JP2020502066A - キナーゼ阻害剤としての複素環式化合物 - Google Patents
キナーゼ阻害剤としての複素環式化合物 Download PDFInfo
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| KR20220102622A (ko) * | 2019-11-15 | 2022-07-20 | 우한 엘엘 사이언스 앤드 테크놀로지 디벨롭먼트 컴퍼니, 리미티드 | Rock 억제제 및 이의 제조 방법과 용도 |
| CN112979675B (zh) * | 2019-12-12 | 2023-12-19 | 维眸生物科技（上海）有限公司 | 一种小分子含硫杂环化合物 |
| KR102758256B1 (ko) * | 2019-12-31 | 2025-01-21 | 인더스트리얼 테크놀로지 리서치 인스티튜트 | β-아미노산 유도체, 키나아제 억제제 및 이를 함유하는 약학 조성물 |
| ES3015621T3 (en) * | 2019-12-31 | 2025-05-06 | Ind Tech Res Inst | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same |
| EP4192828A1 (en) * | 2020-08-04 | 2023-06-14 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| CN116438171A (zh) | 2020-09-16 | 2023-07-14 | 努拉生物公司 | 作为sarm1抑制剂的取代的吡啶衍生物 |
| MX2024001322A (es) | 2021-07-28 | 2024-04-30 | Nura Bio Inc | Derivados de piridina sustituida como inhibidores de sarm1. |
| CR20250520A (es) * | 2023-05-09 | 2025-12-19 | Amgen Inc | Alcoholes y éteres bicíclicos 5,6-condensados y 6,6-condensados y composiciones para su uso como moduladores de la 15-prostaglandina deshidrogenasa |
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| GB0218625D0 (en) * | 2002-08-10 | 2002-09-18 | Astex Technology Ltd | Pharmaceutical compounds |
| US20050090529A1 (en) | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| EP2044061A2 (en) * | 2006-07-20 | 2009-04-08 | Mehmet Kahraman | Benzothiophene inhibitors of rho kinase |
| CA2709883A1 (en) | 2007-12-19 | 2009-06-25 | The Scripps Research Institute | Benzimidazoles and analogs as rho kinase inhibitors |
| US20100093714A1 (en) * | 2008-10-13 | 2010-04-15 | Devraj Chakravarty | AMIDES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS |
| US20130129677A1 (en) | 2009-02-27 | 2013-05-23 | Siga Technologies, Inc. | Thienopyridine Derivatives for the Treatment and Prevention of Dengue Virus Infections |
| WO2011130740A2 (en) * | 2010-04-16 | 2011-10-20 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pyridylthiazole-based ureas as inhibitors of rho associated protein kinase (rock) and methods of use |
| US8697911B2 (en) | 2010-07-07 | 2014-04-15 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| AU2011329233A1 (en) * | 2010-11-15 | 2013-05-23 | Abbvie Deutschland Gmbh & Co Kg | NAMPT and ROCK inhibitors |
| WO2012139930A1 (en) * | 2011-04-11 | 2012-10-18 | Nerviano Medical Sciences S.R.L. | Pyrazolyl-pyrimidine derivatives as kinase inhibitors |
| HK1248070A1 (zh) * | 2015-05-18 | 2018-10-12 | 转化药物开发有限责任公司 | 作为激酶抑制剂的杂环化合物 |
-
2017
- 2017-11-20 US US16/462,213 patent/US10807966B2/en not_active Expired - Fee Related
- 2017-11-20 EP EP17872851.5A patent/EP3541806A4/en not_active Withdrawn
- 2017-11-20 JP JP2019527417A patent/JP2020502066A/ja not_active Withdrawn
- 2017-11-20 WO PCT/US2017/062643 patent/WO2018094362A1/en not_active Ceased
- 2017-11-20 CN CN201780084129.7A patent/CN110382481A/zh active Pending
- 2017-11-20 CA CA3082254A patent/CA3082254A1/en not_active Abandoned
- 2017-11-20 AU AU2017362571A patent/AU2017362571A1/en not_active Abandoned
-
2019
- 2019-05-21 IL IL266789A patent/IL266789A/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023543740A (ja) * | 2020-09-23 | 2023-10-18 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | キナーゼ阻害剤としてのピラゾリル－ピリミジン誘導体 |
| JP7839785B2 (ja) | 2020-09-23 | 2026-04-02 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | キナーゼ阻害剤としてのピラゾリル－ピリミジン誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3541806A4 (en) | 2020-07-01 |
| US20190284157A1 (en) | 2019-09-19 |
| CA3082254A1 (en) | 2018-05-24 |
| AU2017362571A1 (en) | 2019-07-11 |
| CN110382481A (zh) | 2019-10-25 |
| US10807966B2 (en) | 2020-10-20 |
| EP3541806A1 (en) | 2019-09-25 |
| WO2018094362A1 (en) | 2018-05-24 |
| IL266789A (en) | 2019-07-31 |
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