JP2020002172A5 - - Google Patents
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- Publication number
- JP2020002172A5 JP2020002172A5 JP2019167098A JP2019167098A JP2020002172A5 JP 2020002172 A5 JP2020002172 A5 JP 2020002172A5 JP 2019167098 A JP2019167098 A JP 2019167098A JP 2019167098 A JP2019167098 A JP 2019167098A JP 2020002172 A5 JP2020002172 A5 JP 2020002172A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- monoclonal antibody
- seq
- administered
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010019233 Headaches Diseases 0.000 claims 6
- 231100000869 headache Toxicity 0.000 claims 6
- 239000013604 expression vector Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 229940127597 CGRP antagonist Drugs 0.000 claims 1
- 206010036313 Post-traumatic headache Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 239000003735 calcitonin gene related peptide receptor antagonist Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000009863 impact test Methods 0.000 claims 1
- 229940071643 prefilled syringe Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562232343P | 2015-09-24 | 2015-09-24 | |
| US62/232,343 | 2015-09-24 | ||
| US201662375825P | 2016-08-16 | 2016-08-16 | |
| US62/375,825 | 2016-08-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515658A Division JP2018532728A (ja) | 2015-09-24 | 2016-09-23 | （持続性）外傷後頭痛の予防、治療および低減 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020002172A JP2020002172A (ja) | 2020-01-09 |
| JP2020002172A5 true JP2020002172A5 (cg-RX-API-DMAC7.html) | 2020-09-10 |
Family
ID=57121460
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515658A Pending JP2018532728A (ja) | 2015-09-24 | 2016-09-23 | （持続性）外傷後頭痛の予防、治療および低減 |
| JP2019167098A Pending JP2020002172A (ja) | 2015-09-24 | 2019-09-13 | （持続性）外傷後頭痛の予防、治療および低減 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515658A Pending JP2018532728A (ja) | 2015-09-24 | 2016-09-23 | （持続性）外傷後頭痛の予防、治療および低減 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20170088612A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3353202B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2018532728A (cg-RX-API-DMAC7.html) |
| KR (2) | KR20180058777A (cg-RX-API-DMAC7.html) |
| CN (1) | CN108473560A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2016325738A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2999809A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201890578A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2846878T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1258385A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL258008A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2018003713A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017051385A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201604040PA (en) | 2011-05-20 | 2016-07-28 | Alderbio Holdings Llc | Anti-cgrp compositions and use thereof |
| JP6374789B2 (ja) | 2011-05-20 | 2018-08-15 | アルダーバイオ・ホールディングズ・エルエルシー | 羞明または光嫌悪症を予防または抑制する抗ｃｇｒｐ抗体および抗体断片のそれを必要とする対象、特に片頭痛患者における使用 |
| US20170114122A1 (en) | 2015-10-23 | 2017-04-27 | Alderbio Holdings Llc | Regulation of glucose metabolism using anti-cgrp antibodies |
| US12168004B2 (en) | 2014-02-05 | 2024-12-17 | Merck Sharp & Dohme Llc | Treatment of migraine |
| KR20220136460A (ko) | 2014-02-05 | 2022-10-07 | 머크 샤프 앤드 돔 엘엘씨 | Cgrp-활성 화합물에 대한 정제 제제 |
| HRP20240159T1 (hr) | 2014-03-21 | 2024-04-12 | Teva Pharmaceuticals International Gmbh | Antagonistička protutijela usmjerena protiv peptida povezanog s genom kalcitonina i postupci koji ih koriste |
| WO2018055574A1 (en) | 2016-09-23 | 2018-03-29 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
| US12398209B2 (en) * | 2018-01-22 | 2025-08-26 | Janssen Biotech, Inc. | Methods of treating cancers with antagonistic anti-PD-1 antibodies |
| US12383545B1 (en) | 2018-06-08 | 2025-08-12 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| US10899826B1 (en) | 2018-09-13 | 2021-01-26 | Teva Pharmaceuticals International Gmbh | Pharmaceutical compositions for an anti-CGRP antagonist antibody |
| JOP20210156A1 (ar) | 2019-01-08 | 2023-01-30 | H Lundbeck As | علاج إسعافي وعلاج سريع للصداع باستخدام أجسام مضادة لـ cgrp |
| AU2020259461A1 (en) * | 2019-04-18 | 2021-11-11 | Allergan Sales, Llc | CGRP antagonists for the treatment of medication overuse headache, post-traumatic headache, post-concussion syndrome and vertigo |
| AU2020202454A1 (en) | 2020-04-06 | 2021-10-21 | H. Lundbeck A/S | Treatment of most bothersome symptom (MBS) associated with migraine using anti-CGRP antibodies |
| JP2023528453A (ja) | 2020-06-03 | 2023-07-04 | ミオトックス，エルエルシー | 片頭痛障害を治療するためのゾーンおよび標的化方法および使用 |
| AU2021319090A1 (en) | 2020-07-29 | 2023-03-02 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| WO2022140537A1 (en) | 2020-12-22 | 2022-06-30 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| WO2023049920A1 (en) | 2021-09-27 | 2023-03-30 | Allergan Pharmaceuticals International Limited | Combination comprising atogepant for treating migraine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9704770D0 (sv) * | 1997-12-19 | 1997-12-19 | Astra Ab | New use |
| EP2380592B1 (en) * | 2005-11-14 | 2018-03-07 | Teva Pharmaceuticals International GmbH | Antagonist antibody directed against calcitonin gene-related peptide |
| SG10201604040PA (en) * | 2011-05-20 | 2016-07-28 | Alderbio Holdings Llc | Anti-cgrp compositions and use thereof |
| US9163243B2 (en) * | 2012-01-10 | 2015-10-20 | Noxxon Pharma Ag | Nucleic acids specifically binding CGRP |
| US8722060B2 (en) * | 2012-05-23 | 2014-05-13 | William J. Binder | Method of treating vertigo |
-
2016
- 2016-09-23 KR KR1020187011355A patent/KR20180058777A/ko not_active Ceased
- 2016-09-23 JP JP2018515658A patent/JP2018532728A/ja active Pending
- 2016-09-23 WO PCT/IB2016/055720 patent/WO2017051385A1/en not_active Ceased
- 2016-09-23 AU AU2016325738A patent/AU2016325738A1/en not_active Abandoned
- 2016-09-23 KR KR1020207008057A patent/KR20200035163A/ko not_active Withdrawn
- 2016-09-23 ES ES16778888T patent/ES2846878T3/es active Active
- 2016-09-23 EP EP16778888.4A patent/EP3353202B1/en active Active
- 2016-09-23 US US15/274,331 patent/US20170088612A1/en not_active Abandoned
- 2016-09-23 CA CA2999809A patent/CA2999809A1/en not_active Abandoned
- 2016-09-23 HK HK19100783.0A patent/HK1258385A1/zh unknown
- 2016-09-23 EA EA201890578A patent/EA201890578A1/ru unknown
- 2016-09-23 MX MX2018003713A patent/MX2018003713A/es unknown
- 2016-09-23 CN CN201680068514.8A patent/CN108473560A/zh active Pending
-
2018
- 2018-03-11 IL IL258008A patent/IL258008A/en unknown
-
2019
- 2019-06-11 US US16/437,776 patent/US20200148761A1/en not_active Abandoned
- 2019-09-13 JP JP2019167098A patent/JP2020002172A/ja active Pending
- 2019-11-06 AU AU2019261726A patent/AU2019261726A1/en not_active Abandoned
-
2021
- 2021-04-05 US US17/222,737 patent/US20220048986A1/en not_active Abandoned
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