JP2020502121A5 - - Google Patents

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Publication number
JP2020502121A5
JP2020502121A5 JP2019531750A JP2019531750A JP2020502121A5 JP 2020502121 A5 JP2020502121 A5 JP 2020502121A5 JP 2019531750 A JP2019531750 A JP 2019531750A JP 2019531750 A JP2019531750 A JP 2019531750A JP 2020502121 A5 JP2020502121 A5 JP 2020502121A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
vasodilator
particles
subject
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019531750A
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English (en)
Japanese (ja)
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JP2020502121A (ja
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Priority claimed from PCT/US2017/066519 external-priority patent/WO2018112258A1/en
Publication of JP2020502121A publication Critical patent/JP2020502121A/ja
Publication of JP2020502121A5 publication Critical patent/JP2020502121A5/ja
Priority to JP2022197348A priority Critical patent/JP2023036678A/ja
Priority to JP2025019782A priority patent/JP2025065408A/ja
Pending legal-status Critical Current

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JP2019531750A 2016-12-14 2017-12-14 肺高血圧症および他の肺障害の処置のための方法および組成物 Pending JP2020502121A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022197348A JP2023036678A (ja) 2016-12-14 2022-12-09 肺高血圧症および他の肺障害の処置のための方法および組成物
JP2025019782A JP2025065408A (ja) 2016-12-14 2025-02-10 肺高血圧症および他の肺障害の処置のための方法および組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662434185P 2016-12-14 2016-12-14
US62/434,185 2016-12-14
PCT/US2017/066519 WO2018112258A1 (en) 2016-12-14 2017-12-14 Methods and compositions for treatment of pulmonary hypertension and other lung disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022197348A Division JP2023036678A (ja) 2016-12-14 2022-12-09 肺高血圧症および他の肺障害の処置のための方法および組成物

Publications (2)

Publication Number Publication Date
JP2020502121A JP2020502121A (ja) 2020-01-23
JP2020502121A5 true JP2020502121A5 (https=) 2021-01-28

Family

ID=60888760

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019531750A Pending JP2020502121A (ja) 2016-12-14 2017-12-14 肺高血圧症および他の肺障害の処置のための方法および組成物
JP2022197348A Pending JP2023036678A (ja) 2016-12-14 2022-12-09 肺高血圧症および他の肺障害の処置のための方法および組成物
JP2025019782A Pending JP2025065408A (ja) 2016-12-14 2025-02-10 肺高血圧症および他の肺障害の処置のための方法および組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022197348A Pending JP2023036678A (ja) 2016-12-14 2022-12-09 肺高血圧症および他の肺障害の処置のための方法および組成物
JP2025019782A Pending JP2025065408A (ja) 2016-12-14 2025-02-10 肺高血圧症および他の肺障害の処置のための方法および組成物

Country Status (10)

Country Link
US (5) US10912778B2 (https=)
EP (2) EP4620525A3 (https=)
JP (3) JP2020502121A (https=)
CN (1) CN110381951A (https=)
AU (3) AU2017378409A1 (https=)
BR (1) BR112019012251A2 (https=)
CA (1) CA3046025A1 (https=)
MX (1) MX2019006938A (https=)
RU (1) RU2019121646A (https=)
WO (1) WO2018112258A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2938343B1 (en) 2012-12-21 2018-09-12 Mayo Foundation For Medical Education And Research Methods and materials for treating calcific aortic valve stenosis
US10898494B2 (en) 2016-05-05 2021-01-26 Liquidia Technologies, Inc. Dry powder treprostinil for the treatment of pulmonary hypertension
EP4620525A3 (en) 2016-12-14 2025-12-03 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders
WO2018132371A2 (en) * 2017-01-10 2018-07-19 United Therapeutics Corporation Methods and compositions for treating pulmonary hypertension
WO2020210707A1 (en) * 2019-04-10 2020-10-15 Mayo Foundation For Medical Education And Research Methods and materials for gender-dependent treatment of cardiovascular dysfunction
KR20220019027A (ko) * 2019-06-10 2022-02-15 레스피라 테라퓨틱스 인크. 담체-기반 제제 및 관련 방법
CN112569210B (zh) * 2019-09-27 2023-09-15 盈科瑞(天津)创新医药研究有限公司 一种吸入用马昔腾坦溶液及其制备方法
CN112773898A (zh) * 2019-11-11 2021-05-11 广州华真医药科技有限公司 磷酸二酯酶5抑制剂在制备抗纤维化疾病药物中的应用
CN110946826B (zh) * 2019-12-12 2022-02-22 烟台大学 一种利奥西呱口服制剂及其制备方法
JP7727652B2 (ja) 2020-03-31 2025-08-21 インヴォックス ベルジアム エヌヴイ 少なくとも2つの液体組成物のエアロゾル送達
US11013688B1 (en) * 2020-05-28 2021-05-25 Softhale Nv Methods of treatment of viral diseases
KR20230096998A (ko) * 2020-10-28 2023-06-30 인스메드 인코포레이티드 트레프로스티닐 전구약물의 건조 분말 조성물 및 이의 사용 방법
US20250000873A1 (en) 2021-09-10 2025-01-02 Justus-Liebig-Universitaet Giessen Inhaled iloprost for rescue treatment and treatment as needed in pulmonary hypertension
CN121843699A (zh) * 2023-05-31 2026-04-10 瑞必治公司 肺动脉高压治疗方法
CN116687888A (zh) * 2023-06-02 2023-09-05 苏州易合医药有限公司 伐地那非和达泊西汀复方干粉吸入制剂及其制备方法
CN121714543A (zh) * 2024-09-23 2026-03-24 上海欣药智能科技有限公司 一种可吸入的含可溶性鸟苷酸环化酶受体激动剂的药物组合物及其用途

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338235A (en) 1970-12-15 1973-11-21 May & Baker Ltd Azapurinones
GB1493685A (en) 1970-12-15 1977-11-30 May & Baker Ltd 8-azapurinones
US4883810A (en) 1976-08-17 1989-11-28 Burroughs Wellcome Co. Ethers
US4306075A (en) 1980-03-28 1981-12-15 The Upjohn Company Composition and process
JPS58124778A (ja) 1982-01-20 1983-07-25 Toray Ind Inc 5,6,7−トリノル−4,8−インタ−m−フエニレンPGI↓2誘導体
DE3417638A1 (de) 1984-05-10 1985-11-14 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur bestimmung geringer stoffmengen von arzneimitteln, von koerpereigenen oder anderen chemischen substanzen in biologischem material
US5250534A (en) 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
GB9514464D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Medicaments
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6441245B1 (en) 1997-10-24 2002-08-27 United Therapeutics Corporation Process for stereoselective synthesis of prostacyclin derivatives
US6362178B1 (en) 1997-11-12 2002-03-26 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
DE19834044A1 (de) 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
US6521212B1 (en) 1999-03-18 2003-02-18 United Therapeutics Corporation Method for treating peripheral vascular disease by administering benzindene prostaglandins by inhalation
US6943166B1 (en) 1999-04-30 2005-09-13 Lilly Icos Llc. Compositions comprising phosphodiesterase inhabitors for the treatment of sexual disfunction
EA004872B1 (ru) 1999-08-03 2004-08-26 ЛИЛЛИ АЙКОС эЛ-эЛ-Си β-КАРБОЛИНОВЫЕ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
US6821975B1 (en) 1999-08-03 2004-11-23 Lilly Icos Llc Beta-carboline drug products
EP1219609B1 (en) 1999-09-16 2007-04-04 Tanabe Seiyaku Co., Ltd. Aromatic nitrogenous six-membered ring compounds
NZ524572A (en) 2000-09-06 2004-08-27 Tanabe Seiyaku Co Oral compositions comprising phosphodiesterase inhibitors ( PDE inhibitor )and an acidic substance such as fumaric acid with improved drug efficacy due to decrease solubility in neutral and alkaline regions
WO2002079143A1 (en) 2001-03-28 2002-10-10 Pfizer Limited N-phenpropylcyclopentyl-substituted glutaramide derivatives as nep inhibitors for fsad
TWI316055B (https=) 2001-04-26 2009-10-21 Nippon Shinyaku Co Ltd
DE10220570A1 (de) 2002-05-08 2003-11-20 Bayer Ag Carbamat-substituierte Pyrazolopyridine
US20040077624A1 (en) 2002-05-23 2004-04-22 Pfizer Inc. Novel combination
CA2536293A1 (en) * 2003-08-22 2005-03-03 Boehringer Ingelheim Pharmaceuticals, Inc. Methods of treating copd and pulmonary hypertension
JP2008546786A (ja) 2005-06-23 2008-12-25 シェーリング コーポレイション Pde5インヒビターの迅速吸収性経口処方物
CA2641393C (en) 2006-02-03 2014-12-16 Scidose Llc Novel epoprostenol formulation and method of making thereof
CN101495122B (zh) 2006-05-15 2011-10-05 联合治疗公司 使用定量吸入器给予曲前列尼
KR20160048222A (ko) 2007-12-17 2016-05-03 유나이티드 세러퓨틱스 코오포레이션 레모둘린?의 활성 성분인 트레프로스티닐의 개선된 제조 방법
WO2009086470A2 (en) 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide - donating compounds and uses thereof
KR20230085944A (ko) 2008-03-18 2023-06-14 아레나 파마슈티칼스, 인크. 프로스타시클린 (pgi2) 수용체와 관련된 장애의 치료에 유용한 상기 수용체의 조절제
WO2009115235A1 (en) 2008-03-20 2009-09-24 Bayer Schering Pharma Aktiengesellschaft Pde inhibitors for the treatment of pulmonary hypertension
LT2315587T (lt) 2008-08-13 2018-01-10 Actelion Pharmaceuticals Ltd. Terapinės kompozicijos, turinčios macitentano
KR20170024165A (ko) 2009-06-26 2017-03-06 니뽄 신야쿠 가부시키가이샤 결정
WO2011030351A2 (en) 2009-09-03 2011-03-17 Rubicon Research Private Limited Taste - masked pharmaceutical compositions
EP2480526A1 (en) 2009-09-23 2012-08-01 Arena Pharmaceuticals, Inc. Crystalline forms and processes for the preparation of pgi2 receptor agonists
EP3108888B1 (en) * 2010-03-15 2020-02-12 United Therapeutics Corporation Treatment for pulmonary hypertension
WO2011137734A1 (en) 2010-05-03 2011-11-10 Tsh Biopharm Company, Limited Pharmaceutical composition and method for treating hypertension
EP2593452B1 (en) 2010-07-14 2017-01-18 Novartis AG Ip receptor agonist heterocyclic compounds
EP2464346A1 (en) 2010-08-30 2012-06-20 Pulmatrix, Inc. Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder
US8561609B2 (en) 2010-12-07 2013-10-22 Respira Therapeutics, Inc. Dry powder inhaler
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
CN104853744B (zh) 2012-10-31 2018-01-19 维克多瑞有限责任公司 气溶胶化伊洛前列素的给药
US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
EP3110484A4 (en) 2014-02-21 2018-02-14 Respira Therapeutics, Inc. Powder inhaler, system and methods
EP3244968B1 (en) * 2015-01-13 2023-08-30 Vivus LLC Combination therapy for pulmonary hypertension
EP4620525A3 (en) 2016-12-14 2025-12-03 Respira Therapeutics, Inc. Methods and compositions for treatment of pulmonary hypertension and other lung disorders

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