ES2835033T3 - Derivados de GLP-1 y sus usos - Google Patents

Derivados de GLP-1 y sus usos Download PDF

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Publication number
ES2835033T3
ES2835033T3 ES17708491T ES17708491T ES2835033T3 ES 2835033 T3 ES2835033 T3 ES 2835033T3 ES 17708491 T ES17708491 T ES 17708491T ES 17708491 T ES17708491 T ES 17708491T ES 2835033 T3 ES2835033 T3 ES 2835033T3
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Spain
Prior art keywords
ethoxy
amino
glp
acetyl
chemical compound
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ES17708491T
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English (en)
Spanish (es)
Inventor
Jacob Kofoed
János Kodra
Lars Linderoth
Patrick Garibay
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Novo Nordisk AS
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Novo Nordisk AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
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    • C—CHEMISTRY; METALLURGY
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Addiction (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
ES17708491T 2016-03-03 2017-03-02 Derivados de GLP-1 y sus usos Active ES2835033T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16158388 2016-03-03
PCT/EP2017/054895 WO2017149070A1 (en) 2016-03-03 2017-03-02 Glp-1 derivatives and uses thereof

Publications (1)

Publication Number Publication Date
ES2835033T3 true ES2835033T3 (es) 2021-06-21

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ES17708491T Active ES2835033T3 (es) 2016-03-03 2017-03-02 Derivados de GLP-1 y sus usos

Country Status (6)

Country Link
US (1) US10946074B2 (https=)
EP (1) EP3423481B1 (https=)
JP (1) JP7053480B2 (https=)
CN (1) CN108699126B (https=)
ES (1) ES2835033T3 (https=)
WO (1) WO2017149070A1 (https=)

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HRP20240485T1 (hr) 2017-08-24 2024-07-05 Novo Nordisk A/S Pripravci glp-1 i njihova upotreba
RS63523B1 (sr) 2018-04-05 2022-09-30 Sun Pharmaceutical Ind Ltd Novi glp-1 analozi
CN110386974B (zh) * 2018-04-19 2022-12-09 杭州先为达生物科技有限公司 Glp-1衍生物及其治疗用途
TWI829687B (zh) 2018-05-07 2024-01-21 丹麥商諾佛 儂迪克股份有限公司 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
WO2020104833A1 (en) 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN109730270B (zh) * 2019-02-12 2022-06-28 西安培华学院 一种降糖酵母发酵南瓜粉及制备方法和应用
PE20230819A1 (es) 2020-02-18 2023-05-19 Novo Nordisk As Composiciones y usos de glp-1
WO2021239082A1 (zh) * 2020-05-29 2021-12-02 北京拓界生物医药科技有限公司 Glp-1和gip受体双重激动剂化合物及其应用
CN114729060B (zh) 2020-09-30 2022-11-25 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
WO2022159395A1 (en) 2021-01-20 2022-07-28 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
MX2024003236A (es) 2021-09-15 2024-06-19 Viking Therapeutics Inc Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos.
CN116650424A (zh) * 2022-01-06 2023-08-29 鸿绪生物医药科技（北京）有限公司 新型多肽制剂及其治疗用途
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF
CN114984191B (zh) * 2022-07-04 2022-10-25 北京惠之衡生物科技有限公司 一种多肽类药物口服递送组合物
WO2026008836A1 (en) 2024-07-05 2026-01-08 Novo Nordisk A/S Glp-1 derivatives and uses thereof
WO2026019692A2 (en) * 2024-07-15 2026-01-22 Flagship Pioneering Innovations Vii, Llc Immunomodulatory fusion proteins and related methods

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