JP2019524877A5 - - Google Patents
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- Publication number
- JP2019524877A5 JP2019524877A5 JP2019520483A JP2019520483A JP2019524877A5 JP 2019524877 A5 JP2019524877 A5 JP 2019524877A5 JP 2019520483 A JP2019520483 A JP 2019520483A JP 2019520483 A JP2019520483 A JP 2019520483A JP 2019524877 A5 JP2019524877 A5 JP 2019524877A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- formula
- carotenoid compound
- microbial
- gastrointestinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims 22
- -1 methylethyl Chemical group 0.000 claims 12
- 235000021466 carotenoid Nutrition 0.000 claims 11
- 230000000813 microbial effect Effects 0.000 claims 11
- 230000002496 gastric effect Effects 0.000 claims 8
- 230000009286 beneficial effect Effects 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 238000012423 maintenance Methods 0.000 claims 6
- 230000000069 prophylactic effect Effects 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 5
- 241001465754 Metazoa Species 0.000 claims 4
- 230000001580 bacterial effect Effects 0.000 claims 4
- 244000052616 bacterial pathogen Species 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 230000036541 health Effects 0.000 claims 4
- 244000144972 livestock Species 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 230000000770 proinflammatory effect Effects 0.000 claims 4
- 241000251468 Actinopterygii Species 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 3
- 230000004888 barrier function Effects 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 210000005027 intestinal barrier Anatomy 0.000 claims 3
- 230000007358 intestinal barrier function Effects 0.000 claims 3
- 244000005700 microbiome Species 0.000 claims 3
- 241000272517 Anseriformes Species 0.000 claims 2
- 241000193830 Bacillus <bacterium> Species 0.000 claims 2
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 241000282412 Homo Species 0.000 claims 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 210000000936 intestine Anatomy 0.000 claims 2
- 239000002207 metabolite Substances 0.000 claims 2
- 210000004877 mucosa Anatomy 0.000 claims 2
- 230000036470 plasma concentration Effects 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000283707 Capra Species 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 claims 1
- 208000015943 Coeliac disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010774 Constipation Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 208000027244 Dysbiosis Diseases 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 241000287828 Gallus gallus Species 0.000 claims 1
- 206010017964 Gastrointestinal infection Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000001145 Metabolic Syndrome Diseases 0.000 claims 1
- 241000589323 Methylobacterium Species 0.000 claims 1
- 206010028116 Mucosal inflammation Diseases 0.000 claims 1
- 201000010927 Mucositis Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
- 241001494479 Pecora Species 0.000 claims 1
- 241000286209 Phasianidae Species 0.000 claims 1
- 241000186547 Sporosarcina Species 0.000 claims 1
- 241000191940 Staphylococcus Species 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 206010000059 abdominal discomfort Diseases 0.000 claims 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 claims 1
- 230000037147 athletic performance Effects 0.000 claims 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 235000013330 chicken meat Nutrition 0.000 claims 1
- 201000003146 cystitis Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 230000007140 dysbiosis Effects 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 244000005709 gut microbiome Species 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 230000035800 maturation Effects 0.000 claims 1
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 claims 1
- 230000004770 neurodegeneration Effects 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 208000020016 psychiatric disease Diseases 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 201000005671 spondyloarthropathy Diseases 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16175832.1 | 2016-06-22 | ||
| EP16175832 | 2016-06-22 | ||
| PCT/EP2017/065348 WO2017220708A1 (en) | 2016-06-22 | 2017-06-22 | Microbial carotenoids affecting gut microbial composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524877A JP2019524877A (ja) | 2019-09-05 |
| JP2019524877A5 true JP2019524877A5 (https=) | 2020-07-27 |
| JP6966543B2 JP6966543B2 (ja) | 2021-11-17 |
Family
ID=56203217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019520483A Active JP6966543B2 (ja) | 2016-06-22 | 2017-06-22 | 消化管内微生物組成に影響を及ぼす微生物カロテノイド |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11324717B2 (https=) |
| EP (1) | EP3474862B1 (https=) |
| JP (1) | JP6966543B2 (https=) |
| KR (1) | KR102413408B1 (https=) |
| CN (1) | CN109641006B (https=) |
| AU (1) | AU2017281589B2 (https=) |
| BR (1) | BR112018076485A8 (https=) |
| CA (1) | CA3028031C (https=) |
| IL (1) | IL263683B (https=) |
| MX (1) | MX390386B (https=) |
| RU (1) | RU2759600C2 (https=) |
| WO (1) | WO2017220708A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014036182A2 (en) | 2012-08-29 | 2014-03-06 | California Institute Of Technology | Diagnosis and treatment of autism spectrum disorder |
| WO2016069801A1 (en) | 2014-10-30 | 2016-05-06 | California Institute Of Technology | Compositions and methods comprising bacteria for improving behavior in neurodecelopmental disorders |
| EA201790811A1 (ru) | 2014-10-30 | 2017-11-30 | Калифорния Инститьют Оф Текнолоджи | Содержащие бактерии композиции и способы для улучшения видов поведения при нарушениях неврологического развития |
| US20200023018A1 (en) * | 2017-02-07 | 2020-01-23 | California Institute Of Technology | Modulation of gut microbiota in huntington's disease and rett syndrome |
| JP7460531B2 (ja) | 2017-12-05 | 2024-04-02 | バイオピーエルエックス，インコーポレイティド | 微生物感染を防ぐための方法および組成物 |
| AU2019328475B2 (en) * | 2018-08-29 | 2023-02-16 | Dsm Ip Assets B.V. | Formulations for improving gut health |
| CN110283754B (zh) * | 2019-07-11 | 2021-02-02 | 中国科学院北京基因组研究所 | 用于类风湿关节炎炎症状态评估及预后评价的肠道微生物菌群 |
| KR102369996B1 (ko) * | 2020-04-21 | 2022-03-02 | 박선민 | 대사성 질환과 안질환의 예방 및 건강 유지를 위한 장내 미생물 검사 기반 맞춤형 프리바이오틱스 또는 프로바이오틱스 정보 제공방법 |
| CN115606802A (zh) * | 2022-10-21 | 2023-01-17 | 中国农业大学 | 番茄红素在制备修复肠屏障损伤的产品中的应用 |
| WO2025262090A1 (en) | 2024-06-18 | 2025-12-26 | Dsm Ip Assets B.V. | Combination of carotenoids and inulin and uses thereof |
| CN119184223A (zh) * | 2024-10-14 | 2024-12-27 | 元医(杭州)科技有限公司 | 一种基于耐辐射奇球菌素的功能宠物食品及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006083779A2 (en) * | 2005-01-31 | 2006-08-10 | Mylan Laboratories, Inc. | Pharmaceutical composition comprising hydroxylated nebivolol |
| GB0524873D0 (en) * | 2005-12-06 | 2006-01-11 | New Royal Holloway & Bedford | Bacterial production of carotenoids |
| GB201013041D0 (en) | 2010-08-03 | 2010-09-15 | Royal Holloway & New Bedford College | Carotenoids |
-
2017
- 2017-06-22 WO PCT/EP2017/065348 patent/WO2017220708A1/en not_active Ceased
- 2017-06-22 US US16/311,431 patent/US11324717B2/en active Active
- 2017-06-22 BR BR112018076485A patent/BR112018076485A8/pt not_active Application Discontinuation
- 2017-06-22 CN CN201780051160.0A patent/CN109641006B/zh active Active
- 2017-06-22 KR KR1020197001707A patent/KR102413408B1/ko active Active
- 2017-06-22 EP EP17732101.5A patent/EP3474862B1/en active Active
- 2017-06-22 AU AU2017281589A patent/AU2017281589B2/en active Active
- 2017-06-22 CA CA3028031A patent/CA3028031C/en active Active
- 2017-06-22 MX MX2018016118A patent/MX390386B/es unknown
- 2017-06-22 RU RU2019101481A patent/RU2759600C2/ru active
- 2017-06-22 JP JP2019520483A patent/JP6966543B2/ja active Active
-
2018
- 2018-12-12 IL IL263683A patent/IL263683B/en unknown
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