JP2019513826A - 放射線療法の改善 - Google Patents
放射線療法の改善 Download PDFInfo
- Publication number
- JP2019513826A JP2019513826A JP2019503597A JP2019503597A JP2019513826A JP 2019513826 A JP2019513826 A JP 2019513826A JP 2019503597 A JP2019503597 A JP 2019503597A JP 2019503597 A JP2019503597 A JP 2019503597A JP 2019513826 A JP2019513826 A JP 2019513826A
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- Prior art keywords
- individual
- tumors
- alkyl
- irradiated
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 Bc(c(*)c1)c(*)cc1O Chemical compound Bc(c(*)c1)c(*)cc1O 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662318946P | 2016-04-06 | 2016-04-06 | |
| US62/318,946 | 2016-04-06 | ||
| AUPCT/AU2016/050674 | 2016-07-28 | ||
| PCT/AU2016/050674 WO2017173474A1 (en) | 2016-04-06 | 2016-07-28 | Improvements in cancer treatment |
| US201762461559P | 2017-02-21 | 2017-02-21 | |
| US62/461,559 | 2017-02-21 | ||
| PCT/AU2017/050299 WO2017173496A1 (en) | 2016-04-06 | 2017-04-06 | Radiotherapy improvements |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019513826A true JP2019513826A (ja) | 2019-05-30 |
| JP2019513826A5 JP2019513826A5 (enExample) | 2020-05-21 |
Family
ID=60000154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503597A Pending JP2019513826A (ja) | 2016-04-06 | 2017-04-06 | 放射線療法の改善 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11229703B2 (enExample) |
| EP (1) | EP3439642A4 (enExample) |
| JP (1) | JP2019513826A (enExample) |
| AU (1) | AU2017247006B2 (enExample) |
| CA (1) | CA3058492A1 (enExample) |
| WO (1) | WO2017173496A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017247006B2 (en) * | 2016-04-06 | 2022-05-12 | Noxopharm Limited | Radiotherapy improvements |
| JP2023512214A (ja) | 2020-01-28 | 2023-03-24 | リフレクション メディカル, インコーポレイテッド | 放射性核種および外部ビーム放射線療法の共同最適化 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007525485A (ja) * | 2003-11-19 | 2007-09-06 | ノボゲン リサーチ ピーティーワイ リミテッド | 複合的な放射線治療及び化学治療の組成物及び方法 |
| JP2012500809A (ja) * | 2008-08-29 | 2012-01-12 | ノボゲン リサーチ ピーティーワイ リミテッド | 免疫調節活性 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
| AUPQ008299A0 (en) | 1999-04-30 | 1999-05-27 | G.J. Consultants Pty Ltd | Isoflavone metabolites |
| US20090233999A1 (en) * | 1999-09-06 | 2009-09-17 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| AUPR363301A0 (en) * | 2001-03-08 | 2001-04-05 | Novogen Research Pty Ltd | Dimeric isoflavones |
| US8178123B2 (en) | 2001-08-29 | 2012-05-15 | Femina Pharma Incorporated | Method for augmentation of intraepithelial and systemic exposure of therapeutic agents having substrate activity for cytochrome P450 enzymes and membrane efflux systems following vaginal and oral cavity administration |
| AUPR846401A0 (en) * | 2001-10-25 | 2001-11-15 | Novogen Research Pty Ltd | 6-Hydroxy isoflavones, derivatives and medicaments involving same |
| MXPA04009896A (es) | 2002-04-09 | 2005-06-17 | Novogen Res Pty Ltd | Metodos terapeuticos y composiciones que implican estructuras de tipo isoflav-3-eno e isoflavano. |
| US9173866B2 (en) | 2002-07-24 | 2015-11-03 | Children's Hospital Medical Center | Compositions and products containing R-equol, and methods for their making |
| AU2002951833A0 (en) * | 2002-10-02 | 2002-10-24 | Novogen Research Pty Ltd | Compositions and therapeutic methods invloving platinum complexes |
| AU2002952453A0 (en) * | 2002-11-01 | 2002-11-21 | Novogen Research Pty Ltd | Aminated isoflavonoid derivatives and uses thereof |
| AU2004273910A1 (en) * | 2003-09-18 | 2005-03-31 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
| US20050154452A1 (en) | 2003-12-23 | 2005-07-14 | Medtronic Vascular, Inc. | Medical devices to treat or inhibit restenosis |
| US7434690B2 (en) | 2004-04-30 | 2008-10-14 | Cutispharma, Inc. | Container and method for the preparation, storage and dispensing of compounded suppositories |
| US8080675B2 (en) * | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| EP1809618B1 (en) | 2004-09-21 | 2013-07-17 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
| ATE532777T1 (de) * | 2004-09-21 | 2011-11-15 | Marshall Edwards Inc | Substituierte chromanderivate, medikamente und anwendungen in der therapie |
| DE102005009515A1 (de) | 2005-02-25 | 2006-09-07 | Exner, Heinrich, Dr. | Verfahren zur Herstellung einer Zubereitung einer DMSO-haltigen festen Silikonölemulsion zur Bindung von reaktiven Sauerstoffverbindungen im Körper von Menschen und Tieren |
| US20090131513A1 (en) | 2005-03-24 | 2009-05-21 | Novogen Research Pty Ltd. | Anti-inflammatory modalities |
| JP2009508869A (ja) | 2005-09-15 | 2009-03-05 | ユーエムディー, インコーポレイテッド | シトクロムp450についての基質活性を持つ上皮内及び全体的な曝露の増大のための方法、及び膜流出系それに次ぐ鞘及び口腔の管理 |
| US20070196381A1 (en) | 2006-02-17 | 2007-08-23 | Natures Benefit, Inc. | Herbal compositions, methods of stimulating immunomodulation and enhancement of immunomodulating agents using the herbal compositions |
| WO2008052256A1 (en) | 2006-10-30 | 2008-05-08 | Novogen Research Pty Ltd | Prevention and reversal of chemotherapy-induced peripheral neuropathy |
| EP2160385A4 (en) * | 2007-06-29 | 2010-10-27 | Novogen Res Pty Ltd | 2-SUBSTITUTED ISOFLAVONOID COMPOUNDS AND MEDICAMENTS THEREOF AND APPLICATIONS THEREOF |
| US8729134B2 (en) | 2008-11-14 | 2014-05-20 | Heartlink Limited | Aryl di-substituted propenone compounds |
| KR20110004525A (ko) | 2009-07-08 | 2011-01-14 | 동의대학교 산학협력단 | 제니스테인과 trail을 포함하는 간암 치료용 조성물 |
| ES2365960B1 (es) | 2010-03-31 | 2012-06-04 | Palobiofarma, S.L | Nuevos antagonistas de los receptores de adenosina. |
| EP2766500A4 (en) * | 2011-10-14 | 2015-10-14 | Univ Ohio State | METHOD AND MATERIALS IN CONNECTION WITH EGG CANCER |
| ES2734568T3 (es) * | 2013-03-13 | 2019-12-10 | Oncoceutics Inc | 7-Bencil-10-(2-metilbencil)-2,6,7,8,9,10-hexahidroimidazo[1,2-a]pirido[4,3-d]pirimidin-5(3H)-ona para su uso en el tratamiento de cáncer |
| US20150126597A1 (en) * | 2013-11-07 | 2015-05-07 | Humanetics Corporation | Genistein cancer treatment regimen maximizing cancer radiation therapy benefits |
| SG11201604490SA (en) * | 2014-02-07 | 2016-07-28 | Novogen ltd | Functionalised benzopyran compounds and use thereof |
| SG10202111808WA (en) | 2015-08-11 | 2021-11-29 | Novartis Ag | 5-bromo-2,6-di-(1h-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer |
| CN108884159A (zh) * | 2015-11-07 | 2018-11-23 | 茂体外尔公司 | 用于癌症治疗的包含肿瘤抑制基因治疗和免疫检查点阻断的组合物 |
| AU2017247006B2 (en) * | 2016-04-06 | 2022-05-12 | Noxopharm Limited | Radiotherapy improvements |
| CA3058503A1 (en) | 2016-04-06 | 2017-10-12 | Noxopharm Limited | Isoflavonoid composition with improved pharmacokinetics |
| AU2016401508B2 (en) * | 2016-04-06 | 2020-03-26 | Noxopharm Limited | Improvements in cancer treatment |
| EP4035667A1 (en) * | 2016-04-22 | 2022-08-03 | Noxopharm Limited | Chemotherapy improvements with idronoxil |
| JP7329860B2 (ja) | 2018-06-15 | 2023-08-21 | ボード オブ レジェンツ,ザ ユニバーシティ オブ テキサス システム | S-エクオールを用いた乳癌の治療及び予防方法 |
| AU2019285641A1 (en) | 2018-06-15 | 2021-04-08 | The Board Of Regents Of The University Of Texas System | Methods of treating and preventing melanoma with s-equol |
| WO2020051644A1 (en) | 2018-09-13 | 2020-03-19 | Norbio No. 2 Pty Ltd | Treatment of peripheral nervous tissue inflammation |
-
2017
- 2017-04-06 AU AU2017247006A patent/AU2017247006B2/en not_active Ceased
- 2017-04-06 JP JP2019503597A patent/JP2019513826A/ja active Pending
- 2017-04-06 EP EP17778480.8A patent/EP3439642A4/en not_active Withdrawn
- 2017-04-06 US US16/091,706 patent/US11229703B2/en active Active
- 2017-04-06 CA CA3058492A patent/CA3058492A1/en not_active Abandoned
- 2017-04-06 WO PCT/AU2017/050299 patent/WO2017173496A1/en not_active Ceased
-
2021
- 2021-12-14 US US17/644,211 patent/US20220105182A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007525485A (ja) * | 2003-11-19 | 2007-09-06 | ノボゲン リサーチ ピーティーワイ リミテッド | 複合的な放射線治療及び化学治療の組成物及び方法 |
| JP2012500809A (ja) * | 2008-08-29 | 2012-01-12 | ノボゲン リサーチ ピーティーワイ リミテッド | 免疫調節活性 |
Non-Patent Citations (3)
| Title |
|---|
| INT. J. MOL. SCI., vol. 15, JPN6021011589, 2014, pages 927 - 943, ISSN: 0004710777 * |
| JPN. J. MED. PHYS., vol. 34, no. 2, JPN6021011592, 2014, pages 70 - 78, ISSN: 0004710778 * |
| がん分子標的治療, vol. 13, no. 4, JPN6021011586, 2015, pages 24 - 28, ISSN: 0004710776 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190262451A1 (en) | 2019-08-29 |
| US20220105182A1 (en) | 2022-04-07 |
| CA3058492A1 (en) | 2017-10-12 |
| AU2017247006A1 (en) | 2018-11-01 |
| WO2017173496A1 (en) | 2017-10-12 |
| EP3439642A1 (en) | 2019-02-13 |
| AU2017247006B2 (en) | 2022-05-12 |
| US11229703B2 (en) | 2022-01-25 |
| EP3439642A4 (en) | 2019-11-13 |
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