JP2019535298A5 - - Google Patents
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- JP2019535298A5 JP2019535298A5 JP2019528542A JP2019528542A JP2019535298A5 JP 2019535298 A5 JP2019535298 A5 JP 2019535298A5 JP 2019528542 A JP2019528542 A JP 2019528542A JP 2019528542 A JP2019528542 A JP 2019528542A JP 2019535298 A5 JP2019535298 A5 JP 2019535298A5
- Authority
- JP
- Japan
- Prior art keywords
- aimr
- acid sequence
- aimp
- interest
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 17
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical group 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 238000010442 DNA editing Methods 0.000 claims 1
- 230000004568 DNA-binding Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 230000002222 downregulating effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662426669P | 2016-11-28 | 2016-11-28 | |
| US62/426,669 | 2016-11-28 | ||
| PCT/IL2017/051293 WO2018096547A1 (en) | 2016-11-28 | 2017-11-28 | Isolated polynucleotides and polypeptides and methods of using same for expressing an expression product of interest |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019535298A JP2019535298A (ja) | 2019-12-12 |
| JP2019535298A5 true JP2019535298A5 (https=) | 2021-01-07 |
Family
ID=60766018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019528542A Pending JP2019535298A (ja) | 2016-11-28 | 2017-11-28 | 単離ポリヌクレオチドおよびポリペプチドおよび関心のある発現産物を発現させるためにそれらを使用する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11542508B2 (https=) |
| EP (1) | EP3545095A1 (https=) |
| JP (1) | JP2019535298A (https=) |
| CN (1) | CN110234765A (https=) |
| WO (1) | WO2018096547A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110234765A (zh) | 2016-11-28 | 2019-09-13 | 耶达研究及发展有限公司 | 分离的多核苷酸和多肽及使用它们来表达感兴趣的表达产物的方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| DE122007000007I2 (de) | 1986-04-09 | 2010-12-30 | Genzyme Corp | Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| US5541110A (en) | 1994-05-17 | 1996-07-30 | Bristol-Myers Squibb | Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica |
| US6774279B2 (en) | 1997-05-30 | 2004-08-10 | Carnegie Institution Of Washington | Use of FLP recombinase in mice |
| WO2003080809A2 (en) | 2002-03-21 | 2003-10-02 | Sangamo Biosciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| EP2806025B1 (en) | 2002-09-05 | 2019-04-03 | California Institute of Technology | Use of zinc finger nucleases to stimulate gene targeting |
| US20060014264A1 (en) | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
| US20070190601A1 (en) | 2004-10-08 | 2007-08-16 | Avigenics, Inc. | Modified integrase and methods of use |
| EP2067402A1 (en) | 2007-12-07 | 2009-06-10 | Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; | Transponson-mediated mutagenesis in spermatogonial stem cells |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| CN109554350B (zh) | 2012-11-27 | 2022-09-23 | 儿童医疗中心有限公司 | 用于胎儿血红蛋白再诱导的靶向bcl11a远端调控元件 |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| WO2015033343A1 (en) | 2013-09-03 | 2015-03-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Compositions and methods for expressing recombinant polypeptides |
| CN110234765A (zh) | 2016-11-28 | 2019-09-13 | 耶达研究及发展有限公司 | 分离的多核苷酸和多肽及使用它们来表达感兴趣的表达产物的方法 |
-
2017
- 2017-11-28 CN CN201780084829.6A patent/CN110234765A/zh active Pending
- 2017-11-28 JP JP2019528542A patent/JP2019535298A/ja active Pending
- 2017-11-28 US US16/346,124 patent/US11542508B2/en active Active
- 2017-11-28 EP EP17817906.5A patent/EP3545095A1/en not_active Withdrawn
- 2017-11-28 WO PCT/IL2017/051293 patent/WO2018096547A1/en not_active Ceased
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