JP2019523008A5 - - Google Patents
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- Publication number
- JP2019523008A5 JP2019523008A5 JP2019504923A JP2019504923A JP2019523008A5 JP 2019523008 A5 JP2019523008 A5 JP 2019523008A5 JP 2019504923 A JP2019504923 A JP 2019504923A JP 2019504923 A JP2019504923 A JP 2019504923A JP 2019523008 A5 JP2019523008 A5 JP 2019523008A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant virus
- recombinant
- virus
- administering
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000700605 Viruses Species 0.000 claims 26
- 206010028980 Neoplasm Diseases 0.000 claims 7
- 201000011510 cancer Diseases 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 241000700588 Human alphaherpesvirus 1 Species 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 108010074708 B7-H1 Antigen Proteins 0.000 claims 1
- 102000008096 B7-H1 Antigen Human genes 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 210000000822 natural killer cell Anatomy 0.000 claims 1
- 230000029812 viral genome replication Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022129037A JP2022163182A (ja) | 2016-07-29 | 2022-08-12 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
| JP2024096293A JP2024123088A (ja) | 2016-07-29 | 2024-06-13 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662368822P | 2016-07-29 | 2016-07-29 | |
| US62/368,822 | 2016-07-29 | ||
| US201762479671P | 2017-03-31 | 2017-03-31 | |
| US62/479,671 | 2017-03-31 | ||
| PCT/US2017/044683 WO2018023114A1 (en) | 2016-07-29 | 2017-07-31 | Expression of pten-long with ocolytic viruses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022129037A Division JP2022163182A (ja) | 2016-07-29 | 2022-08-12 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523008A JP2019523008A (ja) | 2019-08-22 |
| JP2019523008A5 true JP2019523008A5 (enExample) | 2020-09-10 |
| JP7638061B2 JP7638061B2 (ja) | 2025-03-03 |
Family
ID=61016870
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019504923A Active JP7638061B2 (ja) | 2016-07-29 | 2017-07-31 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
| JP2022129037A Pending JP2022163182A (ja) | 2016-07-29 | 2022-08-12 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
| JP2024096293A Pending JP2024123088A (ja) | 2016-07-29 | 2024-06-13 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022129037A Pending JP2022163182A (ja) | 2016-07-29 | 2022-08-12 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
| JP2024096293A Pending JP2024123088A (ja) | 2016-07-29 | 2024-06-13 | 腫瘍溶解性ウイルスによるＰＴＥＮ－Ｌｏｎｇの発現 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20200085890A1 (enExample) |
| EP (2) | EP3490574B8 (enExample) |
| JP (3) | JP7638061B2 (enExample) |
| KR (1) | KR102780496B1 (enExample) |
| CN (1) | CN110087662A (enExample) |
| AU (1) | AU2017301901B2 (enExample) |
| BR (1) | BR112019001737A2 (enExample) |
| CA (1) | CA3032412A1 (enExample) |
| SG (1) | SG11201900815UA (enExample) |
| WO (1) | WO2018023114A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| CN110494543A (zh) | 2016-10-19 | 2019-11-22 | 弗洛设计声能学公司 | 通过声学的亲和细胞提取 |
| EP3833765A1 (en) * | 2017-08-09 | 2021-06-16 | The Ohio State Innovation Foundation | Oncolytic virus carrying e-cadherin and uses thereof |
| CN112004923A (zh) | 2017-11-22 | 2020-11-27 | 迈索布拉斯特国际有限公司 | 细胞组合物及治疗方法 |
| KR20220066413A (ko) | 2017-12-14 | 2022-05-24 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
| CN108484780A (zh) * | 2018-04-16 | 2018-09-04 | 河南大学 | 一种融合蛋白PTEN-L-p53及其应用 |
| CN114127122A (zh) | 2019-04-12 | 2022-03-01 | 治疗生物科学公司 | 制备磷酸酶与张力蛋白同源物（pten）融合物的组合物和方法 |
| CA3149478A1 (en) * | 2019-08-05 | 2021-02-11 | Mesoblast International Sarl | Cellular compositions comprising viral vectors and methods of treatment |
| CN111763260B (zh) * | 2020-06-11 | 2022-03-29 | 四川大学华西医院 | 一种PTEN-Long多克隆抗体及其制备方法和用途 |
| WO2024163335A2 (en) * | 2023-01-30 | 2024-08-08 | The Board Of Regents Of The University Of Texas System | Pten gene therapy vectors and uses thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1601438A (enExample) | 1968-10-17 | 1970-08-24 | ||
| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US6261834B1 (en) | 1991-11-08 | 2001-07-17 | Research Corporation Technologies, Inc. | Vector for gene therapy |
| GB9801930D0 (en) * | 1998-01-29 | 1998-03-25 | Univ London | Mutant herpes simplex viruses and uses thereof |
| WO2005086922A2 (en) * | 2004-03-10 | 2005-09-22 | Board Of Regents, University Of Texas System | Oncolytic adenovirus armed with therapeutic genes |
| WO2005107474A2 (en) * | 2004-04-30 | 2005-11-17 | Introgen Therapeutics, Inc. | Oncolytic adenovirus armed with therapeutic genes |
| CN101180397A (zh) * | 2005-03-09 | 2008-05-14 | 得克萨斯大学体系董事会 | 用于癌症治疗基因的肿瘤选择性和高效率表达的新型hTMC启动子和载体 |
| JP5767117B2 (ja) * | 2009-02-17 | 2015-08-19 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｃｏｌｕｍｂｉａ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎ Ｔｈｅ Ｃｉｔｙ Ｏｆ Ｎｅｗ Ｙｏｒｋ | 腫瘍の治療に使用できるｐｔｅｎの細胞外形態の同定 |
| CA3017717A1 (en) * | 2010-02-17 | 2011-08-25 | Ramon Parsons | Use of pten-long leader sequence for transmembrane delivery of molecules |
| KR101497035B1 (ko) * | 2010-04-26 | 2015-02-27 | 주식회사 녹십자 | 종양 특이적 프로모터 및 이를 포함하는 종양살상 바이러스 벡터 |
| EP2494978A1 (en) * | 2011-03-03 | 2012-09-05 | Bundesrepublik Deutschland, Letztvertreten Durch Den Präsidenten Des Paul-Ehrlich-Instituts | Enhanced tumor therapy by tumor stem cell targeted oncolytic viruses |
| US9863935B2 (en) * | 2012-05-08 | 2018-01-09 | H. Lee Moffitt Cancer And Research Institute, Inc. | Predictive biomarkers for CTLA-4 blockade therapy and for PD-1 blockade therapy |
| WO2014142235A1 (ja) * | 2013-03-13 | 2014-09-18 | Li Zhong | 微小胞及びその製造方法 |
| JP6588024B2 (ja) * | 2013-10-28 | 2019-10-09 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | 腫瘍溶解性ｈｓｖベクター |
| GB201408297D0 (en) * | 2014-05-12 | 2014-06-25 | Virttu Biolog Ltd | Treatment of cancer |
-
2017
- 2017-07-31 JP JP2019504923A patent/JP7638061B2/ja active Active
- 2017-07-31 EP EP17835414.8A patent/EP3490574B8/en active Active
- 2017-07-31 SG SG11201900815UA patent/SG11201900815UA/en unknown
- 2017-07-31 CA CA3032412A patent/CA3032412A1/en active Pending
- 2017-07-31 KR KR1020197005487A patent/KR102780496B1/ko active Active
- 2017-07-31 WO PCT/US2017/044683 patent/WO2018023114A1/en not_active Ceased
- 2017-07-31 BR BR112019001737-2A patent/BR112019001737A2/pt active Search and Examination
- 2017-07-31 EP EP24176375.4A patent/EP4403229A3/en active Pending
- 2017-07-31 US US16/321,777 patent/US20200085890A1/en active Pending
- 2017-07-31 CN CN201780059869.5A patent/CN110087662A/zh active Pending
- 2017-07-31 AU AU2017301901A patent/AU2017301901B2/en active Active
-
2022
- 2022-08-12 JP JP2022129037A patent/JP2022163182A/ja active Pending
-
2023
- 2023-01-06 US US18/151,195 patent/US20230338443A1/en active Pending
-
2024
- 2024-06-13 JP JP2024096293A patent/JP2024123088A/ja active Pending
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