JP2019526580A - 抗レトロウイルス処置を受けている対象においてヒト免疫不全ウイルス感染に対する免疫応答を誘発するための方法 - Google Patents
抗レトロウイルス処置を受けている対象においてヒト免疫不全ウイルス感染に対する免疫応答を誘発するための方法 Download PDFInfo
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- JP2019526580A JP2019526580A JP2019512191A JP2019512191A JP2019526580A JP 2019526580 A JP2019526580 A JP 2019526580A JP 2019512191 A JP2019512191 A JP 2019512191A JP 2019512191 A JP2019512191 A JP 2019512191A JP 2019526580 A JP2019526580 A JP 2019526580A
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16171—Demonstrated in vivo effect
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16271—Demonstrated in vivo effect
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
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- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662383140P | 2016-09-02 | 2016-09-02 | |
| US62/383,140 | 2016-09-02 | ||
| PCT/US2017/049817 WO2018045267A1 (en) | 2016-09-02 | 2017-09-01 | Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019526580A true JP2019526580A (ja) | 2019-09-19 |
| JP2019526580A5 JP2019526580A5 (cg-RX-API-DMAC7.html) | 2020-10-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019512191A Pending JP2019526580A (ja) | 2016-09-02 | 2017-09-01 | 抗レトロウイルス処置を受けている対象においてヒト免疫不全ウイルス感染に対する免疫応答を誘発するための方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10307477B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3506937A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2019526580A (cg-RX-API-DMAC7.html) |
| CN (1) | CN110494159A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017318689A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3035759A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018045267A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201901899B (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3197489T (lt) * | 2014-09-26 | 2021-07-26 | Beth Israel Deaconess Medical Center, Inc. | Būdai ir kompozicijos, skirti indukuoti apsauginį imunitetą prieš žmogaus imunodeficito viruso infekciją |
| RS62360B1 (sr) | 2015-12-15 | 2021-10-29 | Janssen Vaccines & Prevention Bv | Antigeni, vektori i sastavi virusa humane imunodeficijencije, i postupci njihove primene |
| EP3471765B1 (en) | 2016-06-16 | 2024-04-24 | Janssen Vaccines & Prevention B.V. | Hiv vaccine formulation |
| US10307477B2 (en) | 2016-09-02 | 2019-06-04 | Janssen Vaccines & Prevention B.V. | Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment |
| MX2019002938A (es) | 2016-09-15 | 2019-10-15 | Janssen Vaccines & Prevention Bv | Mutaciones estebilizantes de trimeros de proteinas de la envoltura del vih. |
| ES2976495T3 (es) | 2017-06-15 | 2024-08-02 | Janssen Vaccines & Prevention Bv | Vectores poxvirus que codifican antígenos del VIH y métodos de uso de los mismos |
| JP7253529B2 (ja) | 2017-07-19 | 2023-04-06 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 三量体安定化hivエンベロープタンパク質変異 |
| WO2019055888A1 (en) * | 2017-09-18 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHODS OF INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDER ANTIRETROVIRAL TREATMENT |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| WO2020237052A1 (en) * | 2019-05-22 | 2020-11-26 | Janssen Vaccines & Prevention B.V. | Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment |
| AU2020279988A1 (en) * | 2019-05-22 | 2021-12-23 | Aelix Therapeutics, S.L. | Dosage regimens for vaccines |
| MX2022005980A (es) | 2019-11-18 | 2022-09-07 | Janssen Biotech Inc | Vacunas basadas en calr y jak2 mutantes y sus usos. |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク,インコーポレーテツド | Psma及びsteap1ワクチン並びにそれらの使用 |
| EP4175721A1 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20230035403A1 (en) | 2020-07-06 | 2023-02-02 | Janssen Biotech, Inc. | Method For Determining Responsiveness To Prostate Cancer Treatment |
| US12295997B2 (en) | 2020-07-06 | 2025-05-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20220118081A1 (en) | 2020-10-20 | 2022-04-21 | Janssen Vaccines & Prevention B.V. | HIV vaccine regimens |
| US20230000973A1 (en) * | 2021-06-25 | 2023-01-05 | Janssen Vaccines & Prevention B.V. | Combinations of Vaccines and Neutralizing Antibodies for Treating Human Immunodeficiency Virus Infection in Subjects Undergoing Antiretroviral Treatment |
| WO2023198815A1 (en) | 2022-04-14 | 2023-10-19 | Janssen Vaccines & Prevention B.V. | Sequential administration of adenoviruses |
| WO2024036217A2 (en) * | 2022-08-09 | 2024-02-15 | Fred Hutchinson Cancer Center | Immunization strategies to more naturally guide the maturation of antibodies against human immunodeficiency virus (hiv) in hiv-infected subjects |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016049287A1 (en) * | 2014-09-26 | 2016-03-31 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for inducing protective immunity against human immunodeficiency virus infection |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| CA1341245C (en) | 1988-01-12 | 2001-06-05 | F. Hoffmann-La Roche Ag | Recombinant vaccinia virus mva |
| US5298416A (en) | 1989-01-18 | 1994-03-29 | British Technology Group Ltd. | Attenuated polioviruses |
| US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
| UA68327C2 (en) | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| US6479258B1 (en) | 1995-12-07 | 2002-11-12 | Diversa Corporation | Non-stochastic generation of genetic vaccines |
| GB0023203D0 (en) | 2000-09-21 | 2000-11-01 | Isis Innovation | Vaccination method |
| US6710173B1 (en) | 1999-06-25 | 2004-03-23 | Progenics Pharmaceuticals, Inc. | Stabilized viral envelope proteins and uses thereof |
| WO2001019958A2 (en) | 1999-09-17 | 2001-03-22 | Dana-Farber Cancer Institute, Inc. | Stabilized soluble glycoprotein trimers |
| PT1335987E (pt) | 2000-11-23 | 2006-05-31 | Bavarian Nordic As | Variante do virus vacina modificado ancara |
| JP4500049B2 (ja) | 2001-12-04 | 2010-07-14 | バヴァリアン・ノルディック・アクティーゼルスカブ | フラビウイルスns1サブユニットワクチン |
| BR0308783A (pt) | 2002-04-25 | 2005-01-04 | Crucell Holland Bv | Vetor de adenovìrus recombinante, método para produzir um vetor de adenovìrus recombinante, composição farmacêutica, método para tratar um corpo humano, e, kit de partes |
| AU2003291402A1 (en) | 2002-11-07 | 2004-06-03 | Beth Israel Deaconess Medical Center | MIP-1Alpha AND GM-CSF AS ADJUVANTS OF IMMUNE RESPONSE |
| WO2004050856A2 (en) | 2002-12-03 | 2004-06-17 | University Of Massachusetts | Polyvalent, primary hiv-1 glycoprotein dna vaccines and vaccination methods |
| EP2371380A1 (en) | 2003-03-28 | 2011-10-05 | The Government of the United States of America, represented by The Secretary, Department of Health and Human Services | MVA expressing modified hiv envelope, gag, and pol genes |
| WO2005027840A2 (en) | 2003-09-15 | 2005-03-31 | Chiron Corporation | Combination approaches for generating immune responses |
| WO2005052119A2 (en) | 2003-11-19 | 2005-06-09 | Beth Israel Deaconess Medical Center | Adjuvants of immune response |
| WO2006002079A2 (en) | 2004-06-15 | 2006-01-05 | Progenics Pharmaceuticals, Inc. | Hiv-1 neutralizing antibodies elicited by trimeric hiv-1 envelope glycoprotein complex |
| CA2573702C (en) | 2004-07-16 | 2013-10-15 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services | Vaccine constructs and combination of vaccines designed to improve the breadth of the immune response to diverse strains and clades of hiv |
| BRPI0516048A (pt) | 2004-10-13 | 2008-08-19 | Crucell Holland B V E Beth Isr | batelada de um adenovìrus recombinante defectivo em replicação baseado em um sorotipo do subgrupo c |
| US20100221241A1 (en) | 2005-07-06 | 2010-09-02 | University Of Maryland Biotechnology Institute | Constrained hiv envelope-based immunogen that simultaneously presents receptor and coreceptor binding sites |
| US8119140B2 (en) | 2005-08-23 | 2012-02-21 | Los Alamos Security, LLC | Immunogenic compositions comprising human immunodeficiency virus (HIV) mosaic Nef proteins |
| US20100143302A1 (en) | 2006-03-16 | 2010-06-10 | Crucell Holland B.V. | Recombinant Adenoviruses Based on Serotype 26 and 48, and Use Thereof |
| EP2040747A4 (en) | 2006-06-19 | 2010-08-25 | Progenics Pharm Inc | SOLUBLE STABILIZED TRIMERS HIV CREAM PROTEINS AND ITS USE |
| WO2008063331A2 (en) | 2006-10-23 | 2008-05-29 | Progenics Pharmaceuticals, Inc. | Modified gp140 envelope polypeptides of hiv-1 isolates, compositions, stabilized trimeric complexes, and uses thereof |
| US20080279879A1 (en) | 2006-11-17 | 2008-11-13 | New York University | INDUCTION OF BROADLY REACTIVE NEUTRALIZING ANTIBODIES BY FOCUSING THE IMMUNE RESPONSE ON V3 EPITOPES OF THE HIV-1 gp120 ENVELOPE |
| MX2009009342A (es) | 2007-03-02 | 2009-09-11 | Glaxosmithkline Biolog Sa | Metodo novedoso y composiciones. |
| SMT202000101T1 (it) | 2008-10-10 | 2020-03-13 | Childrens Medical Center | Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente |
| PT2358757T (pt) | 2008-11-18 | 2018-12-04 | Beth Israel Deaconess Medical Ct Inc | Vacinas antivirais com imunogenicidade celular melhorada |
| WO2010096561A1 (en) | 2009-02-18 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthetic hiv/siv gag proteins and uses thereof |
| CN105399833B (zh) | 2010-01-04 | 2019-09-06 | Kj 生物科学有限公司 | 用于疫苗和诊断学的Dps融合蛋白 |
| EP2529010B1 (en) | 2010-01-28 | 2017-04-19 | Bavarian Nordic A/S | Vaccinia virus mutants containing the major genomic deletions of mva |
| EP4226935A3 (en) | 2010-08-31 | 2023-09-06 | Theraclone Sciences, Inc. | Human immunodeficiency virus (hiv)-neutralizing antibodies |
| WO2013036791A2 (en) | 2011-09-09 | 2013-03-14 | Beth Israel Deaconess Medical Center, Inc. | Modified adenoviral vectors and methods of treatment using same |
| AU2012216792A1 (en) | 2011-09-12 | 2013-03-28 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies |
| WO2013055908A1 (en) | 2011-10-12 | 2013-04-18 | The Scripps Research Institute | An hiv-1 gp120 mini v3 loop and uses thereof |
| WO2014047261A1 (en) | 2012-09-19 | 2014-03-27 | Beth Israel Deaconess Medical Center, Inc. | Viruses associated with immunodeficiency and enteropathy and methods using same |
| SG11201503864TA (en) | 2012-11-16 | 2015-06-29 | Beth Israel Hospital | Recombinant adenoviruses and use thereof |
| MY187152A (en) | 2013-01-07 | 2021-09-06 | Beth Israel Deaconess Medical Ct Inc | Stabilized human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using same |
| WO2014124301A1 (en) | 2013-02-07 | 2014-08-14 | University Of Washington Through Its Center For Commercialization | Self-assembling protein nanostructures |
| US10376583B2 (en) | 2013-09-30 | 2019-08-13 | Beth Israel Deaconess Medical Center, Inc. | Human immunodeficiency virus therapies utilizing N332-glycan-dependent antibodies and a reservoir activator |
| JP2017507672A (ja) * | 2014-02-28 | 2017-03-23 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 複製型組み換えアデノウイルスベクター、組成物およびこれらの使用方法 |
| US10400015B2 (en) | 2014-09-04 | 2019-09-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant HIV-1 envelope proteins and their use |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| RS62360B1 (sr) | 2015-12-15 | 2021-10-29 | Janssen Vaccines & Prevention Bv | Antigeni, vektori i sastavi virusa humane imunodeficijencije, i postupci njihove primene |
| EP3471765B1 (en) | 2016-06-16 | 2024-04-24 | Janssen Vaccines & Prevention B.V. | Hiv vaccine formulation |
| US10307477B2 (en) | 2016-09-02 | 2019-06-04 | Janssen Vaccines & Prevention B.V. | Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment |
| MX2019002938A (es) | 2016-09-15 | 2019-10-15 | Janssen Vaccines & Prevention Bv | Mutaciones estebilizantes de trimeros de proteinas de la envoltura del vih. |
-
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016049287A1 (en) * | 2014-09-26 | 2016-03-31 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for inducing protective immunity against human immunodeficiency virus infection |
Non-Patent Citations (2)
| Title |
|---|
| LANCET HIV, vol. 2, JPN6020038435, 2015, pages 82 - 91, ISSN: 0004635836 * |
| PLOS ONE, vol. Vol.11, No.8: e0160341, JPN6020038438, August 2016 (2016-08-01), pages 1 - 17, ISSN: 0004635837 * |
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