2020503017A/ja active Pending
- 2017-12-28 WO PCT/US2017/068642 patent/WO2018125964A1/en not_active Ceased
- 2017-12-28 CA CA3047330A patent/CA3047330A1/en not_active Abandoned
- 2017-12-28 EP EP17886910.3A patent/EP3562942A4/en not_active Withdrawn