JP2020198798A - 反応処理容器 - Google Patents
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Abstract
Description
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Claims (21)
- 基板と、前記基板の主面に形成された溝状の流路と、を備える反応処理容器であって、
前記流路は、蛇行状流路と、前記蛇行状流路に隣接する制動流路と、を含み、
前記制動流路の断面積は、前記蛇行状流路の断面積よりも大きいことを特徴とする反応処理容器。 - 前記蛇行状流路の断面積をSrとし、前記制動流路の断面積をSbとしたとき、断面積比Sb/Srは、1<Sb/Sr≦1.8の範囲内であることを特徴とする請求項1に記載の反応処理容器。
- 前記断面積比Sb/Srは、1.02≦Sb/Sr≦1.5の範囲内であることを特徴とする請求項2に記載の反応処理容器。
- 前記断面積比Sb/Srは、1.02≦Sb/Sr≦1.2の範囲内であることを特徴とする請求項2に記載の反応処理容器。
- 前記蛇行状流路および前記制動流路は、開口部と、底面と、前記底面から前記開口部に向かって拡大するテーパ状の側面と、を備えることを特徴とする請求項1から4のいずれかに記載の反応処理容器。
- 前記蛇行状流路は、0.55mm〜0.95mmの開口幅、0mm〜0.95mmの底面幅、0.5mm〜0.9mmの深さ、および0°〜45°のテーパ角を有し、
前記制動流路は、0.65mm〜1.05mmの開口幅、0mm〜1.05mmの底面幅、0.5mm〜0.9mmの深さ、および0°〜45°のテーパ角を有することを特徴とする請求項5に記載の反応処理容器。 - 前記底面と前記側面の接続部が曲面状であることを特徴とする請求項5または6に記載の反応処理容器。
- 前記接続部の曲率半径は、0.2mm〜0.38mmであることを特徴とする請求項7に記載の反応処理容器。
- 前記蛇行状流路は、屈曲部を含み、
前記屈曲部の曲率半径は、0.3mm〜10mmであることを特徴とする請求項1から8のいずれかに記載の反応処理容器。 - 基板と、前記基板の主面に形成された溝状の流路と、を備える反応処理容器であって、
前記流路は、蛇行状流路と、前記流路内を流れる試料から蛍光を検出するために励起光の照射を受ける検出流路と、を含み、
前記検出流路の断面積は、前記蛇行状流路の断面積よりも大きいことを特徴とする反応処理容器。 - 前記蛇行状流路の断面積をSrとし、前記検出流路の断面積をSdとしたとき、断面積比Sd/Srは、1<Sd/Sr≦1.8の範囲内であることを特徴とする請求項10に記載の反応処理容器。
- 前記断面積比Sd/Srは、1.02≦Sd/Sr≦1.5の範囲内であることを特徴とする請求項11に記載の反応処理容器。
- 前記断面積比Sd/Srは、1.02≦Sd/Sr≦1.2の範囲内であることを特徴とする請求項11に記載の反応処理容器。
- 前記蛇行状流路および前記検出流路は、開口部と、底面と、前記底面から前記開口部に向かって拡大するテーパ状の側面と、を備えることを特徴とする請求項10から13のいずれかに記載の反応処理容器。
- 前記蛇行状流路は、0.55mm〜0.95mmの開口幅、0mm〜0.95mmの底面幅、0.5mm〜0.9mmの深さ、および0°〜45°のテーパ角を有し、
前記検出流路は、0.7mm〜1.2mmの開口幅、0.15mm〜1.2mmの底面幅、0.5mm〜1.2mmの深さ、および0°〜45°のテーパ角を有することを特徴とする請求項14に記載の反応処理容器。 - 前記検出流路における前記底面は、前記基板の主面と平行な平面に形成されることを特徴とする請求項14または15に記載の反応処理容器。
- 前記底面と前記側面の接続部は、角張った形状に形成されることを特徴とする請求項16に記載の反応処理容器。
- 基板と、前記基板の主面に形成された溝状の流路と、を備える反応処理容器であって、
前記流路は、蛇行状流路と、前記蛇行状流路に隣接する制動流路と、前記流路内を流れる試料から蛍光を検出するために励起光の照射を受ける検出流路と、を含み、
前記制動流路の断面積は、前記蛇行状流路の断面積よりも大きく、
前記検出流路の断面積は、前記蛇行状流路の断面積よりも大きいことを特徴とする反応処理容器。 - 基板と、前記基板の主面に形成された溝状の流路と、前記流路から分岐する分岐流路と、前記分岐流路に設けられた試料導入口と、を備える反応処理容器であって、
当該反応処理容器の使用の際にそれぞれ所定の温度に維持される複数の反応領域が前記基板に設定され、
前記複数の反応領域のうち前記分岐流路および前記試料導入口に最も近い反応領域と、前記分岐流路および前記試料導入口との間の距離が5mm以上であることを特徴とする反応処理容器。 - 基板と、前記基板の主面に形成された溝状の流路と、前記流路の両端に設けられた一対のフィルタと、前記流路から分岐する分岐流路と、前記分岐流路に設けられた試料導入口と、を備える反応処理容器であって、
前記試料導入口から前記試料導入口に最も近いフィルタに至るまでの流路の体積をVfとし、前記試料導入口から導入される試料の体積をVsとしたとき、k×Vs<Vf(kは0.1〜10の実数)を満たすことを特徴とする反応処理容器。 - 基板と、前記基板の主面に形成された溝状の流路と、前記流路の両端に設けられた一対のフィルタと、前記流路から分岐する分岐流路と、前記分岐流路に設けられた試料導入口と、を備える反応処理容器であって、
前記試料導入口から導入される試料の体積が1μL〜50μLであるとき、前記試料導入口から前記試料導入口に最も近いフィルタに至るまでの流路の長さが、2mm〜200mmであることを特徴とする反応処理容器。
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JP2019106911A JP6652673B1 (ja) | 2019-06-07 | 2019-06-07 | 反応処理容器 |
EP19872250.6A EP3766956A4 (en) | 2019-06-07 | 2019-09-05 | REACTION TREATMENT VESSELS AND REACTION TREATMENT PROCEDURES |
BR112020008899A BR112020008899A2 (pt) | 2019-06-07 | 2019-09-05 | Vaso de processamento de reação e método de processamento de reação |
SG10202101301YA SG10202101301YA (en) | 2019-06-07 | 2019-09-05 | Reaction processing vessel |
PCT/JP2019/034931 WO2020246051A1 (ja) | 2019-06-07 | 2019-09-05 | 反応処理容器および反応処理方法 |
RU2020122243A RU2752623C1 (ru) | 2019-06-07 | 2019-09-05 | Технологический реакционный сосуд |
SG11202005048XA SG11202005048XA (en) | 2019-06-07 | 2019-09-05 | Reaction processing vessel |
US16/856,147 US11465143B2 (en) | 2019-06-07 | 2020-04-23 | Reaction processing vessel |
SA520411995A SA520411995B1 (ar) | 2019-06-07 | 2020-05-18 | وعاء معالجة تفاعل |
CN202020868921.0U CN212610651U (zh) | 2019-06-07 | 2020-05-21 | 反应处理容器 |
CN202010435643.4A CN111500436B (zh) | 2019-06-07 | 2020-05-21 | 反应处理容器 |
ARP200101476A AR122271A1 (es) | 2019-06-07 | 2020-05-26 | Recipiente de procesamiento de reacción y método de procesamiento de reacción |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006054689A1 (ja) * | 2004-11-22 | 2006-05-26 | Nissui Pharmaceutical Co., Ltd. | マイクロチップ |
JP2014212705A (ja) * | 2013-04-23 | 2014-11-17 | 独立行政法人産業技術総合研究所 | マイクロ流体装置を活用した核酸増幅方法 |
WO2015019520A1 (ja) * | 2013-08-08 | 2015-02-12 | パナソニック株式会社 | マイクロ流体デバイス |
WO2015019626A1 (ja) * | 2013-08-08 | 2015-02-12 | パナソニック株式会社 | 核酸増幅デバイス、核酸増幅装置及び核酸増幅方法 |
WO2016021158A1 (ja) * | 2014-08-08 | 2016-02-11 | パナソニックIpマネジメント株式会社 | 核酸増幅デバイス |
WO2017094674A1 (ja) * | 2015-12-01 | 2017-06-08 | 日本板硝子株式会社 | Pcr反応容器、pcr装置およびpcr方法 |
JP2018019606A (ja) * | 2016-08-01 | 2018-02-08 | 日本板硝子株式会社 | 反応処理装置、反応処理方法および分注方法 |
JP2018141685A (ja) * | 2017-02-27 | 2018-09-13 | パナソニックIpマネジメント株式会社 | マイクロ流体デバイス及びマイクロ流体デバイスの製造方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3120466B2 (ja) | 1991-04-25 | 2000-12-25 | 株式会社日立製作所 | デオキシリボ核酸の増幅装置及び増幅方法 |
JP4721414B2 (ja) | 2005-08-15 | 2011-07-13 | キヤノン株式会社 | 反応カートリッジ、反応装置および反応カートリッジの溶液の移動方法 |
JP4685691B2 (ja) | 2006-04-13 | 2011-05-18 | 株式会社日立ソリューションズ | 検査チップ及び検査チップシステム |
JP5303983B2 (ja) | 2008-03-26 | 2013-10-02 | 株式会社島津製作所 | 反応処理方法及び反応処理装置 |
RU2385940C1 (ru) * | 2008-10-23 | 2010-04-10 | Общество с ограниченной ответственностью "ВИНТЕЛ" | Способ определения нуклеиновых кислот методом полимеразно-цепной реакции в режиме реального времени и устройство для его осуществления |
JP5297887B2 (ja) | 2009-05-19 | 2013-09-25 | 日本板硝子株式会社 | 蛍光分析用光分波検出器及び蛍光検出システム |
KR101368463B1 (ko) * | 2010-04-23 | 2014-03-03 | 나노바이오시스 주식회사 | 2개의 열 블록을 포함하는 pcr 장치 |
GB201010237D0 (en) * | 2010-06-18 | 2010-07-21 | Lgc Ltd | Methods and apparatuses |
RU2015102158A (ru) | 2012-06-26 | 2016-08-20 | Новартис Аг | 2-аминобензофеноновые уф-абсорберы для материалов офтальмологических линз |
WO2015019521A1 (ja) * | 2013-08-08 | 2015-02-12 | パナソニックIpマネジメント株式会社 | マイクロ流体デバイス |
KR101618113B1 (ko) * | 2014-02-10 | 2016-05-09 | 나노바이오시스 주식회사 | 일 방향 슬라이딩 구동 수단을 구비하는 pcr 장치 및 이를 이용하는 pcr 방법 |
JP6476621B2 (ja) | 2014-07-14 | 2019-03-06 | 株式会社ニデック | 眼内レンズ挿入器具 |
EP3536775A4 (en) * | 2016-11-01 | 2020-06-03 | Nippon Sheet Glass Company, Limited | REACTION TREATMENT CONTAINER AND REACTION TREATMENT DEVICE |
CN110785491A (zh) * | 2017-06-23 | 2020-02-11 | 日本板硝子株式会社 | 反应处理装置 |
-
2019
- 2019-06-07 JP JP2019106911A patent/JP6652673B1/ja active Active
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- 2020-05-21 CN CN202020868921.0U patent/CN212610651U/zh active Active
- 2020-05-26 AR ARP200101476A patent/AR122271A1/es unknown
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006054689A1 (ja) * | 2004-11-22 | 2006-05-26 | Nissui Pharmaceutical Co., Ltd. | マイクロチップ |
JP2014212705A (ja) * | 2013-04-23 | 2014-11-17 | 独立行政法人産業技術総合研究所 | マイクロ流体装置を活用した核酸増幅方法 |
WO2015019520A1 (ja) * | 2013-08-08 | 2015-02-12 | パナソニック株式会社 | マイクロ流体デバイス |
WO2015019626A1 (ja) * | 2013-08-08 | 2015-02-12 | パナソニック株式会社 | 核酸増幅デバイス、核酸増幅装置及び核酸増幅方法 |
WO2016021158A1 (ja) * | 2014-08-08 | 2016-02-11 | パナソニックIpマネジメント株式会社 | 核酸増幅デバイス |
WO2017094674A1 (ja) * | 2015-12-01 | 2017-06-08 | 日本板硝子株式会社 | Pcr反応容器、pcr装置およびpcr方法 |
JP2018019606A (ja) * | 2016-08-01 | 2018-02-08 | 日本板硝子株式会社 | 反応処理装置、反応処理方法および分注方法 |
JP2018141685A (ja) * | 2017-02-27 | 2018-09-13 | パナソニックIpマネジメント株式会社 | マイクロ流体デバイス及びマイクロ流体デバイスの製造方法 |
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CN212610651U (zh) | 2021-02-26 |
CN111500436A (zh) | 2020-08-07 |
AR122271A1 (es) | 2022-08-31 |
SG10202101301YA (en) | 2021-03-30 |
CN111500436B (zh) | 2023-11-21 |
SA520411995B1 (ar) | 2021-04-12 |
JP6652673B1 (ja) | 2020-02-26 |
WO2020246051A1 (ja) | 2020-12-10 |
EP3766956A4 (en) | 2021-07-21 |
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