JP2019528074A5 - - Google Patents
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- Publication number
- JP2019528074A5 JP2019528074A5 JP2019510850A JP2019510850A JP2019528074A5 JP 2019528074 A5 JP2019528074 A5 JP 2019528074A5 JP 2019510850 A JP2019510850 A JP 2019510850A JP 2019510850 A JP2019510850 A JP 2019510850A JP 2019528074 A5 JP2019528074 A5 JP 2019528074A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody according
- heavy chain
- light chain
- vector
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 4
- 230000033115 angiogenesis Effects 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 150000007523 nucleic acids Chemical class 0.000 claims description 2
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- 108091033319 polynucleotide Proteins 0.000 claims description 2
- 102000040430 polynucleotide Human genes 0.000 claims description 2
- 239000002157 polynucleotide Substances 0.000 claims description 2
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021152836A JP7277531B2 (ja) | 2016-08-23 | 2021-09-21 | 抗ｖｅｇｆ－ａ抗体ならびにそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662378391P | 2016-08-23 | 2016-08-23 | |
| US62/378,391 | 2016-08-23 | ||
| PCT/EP2017/071106 WO2018037001A1 (en) | 2016-08-23 | 2017-08-22 | Anti-vegf-a antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021152836A Division JP7277531B2 (ja) | 2016-08-23 | 2021-09-21 | 抗ｖｅｇｆ－ａ抗体ならびにそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019528074A JP2019528074A (ja) | 2019-10-10 |
| JP2019528074A5 true JP2019528074A5 (enExample) | 2020-10-01 |
| JP6949106B2 JP6949106B2 (ja) | 2021-10-13 |
Family
ID=59677248
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510850A Active JP6949106B2 (ja) | 2016-08-23 | 2017-08-22 | 抗ｖｅｇｆ−ａ抗体ならびにそれらの使用 |
| JP2021152836A Active JP7277531B2 (ja) | 2016-08-23 | 2021-09-21 | 抗ｖｅｇｆ－ａ抗体ならびにそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021152836A Active JP7277531B2 (ja) | 2016-08-23 | 2021-09-21 | 抗ｖｅｇｆ－ａ抗体ならびにそれらの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10919958B2 (enExample) |
| EP (2) | EP3783022A3 (enExample) |
| JP (2) | JP6949106B2 (enExample) |
| KR (1) | KR102538827B1 (enExample) |
| CN (1) | CN109863172B (enExample) |
| AU (2) | AU2017315076B2 (enExample) |
| CA (1) | CA3034576A1 (enExample) |
| ES (1) | ES2836286T3 (enExample) |
| IL (1) | IL264961B2 (enExample) |
| WO (1) | WO2018037001A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7485273B2 (ja) * | 2020-06-25 | 2024-05-16 | 国立大学法人 鹿児島大学 | 抗ｖｅｇｆ－ａ抗体による癌に対する治療応答性を予測又は決定するための方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5981216A (en) | 1985-04-01 | 1999-11-09 | Alusuisse Holdings A.G. | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| CN1191276C (zh) * | 1997-04-07 | 2005-03-02 | 基因技术股份有限公司 | 人源化抗体和制备人源化抗体的方法 |
| BRPI9809387B8 (pt) * | 1997-04-07 | 2021-05-25 | Genentech Inc | anticorpo humanizado anti-fator de crescimento endotelial vascular humano e composição que o compreende |
| EP2119793A1 (en) | 2000-06-28 | 2009-11-18 | Glycofi, Inc. | Methods for producing modified glycoproteins |
| AU2007205935B2 (en) | 2006-01-17 | 2013-07-11 | Synthon Biopharmaceuticals B.V. | Compositions and methods for humanization and optimization of N-glycans in plants |
| CN102006885A (zh) * | 2006-10-20 | 2011-04-06 | 先灵公司 | 完全人源抗vegf抗体及其使用方法 |
| EP1995309A1 (en) | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
| EP2604279A1 (en) * | 2008-03-27 | 2013-06-19 | ZymoGenetics, Inc. | Compositions and methods for inhibiting PDGFRBETA and VEGF-A |
| WO2010124009A2 (en) * | 2009-04-21 | 2010-10-28 | Schering Corporation | Fully human anti-vegf antibodies and methods of using |
| CN102276722B (zh) * | 2011-01-14 | 2013-05-08 | 中国科学院北京基因组研究所 | 新型血管内皮生长因子人源化单克隆抗体 |
| US9527925B2 (en) * | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| WO2013070565A1 (en) * | 2011-11-07 | 2013-05-16 | Medimmune, Llc | Multispecific and multivalent binding proteins and uses thereof |
-
2017
- 2017-08-22 IL IL264961A patent/IL264961B2/en unknown
- 2017-08-22 JP JP2019510850A patent/JP6949106B2/ja active Active
- 2017-08-22 EP EP20189960.6A patent/EP3783022A3/en active Pending
- 2017-08-22 ES ES17754722T patent/ES2836286T3/es active Active
- 2017-08-22 US US16/327,362 patent/US10919958B2/en active Active
- 2017-08-22 CA CA3034576A patent/CA3034576A1/en active Pending
- 2017-08-22 WO PCT/EP2017/071106 patent/WO2018037001A1/en not_active Ceased
- 2017-08-22 CN CN201780064561.XA patent/CN109863172B/zh active Active
- 2017-08-22 KR KR1020197007757A patent/KR102538827B1/ko active Active
- 2017-08-22 EP EP17754722.1A patent/EP3504236B1/en active Active
- 2017-08-22 AU AU2017315076A patent/AU2017315076B2/en active Active
-
2020
- 2020-12-18 AU AU2020289850A patent/AU2020289850B2/en active Active
-
2021
- 2021-01-19 US US17/152,409 patent/US11634483B2/en active Active
- 2021-09-21 JP JP2021152836A patent/JP7277531B2/ja active Active
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