JP2019518073A5 - - Google Patents

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Publication number
JP2019518073A5
JP2019518073A5 JP2019508309A JP2019508309A JP2019518073A5 JP 2019518073 A5 JP2019518073 A5 JP 2019518073A5 JP 2019508309 A JP2019508309 A JP 2019508309A JP 2019508309 A JP2019508309 A JP 2019508309A JP 2019518073 A5 JP2019518073 A5 JP 2019518073A5
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JP
Japan
Prior art keywords
protein
composition
chrimson
fused
vector
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JP2019508309A
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English (en)
Japanese (ja)
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JP6942789B2 (ja
JP2019518073A (ja
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Priority claimed from PCT/IB2017/000663 external-priority patent/WO2017187272A1/en
Publication of JP2019518073A publication Critical patent/JP2019518073A/ja
Publication of JP2019518073A5 publication Critical patent/JP2019518073A5/ja
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Publication of JP6942789B2 publication Critical patent/JP6942789B2/ja
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JP2019508309A 2016-04-29 2017-04-28 Chrimsonを用いた光遺伝学的視覚回復 Active JP6942789B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662329692P 2016-04-29 2016-04-29
US62/329,692 2016-04-29
PCT/IB2017/000663 WO2017187272A1 (en) 2016-04-29 2017-04-28 Optogenetic visual restoration using chrimson

Publications (3)

Publication Number Publication Date
JP2019518073A JP2019518073A (ja) 2019-06-27
JP2019518073A5 true JP2019518073A5 (cg-RX-API-DMAC10.html) 2020-05-07
JP6942789B2 JP6942789B2 (ja) 2021-09-29

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ID=59253830

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019508309A Active JP6942789B2 (ja) 2016-04-29 2017-04-28 Chrimsonを用いた光遺伝学的視覚回復

Country Status (8)

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US (2) US20190269755A1 (cg-RX-API-DMAC10.html)
EP (1) EP3448411A1 (cg-RX-API-DMAC10.html)
JP (1) JP6942789B2 (cg-RX-API-DMAC10.html)
KR (1) KR102466887B1 (cg-RX-API-DMAC10.html)
CN (1) CN110267673B (cg-RX-API-DMAC10.html)
AU (2) AU2017256910B2 (cg-RX-API-DMAC10.html)
CA (1) CA3025975A1 (cg-RX-API-DMAC10.html)
WO (1) WO2017187272A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12599670B2 (en) 2014-12-12 2026-04-14 The Trustees Of The University Of Pennsylvania Composition comprising three-dimensional astrocyte bundles of bi-polar and aligned astrocyte processes and a method of making thereof
EP3442409A4 (en) 2016-04-14 2019-11-13 The Trustees of The University of Pennsylvania IMPLANTABLE LIVING ELECTRODES AND METHOD FOR USE THEREOF
EP3693060A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices
EP3693061A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using filtering and associated devices
EP3733139A1 (en) 2019-05-02 2020-11-04 Gensight Biologics Viewing apparatus and method for projecting a light signal
WO2021132903A1 (ko) * 2019-12-26 2021-07-01 고려대학교 산학협력단 광유전학 기법을 이용한 알츠하이머 질환 뇌에서의 뇌파 손상 회복 방법
WO2023158839A1 (en) * 2022-02-18 2023-08-24 The Trustees Of The University Of Pennsylvania Tissue engineered spinal tracts for functional regeneration after spinal cord injury
JP2025528188A (ja) 2022-08-11 2025-08-26 インスティテュート オブ モレキュラー アンド クリニカル オフサルモロジー バーゼル (アイオービー) ヒト錐体光受容体オプトジェネティクス構築物
CN119827471B (zh) * 2025-02-14 2025-10-03 中山大学中山眼科中心 一种体内追踪外段蛋白运输的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
JP2009502140A (ja) 2005-07-22 2009-01-29 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 光活性化陽イオンチャネルおよびその使用
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
EP1891976A1 (en) 2006-08-23 2008-02-27 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Use of light sensitive genes
CA2713755A1 (en) * 2008-02-07 2009-08-13 Ceregene, Inc. Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein
EP2679246A3 (en) 2008-04-18 2014-02-26 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Novel therapeutical tools and methods for treating blindness
DK3693025T3 (da) 2011-04-22 2022-01-10 Univ California Adenoassocierede virus-virioner med variant capsid og fremgangsmåder til anvendelse heraf
WO2013071231A1 (en) * 2011-11-12 2013-05-16 Massachusetts Institute Of Technology Channelrhodopsins for optical control of cells
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
US10882892B2 (en) * 2014-08-05 2021-01-05 Massachusetts Institute Of Technology Channelrhodopsin variants and uses thereof
JP2018533768A (ja) * 2015-11-05 2018-11-15 インスコピックス, インコーポレイテッド 光遺伝学撮像のためのシステムおよび方法
JP6966442B2 (ja) * 2015-12-04 2021-11-17 ソルボンヌ・ユニヴェルシテSorbonne Universite プロモーター及びその使用

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