JP2020203845A - 微粒子付着防止剤 - Google Patents
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract
Description
本発明の微粒子付着防止剤において、芍薬抽出物、当帰抽出物、カキ葉抽出物は、一般的な抽出方法により得ることができ、たとえばそれぞれを抽出溶媒と共に浸漬または加熱還流した後、濾過し、濃縮して得ることができる。
(付着防止効果の評価法)
試験は、人工皮革(小松マテーレ株式会社製)またはリント布(株式会社浪速製作所製)をプラスチック容器の蓋の内側に取り付けたものに、サンプルを塗布して乾燥させ、プラスチック容器には都市大気粉塵(国立環境研究所製、NIES No.28;以下、「大気粉塵」)を一定量入れて実施した。
1:付着率が20%未満、
2:付着率が20%以上50%未満、
3:付着率が50%以上80%未満、
4:付着率が80%以上。
1:7名以上が刺激性を感じなかった、
2:5名以上7名未満が刺激性を感じなかった、
3:5名未満が刺激を感じなかった。
<実施例1>
・芍薬抽出物:10質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:90質量%
<実施例2>
・芍薬抽出物:5質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:95質量%
<実施例3>
・芍薬抽出物:1質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:99質量%
<実施例4>
・当帰抽出物:10質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:90質量%
<実施例5>
・当帰抽出物:5質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:95質量%
<実施例6>
・当帰抽出物:1質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:99質量%
<実施例7>
・カキ葉抽出物:10質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:90質量%
<実施例8>
・カキ葉抽出物:5質量%
(抽出溶媒は水と1,3−ブチレングリコールとの1:1混合物)
・精製水:95質量%
<実施例9>
・ペオニフロリン:0.01質量%
・精製水:99.99質量%
<実施例10>
・ペオニフロリン:0.001質量%
・精製水:99.999質量%
<比較例1>
・精製水:100質量%
<比較例2>
・N−ヤシ油脂肪酸アシルL−アルギニンエチル・DL−ピロリドンカルボン酸塩:0.1質量%
・精製水:99.9質量%
<比較例3>
・N−ヤシ油脂肪酸アシルL−アルギニンエチル・DL−ピロリドンカルボン酸塩:1質量%
・精製水:99質量%
<比較例4>
・ラウリル硫酸ナトリウム:10質量%
・精製水:90質量%
<比較例5>
・1,3−ブチレングリコール:50質量%
・精製水:50質量%
実施例1〜6についての結果を表1、実施例7〜10についての結果を表2、比較例1〜5についての結果を表3にそれぞれ示す。
Claims (7)
- 芍薬の抽出物、当帰の抽出物、カキの葉の抽出物およびペオニフロリンからなる群から選ばれる少なくともいずれかを有効成分として含む、微粒子付着防止剤。
- 芍薬の抽出物を、0.05〜50%(w/w)の濃度で含有する、請求項1に記載の微粒子付着防止剤。
- 当帰の抽出物を、0.05〜50%(w/w)の濃度で含有する、請求項1に記載の微粒子付着防止剤。
- カキの葉の抽出物を、0.05〜50%(w/w)の濃度で含有する、請求項1に記載の微粒子付着防止剤。
- 抽出溶媒が水とアルコールとの混合物である、請求項2〜4のいずれか1項に記載の微粒子付着防止剤。
- アルコールが1,3−ブチレングリコールである、請求項5に記載の微粒子付着防止剤。
- ペオニフロリンを、0.000001〜0.1%(w/w)の濃度で含有する、請求項1に記載の微粒子付着防止剤。
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10194916A (ja) * | 1997-01-14 | 1998-07-28 | Noevir Co Ltd | 抗菌性低刺激化粧料 |
JP2006002147A (ja) * | 2004-05-18 | 2006-01-05 | Shiseido Co Ltd | 花粉吸着防止剤 |
JP2017066031A (ja) * | 2015-09-28 | 2017-04-06 | 常盤薬品工業株式会社 | 微細粒子吸着防止剤 |
JP2018150270A (ja) * | 2017-03-13 | 2018-09-27 | 一丸ファルコス株式会社 | αMSH(1−8)発現抑制剤 |
-
2019
- 2019-06-17 JP JP2019111988A patent/JP7427213B2/ja active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10194916A (ja) * | 1997-01-14 | 1998-07-28 | Noevir Co Ltd | 抗菌性低刺激化粧料 |
JP2006002147A (ja) * | 2004-05-18 | 2006-01-05 | Shiseido Co Ltd | 花粉吸着防止剤 |
JP2017066031A (ja) * | 2015-09-28 | 2017-04-06 | 常盤薬品工業株式会社 | 微細粒子吸着防止剤 |
JP2018150270A (ja) * | 2017-03-13 | 2018-09-27 | 一丸ファルコス株式会社 | αMSH(1−8)発現抑制剤 |
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