JP2019513126A5 - - Google Patents
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- Publication number
- JP2019513126A5 JP2019513126A5 JP2018545900A JP2018545900A JP2019513126A5 JP 2019513126 A5 JP2019513126 A5 JP 2019513126A5 JP 2018545900 A JP2018545900 A JP 2018545900A JP 2018545900 A JP2018545900 A JP 2018545900A JP 2019513126 A5 JP2019513126 A5 JP 2019513126A5
- Authority
- JP
- Japan
- Prior art keywords
- ethoxy
- amino
- xaa
- acetyl
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 *C(c(cc1)ccc1OCCCCCCCC=O)=O Chemical compound *C(c(cc1)ccc1OCCCCCCCC=O)=O 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16158388.5 | 2016-03-03 | ||
| EP16158388 | 2016-03-03 | ||
| PCT/EP2017/054895 WO2017149070A1 (en) | 2016-03-03 | 2017-03-02 | Glp-1 derivatives and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019513126A JP2019513126A (ja) | 2019-05-23 |
| JP2019513126A5 true JP2019513126A5 (https=) | 2020-04-09 |
| JP7053480B2 JP7053480B2 (ja) | 2022-04-12 |
Family
ID=55451126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545900A Active JP7053480B2 (ja) | 2016-03-03 | 2017-03-02 | Ｇｌｐ－１誘導体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10946074B2 (https=) |
| EP (1) | EP3423481B1 (https=) |
| JP (1) | JP7053480B2 (https=) |
| CN (1) | CN108699126B (https=) |
| ES (1) | ES2835033T3 (https=) |
| WO (1) | WO2017149070A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20240485T1 (hr) | 2017-08-24 | 2024-07-05 | Novo Nordisk A/S | Pripravci glp-1 i njihova upotreba |
| RS63523B1 (sr) | 2018-04-05 | 2022-09-30 | Sun Pharmaceutical Ind Ltd | Novi glp-1 analozi |
| CN110386974B (zh) * | 2018-04-19 | 2022-12-09 | 杭州先为达生物科技有限公司 | Glp-1衍生物及其治疗用途 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| WO2020104833A1 (en) | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN109730270B (zh) * | 2019-02-12 | 2022-06-28 | 西安培华学院 | 一种降糖酵母发酵南瓜粉及制备方法和应用 |
| PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
| WO2021239082A1 (zh) * | 2020-05-29 | 2021-12-02 | 北京拓界生物医药科技有限公司 | Glp-1和gip受体双重激动剂化合物及其应用 |
| CN114729060B (zh) | 2020-09-30 | 2022-11-25 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
| WO2022159395A1 (en) | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| MX2024003236A (es) | 2021-09-15 | 2024-06-19 | Viking Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos. |
| CN116650424A (zh) * | 2022-01-06 | 2023-08-29 | 鸿绪生物医药科技（北京）有限公司 | 新型多肽制剂及其治疗用途 |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| CN114984191B (zh) * | 2022-07-04 | 2022-10-25 | 北京惠之衡生物科技有限公司 | 一种多肽类药物口服递送组合物 |
| WO2026008836A1 (en) | 2024-07-05 | 2026-01-08 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
| WO2026019692A2 (en) * | 2024-07-15 | 2026-01-22 | Flagship Pioneering Innovations Vii, Llc | Immunomodulatory fusion proteins and related methods |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| CA2363123C (en) | 1999-02-22 | 2011-09-06 | Kenneth Iain Cumming | Solid oral dosage form containing an enhancer |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| US20110144010A1 (en) | 2007-06-01 | 2011-06-16 | Novo Nordisk A/S | Spontaneously Dispersible Preconcentrates Including a Peptide Drug in a Solid or Semisolid Carrier |
| EP2190872B1 (en) | 2007-09-05 | 2018-03-14 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US20100317057A1 (en) | 2007-12-28 | 2010-12-16 | Novo Nordisk A/S | Semi-recombinant preparation of glp-1 analogues |
| CN101255191A (zh) | 2008-03-12 | 2008-09-03 | 中国药科大学 | 微波促进固相合成胰高血糖素样肽-1(glp-1)类似物及其应用 |
| EP2398822B1 (en) | 2009-02-19 | 2013-01-02 | Novo Nordisk A/S | Modification of factor viii |
| EP2512518A1 (en) | 2009-12-16 | 2012-10-24 | Novo Nordisk A/S | Glp-1 receptor agonist compounds with a modified n-terminus |
| MX377589B (es) | 2010-12-16 | 2025-03-10 | Novo Nordisk As | Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico. |
| RU2602601C2 (ru) * | 2011-04-12 | 2016-11-20 | Ново Нордиск А/С | Дважды ацилированные производные glp-1 |
| CN102180963B (zh) | 2011-04-22 | 2014-06-25 | 中国药科大学 | 胰高血糖素样肽-1(glp-1)类似物及其应用 |
| JP6046161B2 (ja) | 2011-12-29 | 2016-12-14 | ノヴォ ノルディスク アー／エス | 非タンパク質新生アミノ酸を含むジペプチド |
| CN104203266B (zh) | 2012-03-22 | 2017-12-26 | 诺和诺德股份有限公司 | Glp‑1肽组合物及其制备 |
| CN103087178A (zh) | 2012-11-30 | 2013-05-08 | 中国药科大学 | 长效化胰高血糖素样肽-1(glp-1)类似物及其应用 |
| KR20160021183A (ko) * | 2013-06-20 | 2016-02-24 | 노보 노르디스크 에이/에스 | Glp-1 유도체 및 그것의 용도 |
| WO2015000942A1 (en) | 2013-07-04 | 2015-01-08 | Novo Nordisk A/S | Derivatives of glp-1 like peptides, and uses thereof |
| EP3107937A4 (en) | 2014-02-21 | 2017-11-15 | MedImmune, LLC | Anti-pcsk9~glp-1 fusions and methods for use |
| US10689429B2 (en) | 2014-04-07 | 2020-06-23 | Novo Nordisk A/S | Double-acylated GLP-1 compounds |
| JP6730278B2 (ja) | 2014-11-27 | 2020-07-29 | ノヴォ ノルディスク アー／エス | Ｇｌｐ−１誘導体及びその使用 |
| WO2016097108A1 (en) | 2014-12-17 | 2016-06-23 | Novo Nordisk A/S | Glp-1 derivatives and uses thereof |
-
2017
- 2017-03-02 WO PCT/EP2017/054895 patent/WO2017149070A1/en not_active Ceased
- 2017-03-02 JP JP2018545900A patent/JP7053480B2/ja active Active
- 2017-03-02 EP EP17708491.0A patent/EP3423481B1/en active Active
- 2017-03-02 US US16/077,759 patent/US10946074B2/en active Active
- 2017-03-02 ES ES17708491T patent/ES2835033T3/es active Active
- 2017-03-02 CN CN201780014939.5A patent/CN108699126B/zh active Active
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