JP2020500847A5 - - Google Patents
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- JP2020500847A5 JP2020500847A5 JP2019525727A JP2019525727A JP2020500847A5 JP 2020500847 A5 JP2020500847 A5 JP 2020500847A5 JP 2019525727 A JP2019525727 A JP 2019525727A JP 2019525727 A JP2019525727 A JP 2019525727A JP 2020500847 A5 JP2020500847 A5 JP 2020500847A5
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- 241000725619 Dengue virus Species 0.000 claims 5
- -1 butyropillin Proteins 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 239000004055 small Interfering RNA Substances 0.000 claims 4
- 108091008036 Immune checkpoint proteins Proteins 0.000 claims 3
- 102000037982 Immune checkpoint proteins Human genes 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 241000710829 Dengue virus group Species 0.000 claims 2
- 101001019455 Homo sapiens ICOS ligand Proteins 0.000 claims 2
- 102100034980 ICOS ligand Human genes 0.000 claims 2
- 108700011259 MicroRNAs Proteins 0.000 claims 2
- 108091027967 Small hairpin RNA Proteins 0.000 claims 2
- 108020004459 Small interfering RNA Proteins 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 210000004443 dendritic cell Anatomy 0.000 claims 2
- 230000002452 interceptive effect Effects 0.000 claims 2
- 239000002679 microRNA Substances 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102100022464 5'-nucleotidase Human genes 0.000 claims 1
- 101150051188 Adora2a gene Proteins 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 102100029822 B- and T-lymphocyte attenuator Human genes 0.000 claims 1
- 102100024263 CD160 antigen Human genes 0.000 claims 1
- 102100038077 CD226 antigen Human genes 0.000 claims 1
- 102100027207 CD27 antigen Human genes 0.000 claims 1
- 102100038078 CD276 antigen Human genes 0.000 claims 1
- 101150013553 CD40 gene Proteins 0.000 claims 1
- 102100036008 CD48 antigen Human genes 0.000 claims 1
- 108010062802 CD66 antigens Proteins 0.000 claims 1
- 102100025221 CD70 antigen Human genes 0.000 claims 1
- 108010021064 CTLA-4 Antigen Proteins 0.000 claims 1
- 229940045513 CTLA4 antagonist Drugs 0.000 claims 1
- 101100463133 Caenorhabditis elegans pdl-1 gene Proteins 0.000 claims 1
- 102100024533 Carcinoembryonic antigen-related cell adhesion molecule 1 Human genes 0.000 claims 1
- 102100021396 Cell surface glycoprotein CD200 receptor 1 Human genes 0.000 claims 1
- 102100039498 Cytotoxic T-lymphocyte protein 4 Human genes 0.000 claims 1
- 102100025012 Dipeptidyl peptidase 4 Human genes 0.000 claims 1
- 102100029722 Ectonucleoside triphosphate diphosphohydrolase 1 Human genes 0.000 claims 1
- 102100031351 Galectin-9 Human genes 0.000 claims 1
- 101100229077 Gallus gallus GAL9 gene Proteins 0.000 claims 1
- 102100034459 Hepatitis A virus cellular receptor 1 Human genes 0.000 claims 1
- 102100034458 Hepatitis A virus cellular receptor 2 Human genes 0.000 claims 1
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 1
- 101000864344 Homo sapiens B- and T-lymphocyte attenuator Proteins 0.000 claims 1
- 101000761938 Homo sapiens CD160 antigen Proteins 0.000 claims 1
- 101000884298 Homo sapiens CD226 antigen Proteins 0.000 claims 1
- 101000914511 Homo sapiens CD27 antigen Proteins 0.000 claims 1
- 101000884279 Homo sapiens CD276 antigen Proteins 0.000 claims 1
- 101000716130 Homo sapiens CD48 antigen Proteins 0.000 claims 1
- 101000934356 Homo sapiens CD70 antigen Proteins 0.000 claims 1
- 101000969553 Homo sapiens Cell surface glycoprotein CD200 receptor 1 Proteins 0.000 claims 1
- 101000908391 Homo sapiens Dipeptidyl peptidase 4 Proteins 0.000 claims 1
- 101001012447 Homo sapiens Ectonucleoside triphosphate diphosphohydrolase 1 Proteins 0.000 claims 1
- 101001068136 Homo sapiens Hepatitis A virus cellular receptor 1 Proteins 0.000 claims 1
- 101001068133 Homo sapiens Hepatitis A virus cellular receptor 2 Proteins 0.000 claims 1
- 101001037256 Homo sapiens Indoleamine 2,3-dioxygenase 1 Proteins 0.000 claims 1
- 101001037261 Homo sapiens Indoleamine 2,3-dioxygenase 2 Proteins 0.000 claims 1
- 101001046687 Homo sapiens Integrin alpha-E Proteins 0.000 claims 1
- 101001055145 Homo sapiens Interleukin-2 receptor subunit beta Proteins 0.000 claims 1
- 101000971533 Homo sapiens Killer cell lectin-like receptor subfamily G member 1 Proteins 0.000 claims 1
- 101000984190 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily B member 1 Proteins 0.000 claims 1
- 101000984189 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily B member 2 Proteins 0.000 claims 1
- 101001138062 Homo sapiens Leukocyte-associated immunoglobulin-like receptor 1 Proteins 0.000 claims 1
- 101001137987 Homo sapiens Lymphocyte activation gene 3 protein Proteins 0.000 claims 1
- 101001018258 Homo sapiens Macrophage receptor MARCO Proteins 0.000 claims 1
- 101100460850 Homo sapiens NCR3LG1 gene Proteins 0.000 claims 1
- 101001109501 Homo sapiens NKG2-D type II integral membrane protein Proteins 0.000 claims 1
- 101000884270 Homo sapiens Natural killer cell receptor 2B4 Proteins 0.000 claims 1
- 101000831286 Homo sapiens Protein timeless homolog Proteins 0.000 claims 1
- 101000752245 Homo sapiens Rho guanine nucleotide exchange factor 5 Proteins 0.000 claims 1
- 101000669511 Homo sapiens T-cell immunoglobulin and mucin domain-containing protein 4 Proteins 0.000 claims 1
- 101000831007 Homo sapiens T-cell immunoreceptor with Ig and ITIM domains Proteins 0.000 claims 1
- 101000934346 Homo sapiens T-cell surface antigen CD2 Proteins 0.000 claims 1
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 1
- 101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 claims 1
- 101000764263 Homo sapiens Tumor necrosis factor ligand superfamily member 4 Proteins 0.000 claims 1
- 101000638251 Homo sapiens Tumor necrosis factor ligand superfamily member 9 Proteins 0.000 claims 1
- 101000801234 Homo sapiens Tumor necrosis factor receptor superfamily member 18 Proteins 0.000 claims 1
- 101000679903 Homo sapiens Tumor necrosis factor receptor superfamily member 25 Proteins 0.000 claims 1
- 101000851376 Homo sapiens Tumor necrosis factor receptor superfamily member 8 Proteins 0.000 claims 1
- 101000851370 Homo sapiens Tumor necrosis factor receptor superfamily member 9 Proteins 0.000 claims 1
- 101000863873 Homo sapiens Tyrosine-protein phosphatase non-receptor type substrate 1 Proteins 0.000 claims 1
- 101000955999 Homo sapiens V-set domain-containing T-cell activation inhibitor 1 Proteins 0.000 claims 1
- 101000666896 Homo sapiens V-type immunoglobulin domain-containing suppressor of T-cell activation Proteins 0.000 claims 1
- 102100040061 Indoleamine 2,3-dioxygenase 1 Human genes 0.000 claims 1
- 102100040062 Indoleamine 2,3-dioxygenase 2 Human genes 0.000 claims 1
- 102100022341 Integrin alpha-E Human genes 0.000 claims 1
- 102100026879 Interleukin-2 receptor subunit beta Human genes 0.000 claims 1
- 102000002698 KIR Receptors Human genes 0.000 claims 1
- 108010043610 KIR Receptors Proteins 0.000 claims 1
- 101150069255 KLRC1 gene Proteins 0.000 claims 1
- 102100021457 Killer cell lectin-like receptor subfamily G member 1 Human genes 0.000 claims 1
- 102000017578 LAG3 Human genes 0.000 claims 1
- 102100025584 Leukocyte immunoglobulin-like receptor subfamily B member 1 Human genes 0.000 claims 1
- 102100025583 Leukocyte immunoglobulin-like receptor subfamily B member 2 Human genes 0.000 claims 1
- 102100020943 Leukocyte-associated immunoglobulin-like receptor 1 Human genes 0.000 claims 1
- 101100404845 Macaca mulatta NKG2A gene Proteins 0.000 claims 1
- 102100033272 Macrophage receptor MARCO Human genes 0.000 claims 1
- 108010061593 Member 14 Tumor Necrosis Factor Receptors Proteins 0.000 claims 1
- 101000597780 Mus musculus Tumor necrosis factor ligand superfamily member 18 Proteins 0.000 claims 1
- 102100022682 NKG2-A/NKG2-B type II integral membrane protein Human genes 0.000 claims 1
- 102100022680 NKG2-D type II integral membrane protein Human genes 0.000 claims 1
- 102100029527 Natural cytotoxicity triggering receptor 3 ligand 1 Human genes 0.000 claims 1
- 101710089372 Programmed cell death protein 1 Proteins 0.000 claims 1
- 102100039367 T-cell immunoglobulin and mucin domain-containing protein 4 Human genes 0.000 claims 1
- 102100024834 T-cell immunoreceptor with Ig and ITIM domains Human genes 0.000 claims 1
- 102100025237 T-cell surface antigen CD2 Human genes 0.000 claims 1
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 1
- 102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 claims 1
- 108010065158 Tumor Necrosis Factor Ligand Superfamily Member 14 Proteins 0.000 claims 1
- 102100024586 Tumor necrosis factor ligand superfamily member 14 Human genes 0.000 claims 1
- 102100035283 Tumor necrosis factor ligand superfamily member 18 Human genes 0.000 claims 1
- 102100026890 Tumor necrosis factor ligand superfamily member 4 Human genes 0.000 claims 1
- 102100032101 Tumor necrosis factor ligand superfamily member 9 Human genes 0.000 claims 1
- 102100028785 Tumor necrosis factor receptor superfamily member 14 Human genes 0.000 claims 1
- 102100033728 Tumor necrosis factor receptor superfamily member 18 Human genes 0.000 claims 1
- 102100022203 Tumor necrosis factor receptor superfamily member 25 Human genes 0.000 claims 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 claims 1
- 102100036857 Tumor necrosis factor receptor superfamily member 8 Human genes 0.000 claims 1
- 102100036856 Tumor necrosis factor receptor superfamily member 9 Human genes 0.000 claims 1
- 102100029948 Tyrosine-protein phosphatase non-receptor type substrate 1 Human genes 0.000 claims 1
- 102100038929 V-set domain-containing T-cell activation inhibitor 1 Human genes 0.000 claims 1
- 102100038282 V-type immunoglobulin domain-containing suppressor of T-cell activation Human genes 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- IJJVMEJXYNJXOJ-UHFFFAOYSA-N fluquinconazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1N1C(=O)C2=CC(F)=CC=C2N=C1N1C=NC=N1 IJJVMEJXYNJXOJ-UHFFFAOYSA-N 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662423119P | 2016-11-16 | 2016-11-16 | |
| US62/423,119 | 2016-11-16 | ||
| PCT/US2017/061810 WO2018093907A1 (en) | 2016-11-16 | 2017-11-15 | Combination immunotherapies for treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020500847A JP2020500847A (ja) | 2020-01-16 |
| JP2020500847A5 true JP2020500847A5 (https=) | 2020-12-24 |
Family
ID=62146828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019525727A Pending JP2020500847A (ja) | 2016-11-16 | 2017-11-15 | 癌の処置のための併用免疫療法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10675304B2 (https=) |
| EP (1) | EP3541417A4 (https=) |
| JP (1) | JP2020500847A (https=) |
| CN (1) | CN110139671A (https=) |
| CA (1) | CA3082779A1 (https=) |
| WO (1) | WO2018093907A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9730989B2 (en) | 2015-07-02 | 2017-08-15 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for combination therapy with dengue virus and dendritic cells |
| CA2999881A1 (en) | 2015-09-26 | 2017-03-30 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for producing dendritic cells |
| JP2020500847A (ja) | 2016-11-16 | 2020-01-16 | プライムヴァックス イミュノ−オンコロジー，インク． | 癌の処置のための併用免疫療法 |
| EP3565567A4 (en) | 2017-01-04 | 2020-07-29 | Primevax Immuno-Oncology, Inc. | COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| EP3721899A1 (en) * | 2019-04-08 | 2020-10-14 | China Medical University | Combination therapies comprising dendritic cells-based vaccine and immune checkpoint inhibitor |
| CR20220220A (es) | 2019-11-18 | 2022-09-20 | Janssen Biotech Inc | Vacunas basadas en calr y jak2 mutantes y sus usos |
| CN110904229B (zh) * | 2019-11-25 | 2020-09-29 | 济南市中心医院 | Ilt4在肿瘤诊治中的应用 |
| CA3187944A1 (en) | 2020-06-22 | 2021-12-30 | Ngm Biopharmaceuticals, Inc. | Lair-1-binding agents and methods of use thereof |
| EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| CN116546999A (zh) * | 2020-09-27 | 2023-08-04 | 深圳华大生命科学研究院 | 药物组合物及其制备方法和应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1015972A (en) | 1905-09-25 | 1912-01-30 | Westinghouse Electric & Mfg Co | Electric switch. |
| US1035755A (en) | 1908-07-21 | 1912-08-13 | Glenn S Smith | Draftsman's apparatus. |
| US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
| AU2872199A (en) | 1998-02-20 | 1999-09-06 | Rockefeller University, The | Apoptotic cell-mediated antigen presentation to dendritic cells |
| US6048686A (en) | 1998-05-05 | 2000-04-11 | Randy Kyle Brown | Hyperthermia and immunotherapy for cancer |
| US6524587B1 (en) * | 1998-05-05 | 2003-02-25 | Bruce W. Lyday | Hyperthermia and immunotherapy for leukemias lymphomas, and solid tumors |
| WO2000057909A2 (en) | 1999-03-26 | 2000-10-05 | Walter Reed Army Institute Of Research | Attenuated dengue-2 virus vaccine |
| EP1165127B1 (en) * | 1999-03-26 | 2008-12-31 | Walter Reed Army Institute of Research | Multivalent dengue virus vaccine |
| EP1168924A4 (en) | 1999-03-31 | 2002-09-04 | Univ Pittsburgh | DERIVATIVED IMMUNOGENES IN VITRO INDUCTION OF ANTIQUE-SPECIFIC T-CELLS USING DENDRITIC CELL-TUMOR CELL OR DENDRITIC CELL-VIRAL CELL |
| EP1484064A1 (en) | 2003-06-04 | 2004-12-08 | Gesellschaft für Biotechnologische Forschung | Therapeutical composition containing dentritic cells and use thereof |
| WO2006001120A1 (ja) | 2004-06-24 | 2006-01-05 | Dnavec Research Inc. | マイナス鎖rnaウイルスを含む抗癌剤 |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| PL2589602T3 (pl) * | 2006-08-15 | 2016-11-30 | Rozwinięcie komponentów szczepionki przeciwko wirusowi dengi | |
| EP2714076A1 (en) | 2011-05-26 | 2014-04-09 | GlaxoSmithKline Biologicals S.A. | Inactivated dengue virus vaccine |
| JP2015513401A (ja) | 2012-03-02 | 2015-05-14 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | 樹状細胞ワクチンの調製方法 |
| US9879003B2 (en) | 2012-04-11 | 2018-01-30 | Dana-Farber Cancer Institute, Inc. | Host targeted inhibitors of dengue virus and other viruses |
| JP2015520196A (ja) | 2012-06-10 | 2015-07-16 | タケダ ワクチン, インコーポレイテッドTakeda Vaccines, Inc. | デングウイルスに対するワクチン投与のための組成物および方法 |
| EP3473708B1 (en) | 2012-07-24 | 2021-01-27 | The General Hospital Corporation | Oncolytic virus therapy for resistant tumors |
| ES2738582T3 (es) * | 2014-02-14 | 2020-01-23 | Immune Design Corp | Inmunoterapia del cáncer a través de combinación de inmunoestimulación local y sistémica |
| KR102873947B1 (ko) * | 2015-05-07 | 2025-10-22 | 베이롤 칼리지 오브 메드신 | 수지상 세포 면역요법 |
| US9730989B2 (en) * | 2015-07-02 | 2017-08-15 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for combination therapy with dengue virus and dendritic cells |
| CA2999881A1 (en) * | 2015-09-26 | 2017-03-30 | PrimeVax Immuno-Oncology, Inc. | Compositions and methods for producing dendritic cells |
| JP2020500847A (ja) | 2016-11-16 | 2020-01-16 | プライムヴァックス イミュノ−オンコロジー，インク． | 癌の処置のための併用免疫療法 |
| EP3565567A4 (en) | 2017-01-04 | 2020-07-29 | Primevax Immuno-Oncology, Inc. | COMPOSITIONS AND METHODS OF THERAPY WITH DENGUE VIRUS |
| SG11201912163WA (en) | 2017-06-15 | 2020-01-30 | Primevax Immuno Oncology Inc | Compositions and methods for cancer therapy with dengue virus and dendritic cells |
-
2017
- 2017-11-15 JP JP2019525727A patent/JP2020500847A/ja active Pending
- 2017-11-15 EP EP17871276.6A patent/EP3541417A4/en not_active Withdrawn
- 2017-11-15 CN CN201780076988.1A patent/CN110139671A/zh active Pending
- 2017-11-15 WO PCT/US2017/061810 patent/WO2018093907A1/en not_active Ceased
- 2017-11-15 CA CA3082779A patent/CA3082779A1/en active Pending
-
2019
- 2019-05-15 US US16/413,444 patent/US10675304B2/en active Active
-
2020
- 2020-05-14 US US15/931,787 patent/US11357795B2/en active Active
-
2022
- 2022-06-10 US US17/837,294 patent/US12377115B2/en active Active
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