JP2019524834A5 - - Google Patents
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- Publication number
- JP2019524834A5 JP2019524834A5 JP2019508879A JP2019508879A JP2019524834A5 JP 2019524834 A5 JP2019524834 A5 JP 2019524834A5 JP 2019508879 A JP2019508879 A JP 2019508879A JP 2019508879 A JP2019508879 A JP 2019508879A JP 2019524834 A5 JP2019524834 A5 JP 2019524834A5
- Authority
- JP
- Japan
- Prior art keywords
- therapeutic agent
- epilepsy
- agent according
- patient
- syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662376488P | 2016-08-18 | 2016-08-18 | |
| US62/376,488 | 2016-08-18 | ||
| PCT/US2017/047505 WO2018035408A1 (en) | 2016-08-18 | 2017-08-18 | Methods of treating developmental disorders with biguanides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019524834A JP2019524834A (ja) | 2019-09-05 |
| JP2019524834A5 true JP2019524834A5 (https=) | 2020-09-24 |
Family
ID=61190982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019508879A Pending JP2019524834A (ja) | 2016-08-18 | 2017-08-18 | ビグアナイド系による発達障害の治療方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10123979B2 (https=) |
| EP (1) | EP3484452A4 (https=) |
| JP (1) | JP2019524834A (https=) |
| KR (1) | KR20190039974A (https=) |
| CN (1) | CN109715144A (https=) |
| AU (1) | AU2017313823A1 (https=) |
| CA (1) | CA3033967A1 (https=) |
| MX (1) | MX2019001937A (https=) |
| WO (1) | WO2018035408A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014159247A1 (en) | 2013-03-14 | 2014-10-02 | University Of Florida Research Foundation, Inc. | Di-amino acid repeat-containing proteins associated with als |
| US10509045B2 (en) | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| JP2019524834A (ja) | 2016-08-18 | 2019-09-05 | オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | ビグアナイド系による発達障害の治療方法 |
| WO2018195110A1 (en) * | 2017-04-17 | 2018-10-25 | University Of Florida Research Foundation, Incorporated | Regolation of ran translation by pkr and eif2a-p pathways |
| JP2020535448A (ja) | 2017-09-25 | 2020-12-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | Ｒａｎタンパク質の検出のための免役アッセイ |
| US11903910B2 (en) | 2017-09-26 | 2024-02-20 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders |
| GB201912760D0 (en) * | 2019-09-05 | 2019-10-23 | Healx Ltd | Treatment |
| WO2021055880A1 (en) | 2019-09-20 | 2021-03-25 | University Of Florida Researchfoundation, Incorporated | Detection of antibodies against ran proteins from serum and tissue lysates |
| GB202008699D0 (en) * | 2020-06-09 | 2020-07-22 | Healx Ltd | Treatment |
| CN113318111B (zh) * | 2021-06-21 | 2026-02-03 | 浙江大学 | Nav1.1激动剂在制备治疗自闭症的药物中的应用 |
| WO2023102111A1 (en) * | 2021-12-01 | 2023-06-08 | University Of Florida Research Foundation, Incorporated | Small molecule inhibitors of repeat associated non-aug (ran) translation and combination therapies |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6099859A (en) * | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
| AU2003261298A1 (en) * | 2002-08-02 | 2004-02-23 | Penwest Pharmaceuticals Company | Sustained release formulations of metformin |
| US20060147947A1 (en) * | 2002-12-04 | 2006-07-06 | Javier Apfeld | AMPK pathway components |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| WO2008097861A2 (en) * | 2007-02-02 | 2008-08-14 | Braincells, Inc. | MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS |
| CN102058888B (zh) * | 2009-05-01 | 2014-06-11 | 常州高新技术产业开发区三维工业技术研究所有限公司 | 一种治疗能量代谢异常的药物组合物和其应用 |
| EP2653158B1 (en) * | 2010-12-13 | 2017-07-05 | Fukuoka University | Therapeutic agent for blood-brain barrier disruption syndrome |
| EP3013371A4 (en) * | 2013-06-26 | 2017-04-26 | Rett Syndrome Research Trust | Rett syndrome and treatments therefore |
| JP2019524834A (ja) | 2016-08-18 | 2019-09-05 | オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | ビグアナイド系による発達障害の治療方法 |
-
2017
- 2017-08-18 JP JP2019508879A patent/JP2019524834A/ja active Pending
- 2017-08-18 WO PCT/US2017/047505 patent/WO2018035408A1/en not_active Ceased
- 2017-08-18 CA CA3033967A patent/CA3033967A1/en not_active Abandoned
- 2017-08-18 AU AU2017313823A patent/AU2017313823A1/en not_active Abandoned
- 2017-08-18 CN CN201780057960.3A patent/CN109715144A/zh active Pending
- 2017-08-18 MX MX2019001937A patent/MX2019001937A/es unknown
- 2017-08-18 EP EP17842173.1A patent/EP3484452A4/en not_active Withdrawn
- 2017-08-18 KR KR1020197006647A patent/KR20190039974A/ko not_active Ceased
- 2017-08-18 US US15/680,417 patent/US10123979B2/en active Active
-
2018
- 2018-10-11 US US16/157,653 patent/US10426746B2/en active Active
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