JP2019524888A - 血液がんの治療のためのＰＰＡＲγアゴニスト - Google Patents

血液がんの治療のためのＰＰＡＲγアゴニスト Download PDF

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JP2019524888A
JP2019524888A JP2019530367A JP2019530367A JP2019524888A JP 2019524888 A JP2019524888 A JP 2019524888A JP 2019530367 A JP2019530367 A JP 2019530367A JP 2019530367 A JP2019530367 A JP 2019530367A JP 2019524888 A JP2019524888 A JP 2019524888A
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leukemia
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effective amount
therapeutically effective
milligrams
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JP2019524888A5 (https=
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クリストス マントゾロス
クリストス マントゾロス
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インテクリン セラピューティクス インコーポレイテッド
インテクリン セラピューティクス インコーポレイテッド
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Publication of JP2019524888A publication Critical patent/JP2019524888A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019530367A 2016-08-18 2017-08-18 血液がんの治療のためのＰＰＡＲγアゴニスト Pending JP2019524888A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022091309A JP2022116304A (ja) 2016-08-18 2022-06-06 血液がんの治療のためのＰＰＡＲγアゴニスト

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662376749P 2016-08-18 2016-08-18
US62/376,749 2016-08-18
PCT/US2017/047578 WO2018035446A1 (en) 2016-08-18 2017-08-18 PPARγ AGONIST FOR TREATMENT OF BLOOD CANCERS

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JP2022091309A Division JP2022116304A (ja) 2016-08-18 2022-06-06 血液がんの治療のためのＰＰＡＲγアゴニスト

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JP2019524888A true JP2019524888A (ja) 2019-09-05
JP2019524888A5 JP2019524888A5 (https=) 2020-10-01

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JP2019530367A Pending JP2019524888A (ja) 2016-08-18 2017-08-18 血液がんの治療のためのＰＰＡＲγアゴニスト
JP2022091309A Withdrawn JP2022116304A (ja) 2016-08-18 2022-06-06 血液がんの治療のためのＰＰＡＲγアゴニスト

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US (1) US20210379049A1 (https=)
EP (1) EP3500268A4 (https=)
JP (2) JP2019524888A (https=)
KR (1) KR20190064573A (https=)
CN (1) CN110461329A (https=)
AU (1) AU2017313839A1 (https=)
BR (1) BR112019003130A2 (https=)
CA (1) CA3034258A1 (https=)
EA (1) EA201990512A1 (https=)
MX (1) MX2019001979A (https=)
SG (2) SG11201901320WA (https=)
WO (1) WO2018035446A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201791982A1 (ru) 2015-03-09 2020-02-17 Интекрин Терапьютикс, Инк. Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
WO2020243058A1 (en) * 2019-05-30 2020-12-03 Coherus Biosciences, Inc. Compositions and methods to treat cancer
JP2022104747A (ja) * 2020-12-29 2022-07-11 国立研究開発法人国立がん研究センター 抗ウイルス剤
JP2022104746A (ja) * 2020-12-29 2022-07-11 国立研究開発法人国立がん研究センター 抗がん剤

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000256208A (ja) * 1999-03-09 2000-09-19 Univ Osaka 抗炎症剤、単球系細胞の増殖抑制剤
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2010265216A (ja) * 2009-05-14 2010-11-25 Takeda Chem Ind Ltd 複素環化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102056756B1 (ko) * 2013-01-30 2019-12-17 인테크린 테라퓨틱스, 아이엔씨. 다발성 경화증의 치료를 위한 PPARγ 작용제
ES2866883T3 (es) * 2016-06-08 2021-10-20 Support Venture Gmbh Combinaciones farmacéuticas para el tratamiento del cáncer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000256208A (ja) * 1999-03-09 2000-09-19 Univ Osaka 抗炎症剤、単球系細胞の増殖抑制剤
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2010265216A (ja) * 2009-05-14 2010-11-25 Takeda Chem Ind Ltd 複素環化合物

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
ADVANCES IN HEMATOLOGY, vol. 2009, JPN6021020544, 2009, pages 6 pages, ISSN: 0004699789 *
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, JPN6021020555, 2013, pages 979 - 992, ISSN: 0004518948 *
BLOOD, vol. 113(16), JPN6021020549, 2009, pages 3655 - 3665, ISSN: 0004518944 *
BLOOD, vol. 118(22), JPN6021020543, 2011, pages 5872 - 5882, ISSN: 0004699788 *
CANCER CAUSES CONTROL, vol. 20, JPN6021020554, 2009, pages 193 - 199, ISSN: 0004518947 *
CLINICAL IMMUNOLOGY, vol. 113, JPN6021020551, 2004, pages 203 - 213, ISSN: 0004518945 *
CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, vol. 58, JPN6021020546, 2006, pages 1 - 14, ISSN: 0004518942 *
DIABETES CARE, vol. 37, JPN6021020540, 2014, pages 1918 - 1923, ISSN: 0004699786 *
EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 755, JPN6021020557, 2015, pages 50 - 57, ISSN: 0004518949 *
HTTPS://PROFESSIONAL.DIABETES.ORG/ABSTRACT/T0903131-SELECTIVE-MODULATOR-PPAR-GAMMA-ACTIVITY-INCREASE, JPN6021020541, 2004, ISSN: 0004699787 *
INTERNATIONAL JOURNAL OF HEMATOLOGY, vol. 83(3), JPN6021020552, 2006, pages 254 - 258, ISSN: 0004518946 *
LIFE SCIENCES, vol. 135, JPN6021020547, 2015, pages 55 - 67, ISSN: 0004518943 *
PPAR RESEARCH, vol. 2008, JPN6021020537, 2008, pages 9 pages, ISSN: 0004699785 *

Also Published As

Publication number Publication date
EP3500268A4 (en) 2020-04-15
EA201990512A1 (ru) 2019-08-30
CA3034258A1 (en) 2018-02-22
KR20190064573A (ko) 2019-06-10
AU2017313839A1 (en) 2019-03-07
BR112019003130A2 (pt) 2019-05-21
CN110461329A (zh) 2019-11-15
US20210379049A1 (en) 2021-12-09
MX2019001979A (es) 2019-09-19
SG10202101501PA (en) 2021-03-30
JP2022116304A (ja) 2022-08-09
SG11201901320WA (en) 2019-03-28
WO2018035446A1 (en) 2018-02-22
EP3500268A1 (en) 2019-06-26

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