|
US4036840A
(en)
*
|
1972-06-07 |
1977-07-19 |
Icn Pharmaceuticals |
2-Substituted-s-triazolo[1,5a]pyrimidines
|
|
WO1993000313A2
(en)
|
1991-06-27 |
1993-01-07 |
Virginia Commonwealth University |
Sigma receptor ligands and the use thereof
|
|
TR200002182T2
(tr)
|
1998-01-27 |
2000-12-21 |
Aventis Pharmaceuticals Products Inc. |
İkame edilmiş aksozaherosayklil faktör xa inhibitörleri
|
|
US6194410B1
(en)
|
1998-03-11 |
2001-02-27 |
Hoffman-La Roche Inc. |
Pyrazolopyrimidine and pyrazolines and process for preparation thereof
|
|
US20040014744A1
(en)
|
2002-04-05 |
2004-01-22 |
Fortuna Haviv |
Substituted pyridines having antiangiogenic activity
|
|
MXPA05003471A
(es)
|
2002-10-03 |
2005-07-01 |
Vertex Pharma |
Derivados de piperazina y piperadina para el tratamiento de enfermedades neurologicas.
|
|
WO2004108136A1
(en)
|
2003-06-04 |
2004-12-16 |
Vernalis (Cambridge) Limited |
Triazolo `1 , 5-a!pyrimidines and their use in medicine
|
|
EP1781659B1
(en)
|
2003-07-16 |
2008-11-05 |
Janssen Pharmaceutica N.V. |
Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
|
|
CA2553160C
(en)
|
2003-12-29 |
2010-09-28 |
Banyu Pharmaceutical Co., Ltd. |
2-heteroaryl-substituted benzimidazole derivative
|
|
EP1807085B1
(en)
|
2004-09-20 |
2013-08-21 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
US7829712B2
(en)
|
2004-09-20 |
2010-11-09 |
Xenon Pharmaceuticals Inc. |
Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
|
|
ATE479687T1
(de)
|
2004-10-15 |
2010-09-15 |
Takeda Pharmaceutical |
Kinaseinhibitoren
|
|
AU2006205808A1
(en)
*
|
2005-01-14 |
2006-07-20 |
Janssen Pharmaceutica N.V. |
Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
|
|
US7507842B2
(en)
|
2005-08-12 |
2009-03-24 |
Radiorx, Inc. |
Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof
|
|
WO2007113136A1
(de)
|
2006-03-30 |
2007-10-11 |
Basf Aktiengesellschaft |
Verwendung von substituierten riazolopyrimidinen zur bekämpfung von phyto pathogenen schadpilzen
|
|
JP2007332061A
(ja)
|
2006-06-14 |
2007-12-27 |
Nippon Kayaku Co Ltd |
新規ピラゾロ[1,5−a]ピリミジン誘導体及びその用途
|
|
US8153803B2
(en)
|
2006-07-18 |
2012-04-10 |
The General Hospital Corporation |
Compositions and methods for modulating sirtuin activity
|
|
WO2008048914A1
(en)
|
2006-10-17 |
2008-04-24 |
Boehringer Ingelheim International Gmbh |
Polycyclic compounds which modulate the cb2 receptor
|
|
BRPI0815096A2
(pt)
*
|
2007-07-18 |
2015-07-14 |
Janssen Pharmaceutica Nv |
Sulfonamidas como moduladores de trpm8
|
|
US8138168B1
(en)
|
2007-09-26 |
2012-03-20 |
Takeda Pharmaceutical Company Limited |
Renin inhibitors
|
|
GB0719803D0
(en)
|
2007-10-10 |
2007-11-21 |
Cancer Rec Tech Ltd |
Therapeutic compounds and their use
|
|
CN101560212B
(zh)
*
|
2009-05-26 |
2011-03-16 |
华中师范大学 |
1,2,4-三唑并[1,5-a]嘧啶-2-乙基硫醚双取代衍生物的制备及其应用
|
|
EP2651405A2
(en)
|
2010-12-14 |
2013-10-23 |
Electrophoretics Limited |
Casein kinase 1 (ck1 ) inhibitors
|
|
KR101548443B1
(ko)
|
2011-02-23 |
2015-08-28 |
화이자 인코포레이티드 |
신경 장애의 치료를 위한 이미다조[5,1-f][1,2,4]트라이아진
|
|
BR112013033375B1
(pt)
|
2011-06-27 |
2022-05-10 |
Janssen Pharmaceutica N.V |
Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário
|
|
JP2014527981A
(ja)
|
2011-09-23 |
2014-10-23 |
アドヴィナス・セラピューティックス・リミテッド |
アミド化合物、組成物およびその用途
|
|
CN103183675A
(zh)
*
|
2011-12-27 |
2013-07-03 |
山东轩竹医药科技有限公司 |
磷酸二酯酶-4抑制剂
|
|
US9034882B2
(en)
|
2012-03-05 |
2015-05-19 |
Bristol-Myers Squibb Company |
Inhibitors of human immunodeficiency virus replication
|
|
EP2834243B1
(en)
|
2012-03-09 |
2018-04-25 |
Lexicon Pharmaceuticals, Inc. |
PYRAZOLO[1,5-a]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
|
|
US9193736B2
(en)
*
|
2013-06-11 |
2015-11-24 |
Janssen Pharmaceutica, Nv |
PDE 10a inhibitors for the treatment of type II diabetes
|
|
US9328095B2
(en)
*
|
2013-10-15 |
2016-05-03 |
Janssen Pharmaceutica Nv |
Heteroaryl linked quinolinyl modulators of RORgammat
|
|
EP3110794A1
(en)
|
2014-02-27 |
2017-01-04 |
Merck Patent GmbH |
Heterocyclic compounds as nav channel inhibitors and uses thereof
|
|
CN106255689B
(zh)
|
2014-03-19 |
2019-09-17 |
勃林格殷格翰国际有限公司 |
杂芳基syk抑制剂
|
|
DK3134413T3
(da)
*
|
2014-04-23 |
2019-10-14 |
Dart Neuroscience Cayman Ltd |
Substituerede [1,2,4]triazolo[1,5-a]pyrimidin-7-yl-forbindelser som pde2-inhibitorer
|
|
CN105566321B
(zh)
|
2014-10-29 |
2020-04-21 |
广东东阳光药业有限公司 |
杂芳化合物及其在药物中的应用
|
|
CN105753817A
(zh)
|
2015-01-01 |
2016-07-13 |
成都贝斯凯瑞生物科技有限公司 |
一类取代氮杂环衍生物及其应用
|
|
WO2016145614A1
(en)
|
2015-03-17 |
2016-09-22 |
Merck Sharp & Dohme Corp. |
Triazolyl pyrimidinone compounds as pde2 inhibitors
|
|
WO2017000277A1
(en)
|
2015-07-01 |
2017-01-05 |
Merck Sharp & Dohme Corp. |
Substituted triazolo bicycliccompounds as pde2 inhibitors
|
|
WO2017000276A1
(en)
|
2015-07-01 |
2017-01-05 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocyclic compounds as pde2 inhibitors
|
|
WO2017066705A1
(en)
|
2015-10-14 |
2017-04-20 |
Aquinnah Pharmaceuticals, Inc. |
Compounds, compositions and methods of use against stress granules
|
|
CN108349979B
(zh)
|
2015-11-02 |
2021-04-09 |
詹森药业有限公司 |
[1,2,4]三唑并[1,5-a]嘧啶-7-基化合物
|
|
WO2017157882A1
(en)
|
2016-03-14 |
2017-09-21 |
Université Catholique de Louvain |
Serine biosynthetic pathway inhibitors
|
|
CN109890824B
(zh)
|
2016-11-02 |
2022-05-24 |
詹森药业有限公司 |
作为pde2抑制剂的[1,2,4]三唑并[1,5-a]嘧啶化合物
|
|
MY193511A
(en)
|
2016-11-02 |
2022-10-17 |
Janssen Pharmaceutica Nv |
[1,2,4]triazolo[1,5-a]pyrimidine derivatives as pde2 inhibitors
|
|
EA039102B1
(ru)
|
2016-11-02 |
2021-12-03 |
Янссен Фармацевтика Нв |
Соединения [1,2,4]триазоло[1,5-a]пиримидина в качестве ингибиторов pde2
|
|
US20190359609A1
(en)
|
2016-12-16 |
2019-11-28 |
Janssen Pharmaceutica Nv |
Bicyclic oga inhibitor compounds
|