JP2019513412A5 - - Google Patents

Download PDF

Info

Publication number
JP2019513412A5
JP2019513412A5 JP2018568171A JP2018568171A JP2019513412A5 JP 2019513412 A5 JP2019513412 A5 JP 2019513412A5 JP 2018568171 A JP2018568171 A JP 2018568171A JP 2018568171 A JP2018568171 A JP 2018568171A JP 2019513412 A5 JP2019513412 A5 JP 2019513412A5
Authority
JP
Japan
Prior art keywords
cells
nanoparticles
paramagnetic
expanded
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018568171A
Other languages
English (en)
Japanese (ja)
Other versions
JP7016098B2 (ja
JP2019513412A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/022663 external-priority patent/WO2017161092A1/en
Publication of JP2019513412A publication Critical patent/JP2019513412A/ja
Publication of JP2019513412A5 publication Critical patent/JP2019513412A5/ja
Application granted granted Critical
Publication of JP7016098B2 publication Critical patent/JP7016098B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018568171A 2016-03-16 2017-03-16 抗原特異的t細胞の生成 Active JP7016098B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662309234P 2016-03-16 2016-03-16
US62/309,234 2016-03-16
PCT/US2017/022663 WO2017161092A1 (en) 2016-03-16 2017-03-16 Production of antigen-specific t-cells

Publications (3)

Publication Number Publication Date
JP2019513412A JP2019513412A (ja) 2019-05-30
JP2019513412A5 true JP2019513412A5 (https=) 2020-04-23
JP7016098B2 JP7016098B2 (ja) 2022-02-21

Family

ID=59850933

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018568171A Active JP7016098B2 (ja) 2016-03-16 2017-03-16 抗原特異的t細胞の生成

Country Status (11)

Country Link
US (2) US20200291381A1 (https=)
EP (1) EP3445399A4 (https=)
JP (1) JP7016098B2 (https=)
KR (1) KR102470979B1 (https=)
CN (1) CN109475620A (https=)
AU (1) AU2017233035B2 (https=)
CA (1) CA3017615A1 (https=)
IL (1) IL261710A (https=)
RU (2) RU2021107053A (https=)
SG (2) SG10202008210XA (https=)
WO (1) WO2017161092A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3475706B1 (en) * 2016-06-27 2021-08-11 Juno Therapeutics, Inc. Mhc-e restricted epitopes, binding molecules and related methods and uses
BR112020005552A2 (pt) * 2017-09-20 2020-10-27 Neximmune, Inc. composições de células compreendendo células t específicas de antígeno para terapia adotiva
EP3691662A4 (en) * 2017-10-06 2021-05-12 The University of Chicago SCREENING OF T LYMPHOCYTE FOR CANCER SPECIFIC ANTIGENS
JP7580754B2 (ja) * 2018-06-20 2024-11-12 ダンマークス テクニスク ユニバーシテット 免疫細胞操作用の安定化されたmhc分子を有するスカフォールド
WO2020061256A1 (en) * 2018-09-19 2020-03-26 FUJIFILM Cellular Dynamics, Inc. Protein l for activation and expansion of chimeric antigen receptor-modified immune cells
CN109136276A (zh) * 2018-09-30 2019-01-04 北京鼎成肽源生物技术有限公司 一种rfft2细胞的构建方法
SG11202104611YA (en) 2018-11-08 2021-06-29 Neximmune Inc T cell compositions with improved phenotypic properties
US12600755B2 (en) 2020-02-27 2026-04-14 The George Washington University, A Congressionally Chartered Not-For-Profit Corporation Cobra 1/NELF-B as a booster for efficacy of CD8+ T cell-based therapy
WO2021262846A1 (en) * 2020-06-26 2021-12-30 The Johns Hopkins University Adaptive nanoparticle platforms for high throughput expansion and detection of antigen-specific t cells
US20240066062A1 (en) * 2020-12-11 2024-02-29 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2022194742A1 (en) * 2021-03-17 2022-09-22 Miltenyi Biotec B.V. & Co. KG Artificial target for the antigen-specific activation and expansion of car t cells
US20250032617A1 (en) * 2021-10-08 2025-01-30 Baylor College Of Medicine Transgenic t cell receptors targeting neoantigens for diagnosis, prevention, and/or treatment of hematological cancers
WO2023144275A1 (en) * 2022-01-28 2023-08-03 Katholieke Universiteit Leuven Actuation of organoids by magnetic nanoparticles
DE102022132082B4 (de) * 2022-12-02 2024-08-08 Horia Hulubei National Institute for R & D in Physics and Nuclear Engineering (IFIN-HH) Verfahren zur Herstellung von genetisch transfizierten und mit Nanopartikeln und/oder einem zytotoxischen Stoff beladenen immunokompetenten Zellen sowie immunokompetente Zellen und medizinische Zusammensetzung.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2311920C2 (ru) * 2000-09-20 2007-12-10 Корикса Корпорейшн Композиции и способы для лечения и диагностики рака легких
TW200502391A (en) * 2003-05-08 2005-01-16 Xcyte Therapies Inc Generation and isolation of antigen-specific t cells
AT503861B1 (de) * 2006-07-05 2008-06-15 F Star Biotech Forsch & Entw Verfahren zur manipulation von t-zell-rezeptoren
US20120128656A1 (en) * 2008-05-02 2012-05-24 Immunovative Therapies, Ltd. Vaccine compositions and methods
CN102168066A (zh) * 2011-01-31 2011-08-31 浙江大学 体外诱导乙型肝炎病毒特异性细胞毒性t淋巴细胞的方法
JP6482461B2 (ja) * 2012-07-13 2019-03-13 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 投与に関する形質導入t細胞の適合性の評価方法
KR102164405B1 (ko) * 2013-03-14 2020-10-12 더 존스 홉킨스 유니버시티 나노스케일 인공 항원 제시 세포
US11807675B2 (en) * 2013-10-03 2023-11-07 The University Of Maryland, Baltimore Nanoparticle based artificial antigen presenting cell mediated activation of NKT cells
US10066265B2 (en) * 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
KR20160016725A (ko) * 2014-08-05 2016-02-15 주식회사 유영제약 암 세포에 과발현되는 IL13Rα2에 특이적으로 결합하는 키메라 항원 수용체로 변형된 T 세포

Similar Documents

Publication Publication Date Title
JP2019513412A5 (https=)
Huff et al. The evolving role of CD8+ CD28− immunosenescent T cells in cancer immunology
Parent et al. Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
Pang et al. Current progress of CAR-NK therapy in cancer treatment
Lässer et al. Isolation and characterization of RNA-containing exosomes
JP6902018B2 (ja) キメラ抗原受容体及び他の受容体の発現に対するt細胞
JP2016509839A5 (https=)
JP2016509840A5 (https=)
Suck et al. Natural killer cells for therapy of leukemia
Hefazi et al. Regulatory T cell therapy of graft-versus-host disease: advances and challenges
JP2016539929A5 (https=)
JP2013177430A5 (https=)
WO2018175408A8 (en) METHODS AND COMPOSITIONS FOR MODULATION OF IMMUNE CELLS
Stockinger et al. CD4 T-cell memory
Després et al. CD34+ cell enrichment for autologous peripheral blood stem cell transplantation by use of the CliniMACs device
van Bruggen et al. Overcoming the hurdles of autologous T-cell-based therapies in B-cell non-hodgkin lymphoma
Lee et al. Phenotypic and functional changes of peripheral Ly6C+ T regulatory cells driven by conventional effector T cells
Avecilla et al. How do I perform hematopoietic progenitor cell selection?
Fang et al. Adoptive cell therapy for T-cell malignancies
Gossel et al. Retargeting of NK-92 cells against high-risk rhabdomyosarcomas by means of an ERBB2 (HER2/Neu)-specific chimeric antigen receptor
Edri et al. Nicotinamide-expanded allogeneic natural killer cells with CD38 deletion, expressing an enhanced CD38 chimeric antigen receptor, target multiple myeloma cells
Plantinga et al. Cord-blood-stem-cell-derived conventional dendritic cells specifically originate from CD115-expressing precursors
Son et al. Enhanced maturation and function of dendritic cells using hydrogel coated plate and antigen electroporation
JP2020535832A5 (https=)
Kim et al. X-ray as irradiation alternative for K562 feeder cell inactivation in human natural killer cell expansion