JP2019518742A5 - - Google Patents

Download PDF

Info

Publication number
JP2019518742A5
JP2019518742A5 JP2018559937A JP2018559937A JP2019518742A5 JP 2019518742 A5 JP2019518742 A5 JP 2019518742A5 JP 2018559937 A JP2018559937 A JP 2018559937A JP 2018559937 A JP2018559937 A JP 2018559937A JP 2019518742 A5 JP2019518742 A5 JP 2019518742A5
Authority
JP
Japan
Prior art keywords
antibody
use according
isotype
active fragment
immunologically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018559937A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019518742A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/031673 external-priority patent/WO2017196793A1/en
Publication of JP2019518742A publication Critical patent/JP2019518742A/ja
Publication of JP2019518742A5 publication Critical patent/JP2019518742A5/ja
Pending legal-status Critical Current

Links

JP2018559937A 2016-05-09 2017-05-09 Cd47抗体およびその使用方法 Pending JP2019518742A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662333631P 2016-05-09 2016-05-09
US62/333,631 2016-05-09
PCT/US2017/031673 WO2017196793A1 (en) 2016-05-09 2017-05-09 Cd47 antibodies and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2019518742A JP2019518742A (ja) 2019-07-04
JP2019518742A5 true JP2019518742A5 (enExample) 2020-06-18

Family

ID=60267183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018559937A Pending JP2019518742A (ja) 2016-05-09 2017-05-09 Cd47抗体およびその使用方法

Country Status (6)

Country Link
US (2) US20200255515A1 (enExample)
EP (1) EP3454900A4 (enExample)
JP (1) JP2019518742A (enExample)
AR (1) AR112048A1 (enExample)
TW (1) TW201741340A (enExample)
WO (1) WO2017196793A1 (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018252193B2 (en) 2017-04-14 2024-12-12 Tallac Therapeutics, Inc. Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use
EP3704157A1 (en) 2017-11-01 2020-09-09 Hummingbird Bioscience Holdings Pte. Ltd. Cd47 antigen-binding molecules
AR113862A1 (es) 2017-12-01 2020-06-17 Seattle Genetics Inc Anticuerpos anti-cd47 y sus usos para tratar cáncer
US11555071B2 (en) 2018-06-03 2023-01-17 Lamkap Bio Beta Ltd. Bispecific antibodies against CEACAM5 and CD47
CN110577597B (zh) * 2018-06-11 2021-10-22 康诺亚生物医药科技(成都)有限公司 一种阻断CD47和SIRPα相互作用的抗体
JP7561775B2 (ja) 2019-06-07 2024-10-04 エーエルエックス オンコロジー インコーポレイテッド 血清学的アッセイにおいてcd47に結合する薬物の干渉を低減するための方法及び試薬
EP3999107A1 (en) 2019-07-16 2022-05-25 Gilead Sciences, Inc. Hiv vaccines and methods of making and using
US20220257729A1 (en) * 2019-07-17 2022-08-18 The Board Of Trustees Of The Leland Stanford Junior University Combination of integrin-targeting knottin-fc fusion and anti-cd47 antibody for the treatment of cancer
US12441807B2 (en) 2019-09-18 2025-10-14 Lamkap Bio Alpha AG Bispecific antibodies against CEACAM5 and CD3
US11795223B2 (en) 2019-10-18 2023-10-24 Forty Seven, Inc. Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia
MX2022005123A (es) 2019-10-31 2022-05-30 Forty Seven Inc Tratamiento basado en anti-cd47 y anti-cd20 para cancer hematologico.
EP3831849A1 (en) 2019-12-02 2021-06-09 LamKap Bio beta AG Bispecific antibodies against ceacam5 and cd47
PE20230160A1 (es) 2019-12-17 2023-02-01 Pfizer Anticuerpos especificos para cd47, pd-l1 y sus usos
MX2022007930A (es) 2019-12-24 2022-08-08 Carna Biosciences Inc Compuestos moduladores de diacilglicerol quinasa.
BR112022014623A2 (pt) 2020-02-14 2022-09-13 Jounce Therapeutics Inc Anticorpos e proteínas de fusão que se ligam a ccr8 e usos dos mesmos
US11920136B2 (en) 2020-02-28 2024-03-05 Tallac Therapeutics, Inc. Transglutaminase-mediated conjugation
WO2021191870A1 (en) 2020-03-27 2021-09-30 Dcprime B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
EP4171617A1 (en) 2020-06-30 2023-05-03 Mendus B.V. Use of leukemia-derived cells in ovarian cancer vaccines
AU2021346729A1 (en) * 2020-09-28 2023-05-11 Shanghai Henlius Biologics Co., Ltd. Anti-cd47 antibodies and methods of use
US20220196651A1 (en) 2020-12-06 2022-06-23 ALX Oncology Inc. Multimers for reducing the interference of drugs that bind cd47 in serological assays
EP4055055B1 (en) 2020-12-18 2023-11-22 LamKap Bio beta AG Bispecific antibodies against ceacam5 and cd47
US20220305100A1 (en) 2021-03-12 2022-09-29 Dcprime B.V. Methods of vaccination and use of cd47 blockade
TW202302145A (zh) 2021-04-14 2023-01-16 美商基利科學股份有限公司 CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症
KR20240005901A (ko) 2021-06-23 2024-01-12 길리애드 사이언시즈, 인코포레이티드 디아실글리세롤 키나제 조절 화합물
WO2022271684A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
JP7686086B2 (ja) 2021-06-23 2025-05-30 ギリアード サイエンシーズ, インコーポレイテッド ジアシルグリエルコール(diacylglyercol)キナーゼ調節化合物
WO2022271659A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
US11807685B2 (en) * 2021-08-05 2023-11-07 The Uab Research Foundation Anti-CD47 antibody and uses thereof
AU2022375782A1 (en) 2021-10-28 2024-05-02 Gilead Sciences, Inc. Pyridizin-3(2h)-one derivatives
PE20241186A1 (es) 2021-10-29 2024-06-03 Gilead Sciences Inc Compuestos de cd73
CA3237577A1 (en) 2021-12-22 2023-06-29 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
EP4452414A2 (en) 2021-12-22 2024-10-30 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
TW202340168A (zh) 2022-01-28 2023-10-16 美商基利科學股份有限公司 Parp7抑制劑
WO2023178181A1 (en) 2022-03-17 2023-09-21 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
JP2025509662A (ja) 2022-03-24 2025-04-11 ギリアード サイエンシーズ, インコーポレイテッド Trop-2発現がんを治療するための併用療法
TWI876305B (zh) 2022-04-05 2025-03-11 美商基利科學股份有限公司 用於治療結腸直腸癌之組合療法
WO2023205719A1 (en) 2022-04-21 2023-10-26 Gilead Sciences, Inc. Kras g12d modulating compounds
WO2023242351A1 (en) 2022-06-16 2023-12-21 Lamkap Bio Beta Ag Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
CA3260083A1 (en) 2022-07-01 2024-01-04 Gilead Sciences Inc CD73 COMPOUNDS
CN119677546A (zh) 2022-07-12 2025-03-21 吉利德科学公司 Hiv免疫原性多肽和疫苗及其用途
WO2024064668A1 (en) 2022-09-21 2024-03-28 Gilead Sciences, Inc. FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY
CN118221812A (zh) * 2022-12-14 2024-06-21 上海迈石生物技术有限公司 一种靶向cd47的单克隆抗体及其应用
US20240254118A1 (en) 2022-12-22 2024-08-01 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
AU2024252725A1 (en) 2023-04-11 2025-11-06 Gilead Sciences, Inc. Kras modulating compounds
CN121079300A (zh) 2023-04-21 2025-12-05 吉利德科学公司 Prmt5抑制剂及其用途
WO2025006720A1 (en) 2023-06-30 2025-01-02 Gilead Sciences, Inc. Kras modulating compounds
US20250066328A1 (en) 2023-07-26 2025-02-27 Gilead Sciences, Inc. Parp7 inhibitors
WO2025024811A1 (en) 2023-07-26 2025-01-30 Gilead Sciences, Inc. Parp7 inhibitors
US20250109147A1 (en) 2023-09-08 2025-04-03 Gilead Sciences, Inc. Kras g12d modulating compounds
WO2025054347A1 (en) 2023-09-08 2025-03-13 Gilead Sciences, Inc. Kras g12d modulating compounds
WO2025096589A1 (en) 2023-11-03 2025-05-08 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
WO2025137640A1 (en) 2023-12-22 2025-06-26 Gilead Sciences, Inc. Azaspiro wrn inhibitors
US20250376484A1 (en) 2024-05-21 2025-12-11 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130309246A1 (en) * 2011-02-02 2013-11-21 The Trustees Of Princeton University Jagged1 as a marker and therapeutic target for breast cancer bone metastasis
US20140140989A1 (en) * 2012-02-06 2014-05-22 Inhibrx Llc Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof
EP3578569A1 (en) * 2012-02-06 2019-12-11 Inhibrx, Inc. Cd47 antibodies and methods of use thereof
EP3003387A1 (en) * 2013-06-04 2016-04-13 Cytomx Therapeutics Inc. Compositions and methods for conjugating activatable antibodies

Similar Documents

Publication Publication Date Title
JP2019518742A5 (enExample)
JP2022031635A5 (enExample)
HRP20191609T1 (hr) Protein
CN110366560A (zh) 抗b7-h4抗体、其抗原结合片段及其医药用途
JP2014240385A5 (enExample)
JP2009114201A5 (enExample)
WO2006121852A3 (en) Anti-cd19 antibody therapy for autoimmune disease
MY184154A (en) Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
MY205774A (en) Human il-4r binding antibody, antigen binding fragment thereof, and medical use thereof
JP2017149726A5 (enExample)
JP2015534579A5 (enExample)
FI3569620T3 (fi) Ihmisen cgrp-reseptoria sitovat vasta-aineet
WO2006089133A3 (en) Anti-cd19 antibodies and uses in oncology
JP2015520758A5 (enExample)
JP2017515815A5 (enExample)
JP2012121878A5 (enExample)
ATE471946T1 (de) Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
JP2015522252A5 (enExample)
JP2016094424A5 (enExample)
JP2012046518A5 (enExample)
HRP20221088T1 (hr) Protutijela i postupci uporabe
JP2015509960A5 (enExample)
CN111511767A (zh) 抗cd27抗体、其抗原结合片段及其医药用途
EP4032550A3 (en) Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
WO2018116267A3 (en) Methods of treatment with anti-factor xi/xia antibodies