JP2019515043A5 - - Google Patents
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- JP2019515043A5 JP2019515043A5 JP2019510575A JP2019510575A JP2019515043A5 JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5 JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019510575 A JP2019510575 A JP 2019510575A JP 2019515043 A5 JP2019515043 A5 JP 2019515043A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021204755A JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662332278P | 2016-05-05 | 2016-05-05 | |
| US62/332,278 | 2016-05-05 | ||
| PCT/US2017/031360 WO2017193034A1 (en) | 2016-05-05 | 2017-05-05 | Modulators of the integrated stress pathway |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Division JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515043A JP2019515043A (ja) | 2019-06-06 |
| JP2019515043A5 true JP2019515043A5 (cg-RX-API-DMAC7.html) | 2020-06-25 |
| JP6997766B2 JP6997766B2 (ja) | 2022-01-20 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019510575A Active JP6997766B2 (ja) | 2016-05-05 | 2017-05-05 | 統合的ストレス経路のモジュレーター |
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021204755A Active JP7389786B2 (ja) | 2016-05-05 | 2021-12-17 | 統合的ストレス経路のモジュレーター |
| JP2023195552A Active JP7755632B2 (ja) | 2016-05-05 | 2023-11-17 | 統合的ストレス経路のモジュレーター |
Country Status (38)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020522553A (ja) * | 2017-06-07 | 2020-07-30 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | Ａｔｆ４経路阻害剤としての化合物 |
| JP2020525513A (ja) * | 2017-07-03 | 2020-08-27 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | 癌および他の疾患を治療するためのａｔｆ４阻害剤としてのｎ−（３−（２−（４−クロロフェノキシ）アセトアミドビシクロ［１．１．１］ペンタン−１−イル）−２−シクロブタン−１−カルボキサミド誘導体および関連化合物 |
| PH12020550028B1 (en) | 2017-08-09 | 2024-05-24 | Denali Therapeutics Inc | Compounds, compositions and methods |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| UY37956A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| AU2018358160B2 (en) | 2017-11-02 | 2023-03-16 | Abbvie Inc. | Modulators of the integrated stress pathway |
| UY37958A (es) * | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| MX2020006115A (es) | 2017-12-13 | 2020-11-09 | Praxis Biotech LLC | Inhibidores de la vía de respuesta al estrés integrada. |
| US20210130308A1 (en) * | 2018-03-23 | 2021-05-06 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| MX2020013269A (es) | 2018-06-05 | 2021-02-18 | Praxis Biotech LLC | Inhibidores de la vía de respuesta al estrés integrada. |
| CA3105942A1 (en) * | 2018-07-09 | 2020-01-16 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds |
| TWI771621B (zh) * | 2018-10-11 | 2022-07-21 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| KR20210126036A (ko) * | 2019-02-13 | 2021-10-19 | 데날리 테라퓨틱스 인크. | 화합물, 조성물 및 방법 |
| CA3130511A1 (en) * | 2019-02-25 | 2020-09-03 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| WO2020216764A1 (en) | 2019-04-23 | 2020-10-29 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| KR20220004105A (ko) | 2019-04-23 | 2022-01-11 | 에보텍 인터내셔널 게엠베하 | 통합 스트레스 반응 경로의 조절제 |
| MX2021013197A (es) * | 2019-04-30 | 2022-02-24 | Calico Life Sciences Llc | Cicloalquilos sustituidos como moduladores de la vía integrada del estrés. |
| WO2020223536A1 (en) * | 2019-04-30 | 2020-11-05 | Calico Life Sciences Llc | Substituted cyclolakyls as modulators of the integrated stress pathway |
| EP3982965A4 (en) | 2019-06-12 | 2023-01-25 | Praxis Biotech LLC | INTEGRATED STRESS RESPONSE PATHWAY MODULATORS |
| PT4069691T (pt) * | 2019-12-06 | 2024-12-18 | Vertex Pharma | Tetrahidrofuranos substituídos como moduladores dos canais de sódio |
| AU2021213289A1 (en) | 2020-01-28 | 2022-07-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| US12441720B2 (en) | 2020-03-11 | 2025-10-14 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| PL4232154T3 (pl) | 2020-10-22 | 2025-02-24 | Evotec International Gmbh | Modulatory zintegrowanego szlaku odpowiedzi na stres |
| EP4232153A1 (en) | 2020-10-22 | 2023-08-30 | Evotec International GmbH | Modulators of the integrated stress response pathway |
| JP2023546226A (ja) | 2020-10-22 | 2023-11-01 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合ストレス応答経路のモジュレーター |
| AU2021397774A1 (en) * | 2020-12-10 | 2023-06-29 | Adgero Biopharmaceuticals Holdings, Inc. | Methods for treating cutaneous metastatic cancers |
| KR20250122004A (ko) * | 2024-02-05 | 2025-08-13 | 재단법인 대구경북첨단의료산업진흥재단 | 신규한 eIF2B 작용제 및 이를 포함하는 대사질환 예방 또는 치료용 조성물 |
Family Cites Families (18)
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|---|---|---|---|---|
| US5212A (en) | 1847-07-31 | Richard m | ||
| US162A (en) | 1837-04-17 | Island | ||
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| DK0495421T3 (da) | 1991-01-15 | 1996-12-09 | Alcon Lab Inc | Anvendelse af carragenaner i topiske ophthalmiske sammensætninger |
| US20070185079A1 (en) * | 2004-01-07 | 2007-08-09 | Astrazeneca Ab | Therapeutic agents I |
| GB0400196D0 (en) * | 2004-01-07 | 2004-02-11 | Astrazeneca Ab | Therapeutic agents |
| CA2574418A1 (en) | 2004-07-23 | 2006-02-02 | Susan Marie Royalty | Peptidase inhibitors |
| GB0516314D0 (en) * | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Compound |
| EP1924553A1 (en) * | 2005-08-08 | 2008-05-28 | Argenta Discovery Limited | Bicyclo[2.2.]hept-7-ylamine derivatives and their uses |
| WO2007017752A1 (en) | 2005-08-10 | 2007-02-15 | Pfizer Limited | Substituted triazole derivatives as oxytocin antagonists |
| AU2008304417B2 (en) * | 2007-09-25 | 2013-07-18 | Takeda Pharmaceutical Company Limited | Polo-like kinase inhibitors |
| US8741894B2 (en) * | 2010-03-17 | 2014-06-03 | Axikin Pharmaceuticals, Inc. | Arylsulfonamide CCR3 antagonists |
| JP5765342B2 (ja) | 2010-08-10 | 2015-08-19 | アステラス製薬株式会社 | へテロ環化合物 |
| TWI538905B (zh) * | 2010-12-22 | 2016-06-21 | Ｈ 朗德貝克公司 | 雙環［３．２．１］辛基醯胺衍生物及其用途 |
| CA2904794C (en) * | 2013-03-15 | 2021-11-23 | Peter Walter | Modulators of the eif2alpha pathway |
| US20160318856A1 (en) * | 2013-09-11 | 2016-11-03 | The Brigham And Women's Hospital, Inc. | Substituted Urea eIF2alpha Kinase Activators |
| SG11201608242XA (en) * | 2014-04-04 | 2016-10-28 | Syros Pharmaceuticals Inc | Inhibitors of cyclin-dependent kinase 7 (cdk7) |
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