JP2019518792A5 - - Google Patents

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Publication number
JP2019518792A5
JP2019518792A5 JP2019515787A JP2019515787A JP2019518792A5 JP 2019518792 A5 JP2019518792 A5 JP 2019518792A5 JP 2019515787 A JP2019515787 A JP 2019515787A JP 2019515787 A JP2019515787 A JP 2019515787A JP 2019518792 A5 JP2019518792 A5 JP 2019518792A5
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JP
Japan
Prior art keywords
group
substituted
bone
alkyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2019515787A
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English (en)
Japanese (ja)
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JP2019518792A (ja
JP7602217B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/035764 external-priority patent/WO2017210611A1/en
Publication of JP2019518792A publication Critical patent/JP2019518792A/ja
Publication of JP2019518792A5 publication Critical patent/JP2019518792A5/ja
Priority to JP2022117577A priority Critical patent/JP2022166008A/ja
Priority to JP2023171669A priority patent/JP2023181185A/ja
Application granted granted Critical
Publication of JP7602217B2 publication Critical patent/JP7602217B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019515787A 2016-06-03 2017-06-02 ビスホスホネート・キノロン複合体及びそれらの用途 Active JP7602217B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022117577A JP2022166008A (ja) 2016-06-03 2022-07-22 ビスホスホネート・キノロン複合体及びそれらの用途
JP2023171669A JP2023181185A (ja) 2016-06-03 2023-10-02 ビスホスホネート・キノロン複合体及びそれらの用途

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662345370P 2016-06-03 2016-06-03
US62/345,370 2016-06-03
US201662357727P 2016-07-01 2016-07-01
US62/357,727 2016-07-01
US201762448060P 2017-01-19 2017-01-19
US62/448,060 2017-01-19
PCT/US2017/035764 WO2017210611A1 (en) 2016-06-03 2017-06-02 Bisphosphonate quinolone conjugates and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022117577A Division JP2022166008A (ja) 2016-06-03 2022-07-22 ビスホスホネート・キノロン複合体及びそれらの用途

Publications (3)

Publication Number Publication Date
JP2019518792A JP2019518792A (ja) 2019-07-04
JP2019518792A5 true JP2019518792A5 (https=) 2019-08-15
JP7602217B2 JP7602217B2 (ja) 2024-12-18

Family

ID=60479075

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019515787A Active JP7602217B2 (ja) 2016-06-03 2017-06-02 ビスホスホネート・キノロン複合体及びそれらの用途
JP2022117577A Withdrawn JP2022166008A (ja) 2016-06-03 2022-07-22 ビスホスホネート・キノロン複合体及びそれらの用途
JP2023171669A Pending JP2023181185A (ja) 2016-06-03 2023-10-02 ビスホスホネート・キノロン複合体及びそれらの用途

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022117577A Withdrawn JP2022166008A (ja) 2016-06-03 2022-07-22 ビスホスホネート・キノロン複合体及びそれらの用途
JP2023171669A Pending JP2023181185A (ja) 2016-06-03 2023-10-02 ビスホスホネート・キノロン複合体及びそれらの用途

Country Status (4)

Country Link
EP (1) EP3464307A4 (https=)
JP (3) JP7602217B2 (https=)
CN (1) CN110114366A (https=)
WO (1) WO2017210611A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017210611A1 (en) * 2016-06-03 2017-12-07 Biovinc, Llc. Bisphosphonate quinolone conjugates and uses thereof
KR20180115979A (ko) * 2017-04-14 2018-10-24 연세대학교 산학협력단 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물
US12285489B2 (en) * 2018-06-26 2025-04-29 Frank Hallock Ebetino Bone targeted antimicrobial oxazolidinone related compounds, formulations thereof, and uses thereof

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921475A (en) 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
US5087240A (en) 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US5163899A (en) 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
GB8804164D0 (en) 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5008110A (en) 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5088977A (en) 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
DK0431519T3 (da) 1989-12-04 1994-07-04 Searle & Co System til transdermal indgivelse af albuterol
IE912115A1 (en) * 1990-06-25 1992-01-01 Takeda Chemical Industries Ltd Bisphosphonic acid derivatives, their production and use
US5352456A (en) 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
DE69228827T2 (de) 1991-12-18 1999-10-21 Minnesota Mining And Mfg. Co., Saint Paul Mehrschichtige sperrstrukturen
ATE132381T1 (de) 1992-01-29 1996-01-15 Voelkl Franz Ski Ballspielschläger, insbesondere tennisschläger
FI945595A7 (fi) * 1992-05-29 1994-11-28 Procter & Gamble Pharmaceuticals Inc Tiosubstituoituja typpipitoisia heterosyklisiä fosfonaattiyhdisteitä e pänormaalin kalsium- ja fosfaattiaineenvaihdunnan hoitamiseksi
US6333424B1 (en) * 1996-10-09 2001-12-25 Eliza Nor Biopharmaceuticals, Inc. Therapeutic derivatives of diphosphonates
US8586781B2 (en) * 1998-04-02 2013-11-19 Mbc Pharma, Inc. Bone targeted therapeutics and methods of making and using the same
EP1881974A4 (en) * 2005-04-21 2011-03-16 Targanta Therapeutics Inc PHOSPHONE FLUOROQUINOLONES, THEIR ANTIBACTERIAL ANALOGUES, AND METHODS FOR PREVENTING AND TREATING BONE AND JOINT INFECTIONS
JP5161872B2 (ja) * 2006-05-12 2013-03-13 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア 細菌感染に対する抗微生物療法
CL2007003332A1 (es) * 2006-11-24 2008-06-20 Actelion Pharmaceuticals Ltd Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas.
WO2010071826A2 (en) * 2008-12-19 2010-06-24 University Of Florida Research Foundation, Inc. Methods for treating osteoclast-related disease, compounds and compositions thereof
US20140051652A1 (en) * 2012-08-20 2014-02-20 Kingsley Yianomah Quartey Treatment for Migraine Headache
WO2017210611A1 (en) * 2016-06-03 2017-12-07 Biovinc, Llc. Bisphosphonate quinolone conjugates and uses thereof

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